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Ethyl 2,3,4,5-tetrafluorobenzoate, a colorless liquid with a fruity odor, is a chemical compound characterized by the molecular formula C9H7F4O2. It is widely recognized for its role as an intermediate in the synthesis of pharmaceuticals and agrochemicals, and is also valued for its strong repellent properties against mosquitoes and other insects. Ethyl 2,3,4,5-tetrafluorobenzoate is soluble in most organic solvents and remains stable under normal storage conditions, while being generally considered non-toxic, although proper safety precautions are still advised during handling.

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  • 122894-73-9 Structure
  • Basic information

    1. Product Name: Ethyl 2,3,4,5-tetrafluorobenzoate
    2. Synonyms: 2,3,4,5-TETRAFLUORO-BENZOIC ACID ETHYL ESTER;ETHYL 2,3,4,5-TETRAFLUOROBENZOATE;RARECHEM AL BI 0650;5-Tetrafluoro-benzoic acid ethyl ester;ethy-2,3,4,5-tetrafluorobenzoate;Ethyl 2H-tetrafluorobenzoate;Benzoic acid,2,3,4,5-tetrafluoro-, ethyl ester
    3. CAS NO:122894-73-9
    4. Molecular Formula: C9H6F4O2
    5. Molecular Weight: 222.1363528
    6. EINECS: N/A
    7. Product Categories: Aromatic Esters;Benzoic acid
    8. Mol File: 122894-73-9.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 238-239°C
    3. Flash Point: 95°C
    4. Appearance: white crystal powder
    5. Density: 1.382
    6. Refractive Index: 1.4440
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: Ethyl 2,3,4,5-tetrafluorobenzoate(CAS DataBase Reference)
    10. NIST Chemistry Reference: Ethyl 2,3,4,5-tetrafluorobenzoate(122894-73-9)
    11. EPA Substance Registry System: Ethyl 2,3,4,5-tetrafluorobenzoate(122894-73-9)
  • Safety Data

    1. Hazard Codes: Xi
    2. Statements: N/A
    3. Safety Statements: 24/25
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 122894-73-9(Hazardous Substances Data)

122894-73-9 Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
Ethyl 2,3,4,5-tetrafluorobenzoate is utilized as a key intermediate in the synthesis of various pharmaceuticals and agrochemicals, contributing to the development of new drugs and pesticides. Its unique chemical structure allows for the creation of compounds with specific therapeutic or pesticidal properties.
Used in Insect Repellent Applications:
Due to its strong repellent properties, Ethyl 2,3,4,5-tetrafluorobenzoate is employed as an active ingredient in insect repellent products. It is particularly effective against mosquitoes and other insects, providing protection against bites and the diseases they may transmit.
Used in Chemical Research:
Ethyl 2,3,4,5-tetrafluorobenzoate is also used in chemical research for the study of its properties and potential applications. Its unique structure and reactivity make it a valuable subject for investigations into new chemical reactions and processes.

Check Digit Verification of cas no

The CAS Registry Mumber 122894-73-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,2,8,9 and 4 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 122894-73:
(8*1)+(7*2)+(6*2)+(5*8)+(4*9)+(3*4)+(2*7)+(1*3)=139
139 % 10 = 9
So 122894-73-9 is a valid CAS Registry Number.

122894-73-9 Well-known Company Product Price

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  • Alfa Aesar

  • (B21920)  Ethyl 2,3,4,5-tetrafluorobenzoate, 98%   

  • 122894-73-9

  • 2g

  • 698.0CNY

  • Detail
  • Alfa Aesar

  • (B21920)  Ethyl 2,3,4,5-tetrafluorobenzoate, 98%   

  • 122894-73-9

  • 10g

  • 1556.0CNY

  • Detail

122894-73-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 10, 2017

Revision Date: Aug 10, 2017

1.Identification

1.1 GHS Product identifier

Product name Ethyl 2,3,4,5-Tetrafluorobenzoate

1.2 Other means of identification

Product number -
Other names Ethyl 2,3,4,5-tetrafluorobenzoate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:122894-73-9 SDS

122894-73-9Downstream Products

122894-73-9Relevant articles and documents

Regioselective ortho-hydrodefluorination of pentafluorobenzoic acid by low-valent nickel complexes

Adonin,Starichenko

, p. 65 - 67 (2007/10/03)

2,3,4,5-Tetrafluorobenzoic and 3,4,5-trifluorobenzoic acids were prepared in high yields by reaction of C6F5COOH with zinc in the presence of NiCl2-2′-bipyridine (or 1,10-phenanthroline) complexes.

Pyridonecarboxylic acids as antibacterial agents. VIII. Synthesis and structure-activity relationship of 7-(1-aminocyclopropyl)-4-oxo-1,8-naphthyridine-3-carboxylic acids and 7-(1-aminocyclopropyl)-4-oxoquinoline-3-carboxylic acids

Todo,Nitta,Miyajima,Fukuoka,Yamashiro,Nishida,Saikawa,Narita

, p. 2063 - 2070 (2007/10/02)

4-Oxo-1,8-naphthyridine- and 4-oxoquinoline-3-carboxylic acids (2a, b and 3a-l) possessing a 1-aminocyclopropyl group at the 7-position have been synthesized and evaluated for in vitro antibacterial activities. The three quinolones (3d, h, i) exhibited potent antibacterial activities against both gram-positive and gram-negative bacteria, which are comparable to those of ciprofloxacin (CPFX) and ofloxacin (OFLX). Among the three compounds, the best pharmacological and pharmacokinetic profile was obtained with 3i, an OFLX analogue, which was considerably less toxic than three reference quinolones (1, CPFX, and OFLX).

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