124-05-0

Basic information

• Product Name: ETHYLENEBIS(CHLOROFORMATE) PURISS 98
• Synonyms: ETHYLENEBIS(CHLOROFORMATE) PURISS 98;1,2-bis((chlorocarbonyl)oxy)ethane;carbonochlorideacid,1,2-ethanediylester;carbonochloridicacid,1,2-ethanediylester;chloro-formicaciethyleneester;ethylenechloroformate;ethyleneglycoldi(chloroformate);ETHYLENEBIS(CHLOROFORMATE), PURISS, 98%
• CAS NO: 124-05-0
• Molecular Formula: C₄H₄Cl₂O₄
• Molecular Weight: 186.98
• EINECS: 204-674-9
• Product Categories: Acid Halides;Carbonyl Compounds;Organic Building Blocks
• Mol File: 124-05-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 53-55 °C0.3 mm Hg(lit.)
• Flash Point: >230 °F
• Appearance: /
• Density: 1.436 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.146mmHg at 25°C
• Refractive Index: n20/D 1.436(lit.)
• Storage Temp.: 2-8°C
• CAS DataBase Reference: ETHYLENEBIS(CHLOROFORMATE) PURISS 98(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYLENEBIS(CHLOROFORMATE) PURISS 98(124-05-0)
• EPA Substance Registry System: ETHYLENEBIS(CHLOROFORMATE) PURISS 98(124-05-0)

Safety Data

• Hazard Codes: C
• Statements: 22-34
• Safety Statements: 26-36/37/39-45
• RIDADR: UN 3265 8/PG 3
• WGK Germany: 3
• RTECS: LQ6000000
• Hazardous Substances Data: 124-05-0(Hazardous Substances Data)

Usage

Safety Profile

Moderately toxic by ingestion and skin contact. Mildly toxic by inhalation. When heated to decomposition it emits toxic fumes of Cl

InChI:InChI=1/C4H4Cl2O4/c5-3(7)9-1-2-10-4(6)8/h1-2H2

Upstream product

• 75-44-5 phosgene 
• 107-21-1 ethylene glycol 
• 60-80-0 antipyrine 

Downstream Products

• 109697-20-3 C₁₈H₁₄O₈ 
• 56456-33-8 C₂₀H₁₆I₆N₄O₈ 
• 6298-82-4 Bis(morpholinoameisensaeure)-ethylester 
• 5347-26-2 1,2-bis-(3-chloro-phenylcarbamoyloxy)-ethane 
• 4074-91-3 2,5-dioxa-adipic acid diallyl ester 
• 42775-58-6 ethylene glycol bis(N-cyclohexylcarbamate) 
• 75-34-3 1,1-dichloroethane 
• 5130-24-5 Vinyl chloroformate 
• 50893-53-3 carbonochloridic acid 1-chloro-ethyl ester 
• 627-11-2 2-Chloroethyl chloroformate 
• 19150-42-6 ethane-1,2-diyl dicarbamate 
• 103159-16-6 1,2-bis-[4-(2-diethylamino-ethoxy)-phenylcarbamoyloxy]-ethane 
• 35466-87-6 diethyl 2,5-dioahexane dicarboxylate 
• 88754-66-9 2,5-dioxa-adipic acid dimethyl ester 

Relevant articles and documents

Method for the preparation of aliphatic chloroformates

A method for preparing an aliphatic chloroformate comprising, introducing a mixture of at least one aliphatic hydroxyl compound, phosgene, at least one solvent, and optionally at least one organic base into a flow reactor to obtain a unidirectional flowing reaction mixture. The at least one aliphatic hydroxyl compound comprises at least one aliphatic hydroxyl group. The unidirectional flowing reaction mixture is maintained at a temperature between about 0° C. and about 60° C. to produce a single product stream comprising an aliphatic chloroformate.

1-Aziridine carboxylic acid derivatives with immunostimulant activity

2-Substituted-1-aziridine-carboxylic acid esters exhibiting immuno-stimulant activity and of the formula STR1 wherein X is a carbamoyl or alkoxycarbonyl radical, and R1 is an aliphatic hydrocarbon radical optionally substituted by halogen, alkoxy, amino, carbamoyloxy, cycloalkyl, hydroxyl, an imido or heterocyclic radical, cycloalkyl; or aryl, aralkyl, aryloxyalkyl or arylthioalkyl wherein the aryl moiety is optionally substituted by halogen, alkyl, alkoxy, hydroxyl, amino, nitro, cyano, acyl, carbalkoxy, thioalkyl, alkylsulphonyl, phenyl or trifluoromethyl. Counterparts where X is --CN and R1 is as above, except for ethyl, are also new.