Welcome to LookChem.com Sign In|Join Free

CAS

  • or

1244-58-2

Cannabidiolic acid (CBDA) is a naturally occurring phytocannabinoid found in fiber-type cannabis plants. It is produced through the enzymatic conversion of cannabigerolic acid by cannabidiolic acid synthase. CBDA is a dihydroxybenzoic acid derivative with a unique structure, featuring a 3-p-mentha-1,8-dien-3-yl (limonene) group substitution at the hydrogen position 3. cannabidiolic acid is primarily used for research and forensic applications, and it holds potential therapeutic value in the medical field.

1244-58-2 Suppliers

This product is a nationally controlled contraband or patented product, and the Lookchem platform doesn't provide relevant sales information.
  • 1244-58-2 Structure

  • Basic information

    1. Product Name: cannabidiolic acid
    2. Synonyms: cannabidiolic acid;2,4-Dihydroxy-3-[(1R,6R)-3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl]-6-pentylbenzoic acid;2,4-Dihydroxy-3-[(1R,6R)-3-methyl-6-isopropenyl-2-cyclohexenyl]-6-pentylbenzoic acid;2,4-dihydroxy-3-[(1R,6R)-3-methyl-6-prop-1-en-2-yl-cyclohex-2-en-1-yl]-6-pentyl-benzoic acid;2,4-dihydroxy-3-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-6-pentylbenzoic acid;6-amyl-2,4-dihydroxy-3-[(1R,6R)-6-isopropenyl-3-methyl-cyclohex-2-en-1-yl]benzoic acid;Cannabidiolic Acid (CRM)
    3. CAS NO:1244-58-2
    4. Molecular Formula: C22H30O4
    5. Molecular Weight: 358.47
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1244-58-2.mol

  • Chemical Properties

    1. Melting Point: 45-48 °C
    2. Boiling Point: 530.8°Cat760mmHg
    3. Flash Point: 2℃
    4. Appearance: /
    5. Density: 1.123g/cm3
    6. Vapor Pressure: 4.27E-12mmHg at 25°C
    7. Refractive Index: 1.564
    8. Storage Temp.: −20°C
    9. Solubility: N/A
    10. PKA: 3.41±0.43(Predicted)
    11. CAS DataBase Reference: cannabidiolic acid(CAS DataBase Reference)
    12. NIST Chemistry Reference: cannabidiolic acid(1244-58-2)
    13. EPA Substance Registry System: cannabidiolic acid(1244-58-2)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. RIDADR: UN 1648 3 / PGII
    5. WGK Germany: 3
    6. RTECS:
    7. HazardClass: N/A
    8. PackingGroup: N/A
    9. Hazardous Substances Data: 1244-58-2(Hazardous Substances Data)

1244-58-2 Usage

Uses

Used in Pharmaceutical Industry:
Cannabidiolic acid is used as a therapeutic agent for its potential value in the treatment of aggressive breast cancers. It acts as an inhibitor of MDA-MB-231 breast cancer cell migration, which can help in the abrogation of cancer cell migration and the management of aggressive breast cancers.
Used in Research and Forensic Applications:
Cannabidiolic acid serves as a certified reference material for research purposes, aiding in the study of its properties, mechanisms of action, and potential applications in the medical and pharmaceutical fields. It is also utilized in forensic applications for the identification and analysis of cannabinoids in various samples.

Check Digit Verification of cas no

The CAS Registry Mumber 1244-58-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,2,4 and 4 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1244-58:
(6*1)+(5*2)+(4*4)+(3*4)+(2*5)+(1*8)=62
62 % 10 = 2
So 1244-58-2 is a valid CAS Registry Number.
InChI:InChI=1/C22H30O4/c1-5-6-7-8-15-12-18(23)20(21(24)19(15)22(25)26)17-11-14(4)9-10-16(17)13(2)3/h11-12,16-17,23-24H,2,5-10H2,1,3-4H3,(H,25,26)/t16-,17+/m0/s1

1244-58-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name cannabidiolic acid

1.2 Other means of identification

Product number -
Other names Cannabidiolsaeure

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1244-58-2 SDS

1244-58-2Relevant articles and documents

CANNABINOID ACID ESTER COMPOSITIONS AND USES THEREOF

-

Paragraph 00409, (2021/02/26)

The present disclosure provides pharmaceutical compositions including a cannabinoid acid ester compound alone or in combination with one or more additional cannabinoid compounds. In some embodiments, the cannabinoid acid ester compound is a tetrahydrocann

CANNABIDIOLIC ACID (CBDA) DERIVATIVES AND USES THEREOF

-

Page/Page column 57, (2021/12/31)

The present invention provides novel compounds comprising cannabidiolic acid (CBDA) derivatives, including acids and esters, and uses thereof in the treatment of various diseases, disorders, conditions and symptoms.

CANNABIDIOLIC ACID ESTERS FOR TREATING MUSCULAR DYSTROPHY

-

Page/Page column 40; 41, (2021/07/10)

The present invention provides compositions and methods for treating muscular dystrophy. In particular, the present invention provides pharmaceutical compositions and formulations comprising a cannabidiolic acid (CBDA) ester alone or in combination with o

CANNABIDIOLIC ACID (CBDA) DERIVATIVES AND USES THEREOF

-

Page/Page column 45, (2021/12/31)

The present invention provides novel compounds comprising cannabidiolic acid (CBDA) derivatives, including acids and esters, and uses thereof in the treatment of various diseases, disorders, conditions and symptoms.

CANNABIDIOLIC ACID (CBDA) DERIVATIVES AND USES THEREOF

-

Page/Page column 50-51, (2021/12/31)

The present invention provides novel compounds comprising cannabidiolic acid (CBDA) derivatives, including acids and esters, and uses thereof in the treatment of various diseases, disorders, conditions and symptoms.

CANNABIDIOLIC ACID ESTERS FOR COSMETIC OR EDIBLE COMPOSITIONS

-

Page/Page column 38, (2020/07/15)

The present invention provides cosmetic or edible compositions comprising a cannabinoid component, wherein the cannabinoid component comprises a cannabidiolic acid (CBDA) ester alone or in combination with one or more cannabinoid compound(s), and a physio

CANNABINOID ACID ESTER COMPOSITIONS AND USES THEREOF

-

Paragraph 00345, (2020/09/30)

The present disclosure provides pharmaceutical compositions including a cannabinoid acid ester compound alone or in combination with one or more additional cannabinoid compounds. In some embodiments, the cannabinoid acid ester compound is a cannabidiolic

SYNTHESIS OF PHYTOCANNABINOIDS INCLUDING A DEMETHYLATION STEP

-

, (2019/03/05)

A method for demethylating a methylated phytocannabinoid compound of Formula I to form a phytocannabinoid compound of Formula II: Formula I Formula II wherein: R1 is selected from the group consisting of: substituted or unsubstituted C1-C5 alkyl; R2 is selected from the group consisting of: OH or O, and R3 is selected from the group consisting of: a substituted or unsubstituted cyclohexene, a substituted or unsubstituted C2-C8 alkene, or a substituted or unsubstituted C2-C8 dialkene; or R2 is O, and R2 and R3 together form a ring structure in which R2 is an internal ring atom; wherein the method includes: heating a reaction mixture comprising the methylated phytocannabinoid compounds and a polar aprotic solvent in the presence of a dissolved inorganic alkaline salt for a time sufficient to demethylate at least a portion of the methylated phytocannabinoid compounds and form the phytocannabinoid compound.

Cannabidiol intermediate and preparation method and application thereof

-

Paragraph 0043; 0052-0053; 0054; 0062-0063, (2019/05/21)

The invention discloses a cannabidiol intermediate and a preparation method and application thereof. A high-quality intermediate can be obtained by using trans-2-octenyl methyl ester and tert-butyl acetoacetate as raw materials through two-step reaction o

CANNABIDIOLIC ACID ESTERS COMPOSITIONS AND USES THEREOF

-

Paragraph 0062; 0063, (2019/01/10)

Cannabidiolic acid esters, compositions comprising them and uses thereof in the treatment of various diseases, conditions and symptoms.