Welcome to LookChem.com Sign In|Join Free

CAS

  • or

1257044-57-7

Post Buying Request

1257044-57-7 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier
  • methyl 2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)-4-(piperazin-1-yl)benzoate

    Cas No: 1257044-57-7

  • No Data

  • 1 Metric Ton

  • 1 million Metric Ton/Year

  • COLORCOM LTD.
  • Contact Supplier

1257044-57-7 Usage

Description

Methyl 2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)-4-(piperazin-1-yl)benzoate is a complex organic compound that features a methyl ester group attached to a 2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)-4-(piperazin-1-yl)benzoate moiety. This molecule is recognized for its potential as a drug candidate, with ongoing research into its pharmacological properties. It is hypothesized to have an affinity for specific receptors within the central nervous system, suggesting that it may be beneficial in the treatment of neurological disorders.

Uses

Used in Pharmaceutical Development:
Methyl 2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)-4-(piperazin-1-yl)benzoate is utilized as a potential therapeutic agent for neurological disorders due to its suspected receptor affinity within the central nervous system. Its precise mechanism of action and efficacy are subjects of ongoing research, with the aim of developing new treatments for various neurological conditions.
Used in Research and Development:
In the field of medicinal chemistry, this compound serves as a subject of research to explore its pharmacological profile and potential interactions with biological targets. Understanding its properties can contribute to the advancement of drug discovery and the development of novel therapeutics for neurological diseases.
Further research is essential to fully elucidate the potential uses and effects of methyl 2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)-4-(piperazin-1-yl)benzoate, ensuring that its applications are grounded in scientific evidence and aligned with the needs of patients and healthcare providers.

Check Digit Verification of cas no

The CAS Registry Mumber 1257044-57-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,5,7,0,4 and 4 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1257044-57:
(9*1)+(8*2)+(7*5)+(6*7)+(5*0)+(4*4)+(3*4)+(2*5)+(1*7)=147
147 % 10 = 7
So 1257044-57-7 is a valid CAS Registry Number.

1257044-57-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name Methyl 2-[(1H-pyrrolo[2,3-b]pyridin-5-yl)oxy]-4-(piperazin-1-yl)benzoate

1.2 Other means of identification

Product number -
Other names methyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(piperazin-1-yl)benzoate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1257044-57-7 SDS

1257044-57-7Downstream Products

1257044-57-7Relevant articles and documents

Potential applications of BPFP1 in Bcl-2 protein quantification, carcinoma cell visualization, cell sorting and early cancer diagnosis

Fang, Hao,Hou, Xuben,Li, Jia,Liang, Tao,Yang, Xinying,Zhou, Yi

, (2021/08/12)

Overexpression of the Bcl-2 protein has emerged as a hallmark of carcinoma cells and can be employed as a biochemical biomarker of these cells. Therefore, some Bcl-2 protein fluorescence probes (BPFPs) were designed for Bcl-2 protein quantification and carcinoma cells labeling. The high Bcl-2 protein binding affinity (Ki a range of concentrations of Bcl-2 protein, BPFP1 exhibited the desired fluorescence properties and its fluorescence intensity is proportional to Bcl-2 protein concentration. Therefore, BPFP1 provides a convenient approach for Bcl-2 protein quantification and we could determine the concentration of Bcl-2 protein based on the BPFP1's fluorescence intensity. Subsequent studies revealed that BPFP1 can fluorescently label carcinoma cells by binding to overexpressed Bcl-2 protein in living cells, and can distinguish carcinoma cells (HL-60 cells and ACHN cells) from normal-tissue cells (HUVECs) according to the different Bcl-2 protein expression levels between carcinoma cells and normal tissue cells. In the present study, BPFP1 represents a new tool for Bcl-2 protein quantification, carcinoma cell visualization and cell sorting. Moreover, BPFP1 can be used in the future for early cancer diagnosis by detecting carcinoma cells in patient tissues.

Preparation method of Venetoclax intermediate

-

Paragraph 0012, (2019/12/29)

The invention belongs to the field of medicinal chemistry. The invention mainly relates to a preparation method of a Venetoclax intermediate (I) methyl-2-(1H-pyrrole [2, 3-B] pyridine-5-oxy)-4-(piperazine-1-yl) benzoate. The preparation method comprises t

PROCESS FOR THE PREPARATION OF VENETOCLAX

-

Page/Page column 6, (2018/03/06)

The present disclosure provides novel synthetic process for the preparation of venetoclax. The disclosed processes involve the use of novel intermediates. Processes for the preparation of these intermediates are also disclosed as well as methods for the preparation of particularly useful salts thereof.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 1257044-57-7