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126502-17-8

N(6)-methyl-2',3'-dideoxy-2'-fluoro-beta-arabinofuranosyladenine is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 126502-17-8 Structure

  • Basic information

    1. Product Name: N(6)-methyl-2',3'-dideoxy-2'-fluoro-beta-arabinofuranosyladenine
    2. Synonyms: N(6)-methyl-2',3'-dideoxy-2'-fluoro-beta-arabinofuranosyladenine
    3. CAS NO:126502-17-8
    4. Molecular Formula: C11H14FN5O2
    5. Molecular Weight: 267.2595632
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 126502-17-8.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 526°Cat760mmHg
    3. Flash Point: 271.9°C
    4. Appearance: /
    5. Density: 1.67g/cm3
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: N(6)-methyl-2',3'-dideoxy-2'-fluoro-beta-arabinofuranosyladenine(CAS DataBase Reference)
    10. NIST Chemistry Reference: N(6)-methyl-2',3'-dideoxy-2'-fluoro-beta-arabinofuranosyladenine(126502-17-8)
    11. EPA Substance Registry System: N(6)-methyl-2',3'-dideoxy-2'-fluoro-beta-arabinofuranosyladenine(126502-17-8)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 126502-17-8(Hazardous Substances Data)

126502-17-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 126502-17-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,6,5,0 and 2 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 126502-17:
(8*1)+(7*2)+(6*6)+(5*5)+(4*0)+(3*2)+(2*1)+(1*7)=98
98 % 10 = 8
So 126502-17-8 is a valid CAS Registry Number.

126502-17-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name N6-methyl-9-(2',3'-dideoxy-2'-fluoro-β-D-arabinofuranosyl)adenine

1.2 Other means of identification

Product number -
Other names N6-methyl-9-(2,3-dideoxy-2-fluoro-β-D-arabinofuranosyl)adenine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:126502-17-8 SDS

126502-17-8Relevant articles and documents

In vitro and in vivo evaluation of 6-azido-2',3'-dideoxy-2'-fluoro-β- D-arabinofuranosylpurine and N6-methyl-2',3'-dideoxy-2'-fluoro-β-D- arabinofuranosyladenine as prodrugs of the anti-HIV nucleosides 2'-F-ara-ddA and 2'-F-ara-ddI

Koudriakova, Tanya,Manouilov, Konstantine K.,Shanmuganathan, Kirupa,Kotra, Lakshmi P.,Boudinot, F.Douglas,Cretton-Scott, Erica,Sommadossi, Jean-Pierre,Schinazi, Raymond F.,Chu, Chung K.

, p. 4676 - 4681 (1996)

In an effort to improve the pharmacokinetic properties and tissue distribution of 2'-F-ara-ddI, two lipophilic prodrugs, 6-azido-2',3'-dideoxy- 2'-fluoro-β-D-arabinofuranosylpurine (FAAddP, 4) and N6-methyl-2',3'- dideoxy-2'-fluoro-β-D-arabinof

Lipophilic, acid-stable, adenosine deaminase-activated anti-HIV prodrugs for central nervous system delivery. 3. 6-amino prodrugs of 2′-β-fluoro-2′,3′-dideoxyinosine

Driscoll, John S.,Siddiqui, Maqbool A.,Ford Jr., Harry,Kelley, James A.,Roth, Jeri S.,Mitsuya, Hiroaki,Tanaka, Masatoshi,Marquez, Victor E.

, p. 1619 - 1625 (2007/10/03)

A series of 6-substituted amino analogs of 9-(2,3-dideoxy-2-fluoro-β-D-threo-pentofuranosyl) purines (F-ddN) has been synthesized and characterized with the objective of finding compounds which might be superior to existing drugs for the treatment of HIV

2'-fluorofuranosyl derivatives and novel method of preparing 2'-fluoropyrimidine and 2'-fluoropurine nucleosides

-

, (2008/06/13)

A compound has the formula STR1 wherein R is selected from the group consisting of (C7 -C20)aroyl, (C6 -C20)aryl, aralkyl and alkylaryl, and (C1 -C10)alkyl-di(C6 -C20)aryl Si, R' is selected from the group consisting of (C1 -C10)alkyl, (C7 -C20)aroyl and (C2 -C12)acyl, all of which may be further substituted with O, S, N or alkyl, and R'" is selected from the group consisting of halogen, (C1 -C10)alkoxy, (C1 -C10)acyloxy, O-methane-sulfonyl and O-p-toluenesulfonyl. A composition of matter comprises 0.001 to 99.999 wt % of the above compound.

Potential Anti-AIDS Drugs. Lipophilic, Adenosine Deaminase-Activated Prodrugs

Barchi, Joseph J.,Marquez, Victor E.,Driscoll, John S.,Ford, Harry,Mitsuya, Hiroaki,et al.

, p. 1647 - 1655 (2007/10/02)

Selected acid-stable (2'-fluoro-2',3'-dideoxyarabinofuranosyl)adenine nucleosides containing methyl groups and other lipophilic functions at various positions in the adenine ring were prepared and evaluated as anti-HIV agents.The N6-methyl (1f)

Synthesis and Structure-Activity Relationships of 6-Substituted 2',3'-Dideoxypurine Nucleosides as Potential Anti-Human Immunodeficiency Virus Agents

Chu, Chung K.,Ullas, Giliyar V.,Jeong, Lak S.,Ahn, Soon K.,Doboszewski, Bogdan,et al.

, p. 1553 - 1561 (2007/10/02)

In order to study the structure-activity relationships of 2',3'-dideoxypurine nucleosides as potential anti-HIV agents, various 6-substituted purine analogues have been synthesized and examined in virus-infected and uninfected human peripheral blood monon

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