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143-70-4

Morphinan-3,6-diol,7,8-didehydro-4,5-epoxy-17-methyl-, (5a,6b)- (9CI) is a complex organic compound belonging to the morphinan class, which is derived from the opium poppy plant. This specific compound is characterized by its unique molecular structure, featuring a 3,6-diol group, a 7,8-didehydro group, a 4,5-epoxy group, and a 17-methyl group. The compound is also known by its IUPAC name, which provides a systematic way to describe its structure. It is important to note that this compound is a synthetic derivative and not naturally occurring. Due to its complex structure and potential pharmacological properties, it is typically studied in the context of medicinal chemistry and drug development. However, it is crucial to approach such compounds with caution, as they may have psychoactive effects and potential for abuse, similar to other morphinan derivatives.

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  • Morphinan-3,6-diol,7,8-didehydro-4,5-epoxy-17-methyl-, (5a,6b)- (9CI)

    Cas No: 143-70-4

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  • 143-70-4 Structure

  • Basic information

    1. Product Name: Morphinan-3,6-diol,7,8-didehydro-4,5-epoxy-17-methyl-, (5a,6b)- (9CI)
    2. Synonyms: Morphinan-3,6b-diol, 7,8-didehydro-4,5a-epoxy-17-methyl- (8CI);6-Isomorphine; Isomorphine; a-Isomorphine
    3. CAS NO:143-70-4
    4. Molecular Formula: C17H19 N O3
    5. Molecular Weight: 285.343
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 143-70-4.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 476.2°Cat760mmHg
    3. Flash Point: 241.8°C
    4. Appearance: N/A
    5. Density: 1.44g/cm3
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: Morphinan-3,6-diol,7,8-didehydro-4,5-epoxy-17-methyl-, (5a,6b)- (9CI)(CAS DataBase Reference)
    10. NIST Chemistry Reference: Morphinan-3,6-diol,7,8-didehydro-4,5-epoxy-17-methyl-, (5a,6b)- (9CI)(143-70-4)
    11. EPA Substance Registry System: Morphinan-3,6-diol,7,8-didehydro-4,5-epoxy-17-methyl-, (5a,6b)- (9CI)(143-70-4)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 143-70-4(Hazardous Substances Data)

143-70-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 143-70-4 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,4 and 3 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 143-70:
(5*1)+(4*4)+(3*3)+(2*7)+(1*0)=44
44 % 10 = 4
So 143-70-4 is a valid CAS Registry Number.

143-70-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name morphine

1.2 Other means of identification

Product number -
Other names Morphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-methyl-, (5α,6β)-

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:143-70-4 SDS

143-70-4Relevant articles and documents

Method for catalyzing asymmetric synthesis of codeine and morphine

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Paragraph 0066; 0110-0112, (2019/05/02)

The invention discloses a method for synthesizing codeine and morphine. The method comprises the following steps: (I) taking 3-butyne-1-alcohol as a starting raw material to synthesize a compound 6: (shown in the description) (II) compound 6 firstly has intramolecular Michael addition reaction under the catalysis of a spirocyclic amine catalyst, and then acid is added to perform the dehydration cyclization reaction to obtain a chiral compound 7 with a hydrogenated dibenzofuran structure: (shown in the description) (III) the compound 7 has allylation, ozone oxidation, Foucault reaction, epoxidation, Wharton oxygen transfer reaction, debenzylation, Mitsunobu reaction, DMP oxidation, and the conversion by virtue of the reduction of sodium borohydride and Birch reduction to obtain the codeine(shown in the description). Under the action of boron tribromide, the methyl protecting group is removed from the codeine to obtain morphine. Compared with the existing synthesis method, the total synthesis method of the invention is simpler, and the catalytic asymmetric reaction has the advantages of high enantioselectivity, high yield and the like.

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