14316-14-4

Basic information

• Product Name: N-(2-Hydroxyethyl)-4-methylbenzenesulfonamide
• Synonyms: N-(2-Hydroxyethyl)-4-methylbenzenesulfonamide;N-(2-Hydroxyethyl)-4-toluenesulfonaMide
• CAS NO: 14316-14-4
• Molecular Formula: C₉H₁₃NO₃S
• Molecular Weight: 215.26942
• Product Categories: Aromatics;Sulfur & Selenium Compounds
• Mol File: 14316-14-4.mol
• Article Data: 54

Chemical Properties

• Melting Point: 55-57°C
• Boiling Point: 380.2 °C at 760 mmHg
• Flash Point: 183.8 °C
• Appearance: /
• Density: 1.263 g/cm³
• Vapor Pressure: 1.85E-06mmHg at 25°C
• Refractive Index: 1.554
• Storage Temp.: Refrigerator
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• CAS DataBase Reference: N-(2-Hydroxyethyl)-4-methylbenzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-Hydroxyethyl)-4-methylbenzenesulfonamide(14316-14-4)
• EPA Substance Registry System: N-(2-Hydroxyethyl)-4-methylbenzenesulfonamide(14316-14-4)

Safety Data

• Hazardous Substances Data: 14316-14-4(Hazardous Substances Data)

Usage

Chemical Properties

Off-White Solid

Uses

N-(2-Hydroxyethyl)-4-methylbenzenesulfonamide (cas# 14316-14-4) is a compound useful in organic synthesis.

InChI:InChI=1/C9H13NO3S/c1-8-2-4-9(5-3-8)14(12,13)10-6-7-11/h2-5,10-11H,6-7H2,1H3

Upstream product

• 75-21-8 oxirane 
• 70-55-3 toluene-4-sulfonamide 
• 141-43-5 ethanolamine 
• 2232-08-8 N-tosylimidazole 
• 1219601-57-6 1-(p-tolylsulfonyl)triazole 
• 57483-27-9 N-(2-oxoethyl)-4-methylbenzenesulfonamide 
• 107-09-5 2-bromoethylamine 
• 98-59-9 p-toluenesulfonyl chloride 
• 98-09-9 benzenesulfonyl chloride 
• 110-63-4 Butane-1,4-diol 
• 142-26-7 2-acetylaminoethanol 
• 17455-13-9 18-crown-6 ether 
• 107-07-3 2-chloro-ethanol 
• 64-17-5 ethanol 

Downstream Products

• 50977-94-1 N,N'-di(para-toluensulfonyl)-3,9-diaza-6-oxaundecane-1,11-diol 
• 173602-05-6 3-propanal dimethyl acetal 
• 70509-21-6 2-phenyl-3-tosyloxazolidine 
• 1119121-89-9 N-(2-hydroxyethyl)-4-methyl-N-(3-methylbut-2-en-1-yl)-benzenesulfonamide 
• 1579963-99-7 (2E,4E)-methyl 6-(N-(2-((tert-butyldimethylsilyl)oxy)ethyl)-4-methylphenyl-sulfonamido)hexa-2,4-dienoate 
• 1579963-97-5 (2E,4E)-methyl 6-(N-(2-hydroxyethyl)-4-methylphenylsulfonamido)hexa-2,4-dienoate 
• 1579963-67-9 (2E,4E)-methyl 6-(4-methyl-N-(2-oxoethyl)phenylsulfonamido)hexa-2,4-dienoate 
• 1579963-68-0 (E)-methyl 4-(4-oxo-1-tosylpyrrolidin-3-yl)but-2-enoate 
• 32121-04-3 N-cinnamyl-4-methylbenzenesulfonamide 
• 86553-38-0 1-[(4-methylphenyl)sulfonyl]-2-benzylpyrrolidine 

Relevant articles and documents

Synthesis and crystal structures of multifunctional tosylates as basis for star-shaped poly(2-ethyl-2-oxazoline)s

The synthesis of well-defined polymer architectures is of major importance for the development of complex functional materials. In this contribution, we discuss the synthesis of a range of multifunctional star-shaped tosylates as potential initiators for the living cationic ring-opening polymerization (CROP) of 2-oxazolines resulting in star-shaped polymers. The synthesis of the tosylates was performed by esterification of the corresponding alcohols with tosyl chloride. Recrystallization of these tosylate compounds afforded single crystals, and the X-ray crystal structures of di-, tetra-and hexa-tosylates are reported. The use of tetra-and hexatosylates, based on (di)pentaerythritol as initiators for the CROP of 2-ethyl-2-oxazoline, resulted in very slow initiation and illdefined polymers, which is most likely caused by steric hindrance in these initiators. As a consequence, a porphyrin-cored tetratosylate initiator was prepared, which yielded a well-defined star-shaped poly(2-ethyl-2-oxazoline) by CROP as demonstrated by SEC with RI, UV and diode-array detectors, as well as by 1H NMR spectroscopy.

Dual Nickel- And Photoredox-Catalyzed Reductive Cross-Coupling to Access Chiral Trifluoromethylated Alkanes

A dual nickel/photoredox-catalyzed enantioselective reductive cross-coupling of aryl halides with CF3-substituted racemic alkyl electrophiles has been established. The approach accommodates a broad palette of aryl iodides and alkyl bromides to access a va

Copper-catalyzed enantioselective alkene carboetherification for the synthesis of saturated six-membered cyclic ethers

The enantioselective copper-catalyzed oxidative coupling of alkenols with styrenes for the construction of dihydropyrans, isochromans, pyrans and morpholines is reported. A concise formal synthesis of a σ1receptor ligand using this alkene carbo