1562-31-8

Basic information

• Product Name: Ethenesulfonic acid methyl ester
• Synonyms: Ethenesulfonic acid methyl ester;Methyl ethenesulfonate;Methyl ethylenesulfonate
• CAS NO: 1562-31-8
• Molecular Formula: C₃H₆O₃S
• Molecular Weight: 122.14
• Mol File: 1562-31-8.mol
• Article Data: 4

Chemical Properties

• Melting Point: 114.5-115.6 °C
• Boiling Point: 84-85 °C(Press: 12 Torr)
• Appearance: /
• Density: 1.214±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Ethenesulfonic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Ethenesulfonic acid methyl ester(1562-31-8)
• EPA Substance Registry System: Ethenesulfonic acid methyl ester(1562-31-8)

Safety Data

• Hazardous Substances Data: 1562-31-8(Hazardous Substances Data)

Usage

General Description

Ethenesulfonic acid methyl ester, also known as methyl vinyl sulfonate, is a chemical compound with the molecular formula C3H6O3S. It is a colorless liquid with a pungent odor, and it is highly reactive due to the presence of a double bond. Ethenesulfonic acid methyl ester is commonly used as a reagent in organic synthesis and as a monomer in the production of polymers such as polyvinylsulfonate, which is used in a variety of industrial applications. It is also used in the synthesis of pharmaceuticals and agrochemicals. However, it is important to handle this compound with caution as it is a strong alkylating agent and can cause severe skin and eye irritation. Additionally, it is toxic if ingested or inhaled and can cause respiratory and other health issues if proper precautions are not taken.

Upstream product

• 110-86-1 pyridine 
• 67-56-1 methanol 
• 75-09-2 dichloromethane 
• 1622-32-8 2-Chloroethanesulfonyl chloride 
• 54429-56-0 2-bromoethanesulfonyl chloride 
• 1071562-91-8 2-chloroethenesulfonyl chloride 
• 124-41-4 sodium methylate 
• 186581-53-3 diazomethane 
• 1184-84-5 ethenesulfonic acid 

Downstream Products

• 33831-89-9 methyl cyclohex-3-ene-1-sulfonate 
• 13217-58-8 2-Methoxysulfonyl-1,4-diphenyl-naphthalin 
• 1184-84-5 ethenesulfonic acid 
• 33831-91-3 4-(2,4-Dichlorphenoxysulfonyl)-cyclohex-1-en 
• 33831-90-2 4-(4-Chlorphenoxysulfonyl)-cyclohex-1-en 
• 33912-50-4 4-Phenoxysulfonyl-cyclohex-1-en 
• 28509-37-7 β-Cumylperoxyethansulfonsaeuremethylester 

Relevant articles and documents

Controlled synthesis of sulfonated block copolymers having thermoresponsive property by RAFT polymerization of vinyl sulfonate esters

Four vinyl sulfonate ester derivatives, methyl ethenesulfonate (MES), ethyl ethenesulfonate (EES), 2,2,2-trifluoroethyl ethenesulfonate (TFES), and 2,2,2-trichloroethyl ethenesulfonate (TCLES), which are protected forms of vinyl sulfonic acids, were polymerized by reversible addition-fragmentation chain transfer (RAFT) polymerization. Polymers having relatively narrow molecular weight distributions and pre-determined molecular weights were obtained by the polymerization of all monomers using a suitable xanthate-type chain transfer agent (CTA). The RAFT polymerizations of EES and TCLES were found to proceed in controlled fashions under suitable conditions, as confirmed by the formation of narrow polydispersity products, molecular weights controlled by the monomer/chain transfer agent ratio, and linear increases in molecular weight with conversion. Deprotection of the ethyl group of poly(EES) by LiBr in refluxing 2-butanone proceeded smoothly to give water-soluble poly(lithium vinyl sulfonate). Poly(potassium vinyl sulfonate) was also obtained by the deprotection of poly(TCLES) using potassium tert-butoxide. The syntheses of thermoresponsive block copolymers involving poly(lithium vinyl sulfonate) segments were conducted by RAFT polymerization of N-isopropylacrylamide using poly(EES) macro-CTA, followed by deprotection. The thermally-induced phase separation behavior and assembled structures of the block copolymers were also studied in aqueous solution.

A novel potent nicotinamide phosphoribosyltransferase inhibitor synthesized via click chemistry

The inhibition of NAD synthesis or salvage pathways has been proposed as a novel target for antitumoral drugs. Two molecules with this mechanism of action are at present undergoing clinical trials. In searching for similar novel molecules, we exploited co