1562-31-8

Basic information

• Product Name: Ethenesulfonic acid methyl ester
• Synonyms: Ethenesulfonic acid methyl ester;Methyl ethenesulfonate;Methyl ethylenesulfonate
• CAS NO: 1562-31-8
• Molecular Formula: C₃H₆O₃S
• Molecular Weight: 122.14
• Mol File: 1562-31-8.mol

Chemical Properties

• Melting Point: 114.5-115.6 °C
• Boiling Point: 84-85 °C(Press: 12 Torr)
• Appearance: /
• Density: 1.214±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Ethenesulfonic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Ethenesulfonic acid methyl ester(1562-31-8)
• EPA Substance Registry System: Ethenesulfonic acid methyl ester(1562-31-8)

Safety Data

• Hazardous Substances Data: 1562-31-8(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
Ethenesulfonic acid methyl ester is used as a reagent in organic synthesis for its ability to participate in various chemical reactions, contributing to the formation of a wide range of organic compounds.
Used in Polymer Production:
In the polymer industry, Ethenesulfonic acid methyl ester serves as a monomer in the production of polymers such as polyvinylsulfonate. This polymer finds applications in different sectors due to its unique properties.
Used in Pharmaceutical Synthesis:
Ethenesulfonic acid methyl ester is utilized as a key intermediate in the synthesis of pharmaceuticals, playing a crucial role in the development of new drugs and medicinal compounds.
Used in Agrochemical Synthesis:
Ethenesulfonic acid methyl ester is also employed in the synthesis of agrochemicals, contributing to the creation of products that are vital for agricultural applications.
Safety Precautions:
It is imperative to handle Ethenesulfonic acid methyl ester with care, as it is a strong alkylating agent that can cause severe skin and eye irritation. Moreover, it is toxic if ingested or inhaled, posing risks of respiratory and other health issues. Adequate safety measures and precautions should be taken to mitigate these risks during its use in various applications.

Upstream product

• 186581-53-3 diazomethane 
• 1184-84-5 ethenesulfonic acid 
• 110-86-1 pyridine 
• 67-56-1 methanol 
• 75-09-2 dichloromethane 
• 1622-32-8 2-Chloroethanesulfonyl chloride 
• 54429-56-0 2-bromoethanesulfonyl chloride 
• 124-41-4 sodium methylate 
• 1071562-91-8 2-chloroethenesulfonyl chloride 

Downstream Products

• 28509-37-7 β-Cumylperoxyethansulfonsaeuremethylester 
• 33912-50-4 4-Phenoxysulfonyl-cyclohex-1-en 
• 33831-90-2 4-(4-Chlorphenoxysulfonyl)-cyclohex-1-en 
• 33831-91-3 4-(2,4-Dichlorphenoxysulfonyl)-cyclohex-1-en 
• 1184-84-5 ethenesulfonic acid 
• 13217-58-8 2-Methoxysulfonyl-1,4-diphenyl-naphthalin 
• 33831-89-9 methyl cyclohex-3-ene-1-sulfonate 

Relevant articles and documents

Controlled synthesis of sulfonated block copolymers having thermoresponsive property by RAFT polymerization of vinyl sulfonate esters

Four vinyl sulfonate ester derivatives, methyl ethenesulfonate (MES), ethyl ethenesulfonate (EES), 2,2,2-trifluoroethyl ethenesulfonate (TFES), and 2,2,2-trichloroethyl ethenesulfonate (TCLES), which are protected forms of vinyl sulfonic acids, were polymerized by reversible addition-fragmentation chain transfer (RAFT) polymerization. Polymers having relatively narrow molecular weight distributions and pre-determined molecular weights were obtained by the polymerization of all monomers using a suitable xanthate-type chain transfer agent (CTA). The RAFT polymerizations of EES and TCLES were found to proceed in controlled fashions under suitable conditions, as confirmed by the formation of narrow polydispersity products, molecular weights controlled by the monomer/chain transfer agent ratio, and linear increases in molecular weight with conversion. Deprotection of the ethyl group of poly(EES) by LiBr in refluxing 2-butanone proceeded smoothly to give water-soluble poly(lithium vinyl sulfonate). Poly(potassium vinyl sulfonate) was also obtained by the deprotection of poly(TCLES) using potassium tert-butoxide. The syntheses of thermoresponsive block copolymers involving poly(lithium vinyl sulfonate) segments were conducted by RAFT polymerization of N-isopropylacrylamide using poly(EES) macro-CTA, followed by deprotection. The thermally-induced phase separation behavior and assembled structures of the block copolymers were also studied in aqueous solution.

PRODUCTION METHOD FOR SULTONE DERIVATIVES

There is provided a means to produce industrially a highly pure 2-hydroxy-4-oxa-5-thiatricyclo[4.2.1.03,7]nonane 5,5-dioxide derivative in high yield from highly pure and industrially available raw materials. The production method for a sultone derivative of the present invention comprises a step (A) to obtain a sulfonic acid derivative by hydrolyzing a sulfonyl halide derivative represented by the following chemical formula 1: or an enantiomer thereof and a step (B) to obtain a corresponding sultone derivative represented by the following chemical formula 2: or an enantiomer thereof by treating the sulfonic acid derivative with a oxidizing agent.

A novel potent nicotinamide phosphoribosyltransferase inhibitor synthesized via click chemistry

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