16423-51-1Relevant articles and documents
Preparation of mixed carbamic/dithiocarbamic anhydrides via silyl carbamates or silyl dithiocarbamates
Kardon, Ferenc,Moertl, Maria,Magyarfalvi, Gabor
, p. 192 - 199 (2008)
The reactions of silyl carbamates and silyl dithiocarbamates with different acid chlorides (carbamoyl/thiocarbamoyl chloride, chloroformates, etc.) have been studied. The obtained mixed anhydrides have different thermal stability. Copyright Taylor & Francis Group, LLC.
Using dialkyl amide: Via forming hydrophobic deep eutectic solvents to separate citric acid from fermentation broth
Liu, Lijuan,Wei, Qifeng,Zhou, Yong,Ren, Xiulian
supporting information, p. 2526 - 2533 (2020/05/13)
Nowadays, developing appropriate technology is one of the biggest challenges for society to reduce environmental impact. In this research, to avoid the traditional calcium salt method which produces a large amount of waste gypsum residue, a new way of separating citric acid from fermentation broth was developed by forming hydrophobic deep eutectic solvents (DESs), in which amide and citric acid were used as the hydrogen bond acceptor and donor respectively when amide was in contact with the fermentation broth containing citric acid. Among these amides, C10H21NO was found to be an efficient hydrogen bond acceptor forming hydrophobic DESs with the citric acid based on the molecular size and shape and has the largest hydrophobic equilibrium constant of 3.14. The hydrophobic DES formation mechanism was studied by analyzing the chemical bonds using FT-IR and quantum chemical (QC) calculations. C10H21NO was regenerated by elevating the temperature of the hydrophobic DESs. The regenerated C10H21NO exhibited good recycling properties with no obvious reduction of the ability to form hydrophobic DESs. This effective way of obtaining high-quality citric acids provides new ideas for the separation of other carboxylic acids.
The selective reaction of primary amines with carbonyl imidazole containing compounds: Selective amide and carbamate synthesis
Rannard, Steve P.,Davis, Nicola J.
, p. 2117 - 2120 (2007/10/03)
matrix presented A new highly selective synthesis of amides and carbamates is described. In both cases the syntheses involve the formation of carbonyl imidazole intermediates which subsequently undergo previously unreported selective reactions with primary amines. Acid imidazolides with sufficient chain length will exclusively react with primary amines even in the presence of secondary and tertiary functionality. The imidazole carboxylic esters of secondary or tertiary alcohols also react selectively with primary amines, forming controlled carbamate structures.
Nucleophilic Attack at Heterocyclic Nitrogen: Unusual Reactivity of the Benzotriazole Heterocyclic Ring
Katritzky, Alan R.,Rachwal, Stanislaw,Offerman, Rick J.,Najzarek, Zbigniew,Yagoub, Ahmed K.,Zhang Yongmin
, p. 1545 - 1551 (2007/10/02)
Grignard reagents attack 1-imidoylbenzotriazoles at the imidoyl carbon atom and also at the benzotriazolyl N-2 and N-3 atoms leading to complex reaction mixtures, the composition of which allowed identification of the main reaction paths.Mechanisms are discussed.Previous examples of nucleophilic attack on pyridine-like nitrogen atoms are reviewed.The 1-imidoylbenzotriazoles were prepared from amides with benzotriazole and phosphoryl chloride.Amides derived from secondary amines give α-(benzotriazol-1-yl)enamines.
