n,n-Dihexylacetamide

Base Information

• Chemical Name: n,n-Dihexylacetamide
• CAS No.: 16423-51-1
• Molecular Formula: C14H29 N O
• Molecular Weight: 227.39
• Hs Code.: 2924199090
• European Community (EC) Number: 662-138-3
• NSC Number: 137920,54296
• DSSTox Substance ID: DTXSID00288129
• Nikkaji Number: J2.620.867J
• Wikidata: Q82024421
• Mol file: 16423-51-1.mol

Synonyms:n,n-dihexylacetamide;16423-51-1;N,N-Di-n-hexylacetamide;Acetamide, N,N-dihexyl-;N-Dihexyl-acetamid;NSC54296;SCHEMBL1858068;DTXSID00288129;JFUCOPIALLYRGN-UHFFFAOYSA-N;MFCD00082658;NSC-54296;NSC137920;AKOS003867504;NSC-137920;SB80152;DS-15083;143-16-8, Ac;CS-0152143;FT-0629575;FT-0629576;D82003;(3-Bromopyridin-4-yl)carbamicacidtert-butylester

Chemical Property of n,n-Dihexylacetamide

Chemical Property:

• Vapor Pressure: 0.00289mmHg at 25°C
• Refractive Index: 1.4490
• Boiling Point: 284.9°Cat760mmHg
• Flash Point: 106°C
• PSA: 20.31000
• Density: 0.861g/cm³
• LogP: 3.99550
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 4.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 10
• Exact Mass: 227.224914549
• Heavy Atom Count: 16
• Complexity: 156

Purity/Quality:

97% ^*data from raw suppliers

N,N-DIHEXYLACETAMIDE Aldrich ^*data from reagent suppliers

Safty Information:

• Safety Statements: S24/25:Avoid contact with skin and eyes.

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCN(CCCCCC)C(=O)C

Technology Process of n,n-Dihexylacetamide

There total 5 articles about n,n-Dihexylacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Hexylmagnesiumiodid (89583-95-9) + acetyl chloride (75-36-5) → 1-iodo-5-hexanone (4367-98-0) + N,N-dihexylacetamide (16423-51-1) + Acetanilid (103-84-4)

Guidance literature:

With N-[1-(benzotriazol-1-yl)ethylidene]aniline; Yield given. Multistep reaction. Yields of byproduct given; 1.) THF, ether, 25 deg C, 16 h, 2.) 25 deg C, 1 h;

Reference yield:

dihexylamine (143-16-8) + acetic anhydride (108-24-7) → N,N-dihexylacetamide (16423-51-1)

Guidance literature:

DOI:10.1021/ja01614a028

Reference yield:

N-Acetylimidazole (2466-76-4) + dihexylamine (143-16-8) → N,N-dihexylacetamide (16423-51-1)

Guidance literature:

In toluene;

DOI:10.1021/ol006020n

upstream raw materials:

dihexylamine

acetic anhydride

Hexylmagnesiumiodid

acetyl chloride

Downstream raw materials:

N-nitrodihexylamine