166953-64-6 Usage
Description
BENZYL 4-BROMOTETRAHYDRO-1(2H)-PYRIDINECARBOXYLATE is a chemical compound belonging to the pyridinecarboxylate class, characterized by its molecular formula C14H16BrNO2. It is a white to off-white crystalline powder that serves as a crucial pharmaceutical intermediate, playing a significant role in the synthesis of various pharmaceutical drugs.
Used in Pharmaceutical Industry:
BENZYL 4-BROMOTETRAHYDRO-1(2H)-PYRIDINECARBOXYLATE is used as a pharmaceutical intermediate for the production of active pharmaceutical ingredients (APIs). Its potential biological activity and importance as a building block in the synthesis of many pharmaceuticals make it a valuable component in drug development.
Check Digit Verification of cas no
The CAS Registry Mumber 166953-64-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,6,9,5 and 3 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 166953-64:
(8*1)+(7*6)+(6*6)+(5*9)+(4*5)+(3*3)+(2*6)+(1*4)=176
176 % 10 = 6
So 166953-64-6 is a valid CAS Registry Number.
InChI:InChI=1/C13H16BrNO2/c14-12-6-8-15(9-7-12)13(16)17-10-11-4-2-1-3-5-11/h1-5,12H,6-10H2
166953-64-6Relevant articles and documents
Copper-Catalyzed Reductive Cross-Coupling of Nonactivated Alkyl Tosylates and Mesylates with Alkyl and Aryl Bromides
Liu, Jing-Hui,Yang, Chu-Ting,Lu, Xiao-Yu,Zhang, Zhen-Qi,Xu, Ling,Cui, Mian,Lu, Xi,Xiao, Bin,Fu, Yao,Liu, Lei
supporting information, p. 15334 - 15338 (2016/02/18)
A copper-catalyzed reductive cross-coupling reaction of nonactivated alkyl tosylates and mesylates with alkyl and aryl bromides was developed. It provides a practical method for efficient and cost-effective construction of aryl-alkyl and alkyl-alkyl C=C bonds with stereocontrol from readily available substrates. When used in an intramolecular fashion, the reaction enables convenient access to various substituted carbo- or heterocycles, such as 2,3-dihydrobenzofuran and benzochromene derivatives.
1-(4-PIPERIDINYL) BENZIMIDAZOLONES AS HISTAMINE H3 ANTAGONISTS
-
Page 44-45, (2010/02/04)
Disclosed are histamine H3 antagonists of the formula (I) wherein R1 is benzimidazolone derivative, M1 and M2 are optionally substituted carbon or nitrogen, R2 includes optionally substituted aryl or heteroaryl, and the remaining variables are as defined