169205-93-0 Usage
Uses
Used in Pharmaceutical Synthesis:
N-(3-HYDROXY-PYRIDIN-4-YL)-2,2-DIMETHYL-PROPIONAMIDE is used as a key intermediate in the synthesis of various pharmaceutical compounds, primarily due to its unique chemical structure that allows for the development of drugs targeting central nervous system disorders.
Used in Drug Development for Neurological and Psychiatric Conditions:
In the field of medicinal chemistry, N-(3-HYDROXY-PYRIDIN-4-YL)-2,2-DIMETHYL-PROPIONAMIDE is employed as a building block for the creation of drugs that have potential applications in the treatment of neurological and psychiatric conditions. Its role in drug development is crucial for enhancing the therapeutic options available for such conditions.
Used in Medicinal Chemistry Research:
N-(3-HYDROXY-PYRIDIN-4-YL)-2,2-DIMETHYL-PROPIONAMIDE is utilized as a valuable tool in medicinal chemistry research, where its properties are explored and harnessed to innovate new drug candidates and improve existing ones, thereby contributing to advancements in the field of pharmaceuticals and healthcare.
Check Digit Verification of cas no
The CAS Registry Mumber 169205-93-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,9,2,0 and 5 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 169205-93:
(8*1)+(7*6)+(6*9)+(5*2)+(4*0)+(3*5)+(2*9)+(1*3)=150
150 % 10 = 0
So 169205-93-0 is a valid CAS Registry Number.
InChI:InChI=1/C10H14N2O2/c1-10(2,3)9(14)12-7-4-5-11-6-8(7)13/h4-6,13H,1-3H3,(H,11,12,14)
169205-93-0Relevant articles and documents
Non-imidazole histamine H3 ligands. Part III. New 4-n-propylpiperazines as non-imidazole histamine H3-antagonists
Walczyski, Krzysztof,Zuiderveld, Obbe P.,Timmerman, Henk
, p. 15 - 23 (2005)
In search for a new lead of non-imidazole histamine H3-receptor antagonists, a series of 1[(2-thiazolopyridine)-4-n-propyl]piperazines, the analogous 1-[(2-oxazolopyridine)-4-npropyl]piperazines, 1-[(2-benzothiazole)-4- n-propyl]piperazine and 1-[(2-benzooxazole)4-n-propyl]piperazine were prepared and in vitro tested as H3-receptor antagonists (the electrically evoked contraction of the guinea-pig jejunum). It appeared that by comparison of homologous pairs the thiazolo derivatives have slightly higher activity than their oxazolo analogues. The most potent compound of these series is the 1-(2-thiazolo[4,5-c]pyridine)-4-n-propylpiperazine (3c) with pA2 = 7.25 (its oxazole analogue (4g) showed pA2 = 6.9). The structure-activity relationships for compounds with various positions of the nitrogen in the benzene ring for the thiazoles compared with oxazoles are discussed.
HETEROCYCLIC DERIVATIVES
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Page/Page column 16, (2011/02/25)
The present invention relates to heterocyclic derivatives, and more particularly, to novel heterocyclic derivatives useful for the preparation of medicaments for treating diseases related to uric acid.
