17084-13-8

Basic information

• Product Name: Potassium hexafluorophosphate
• Synonyms: hexafluoro-phosphate(1-potassium;Phosphate(1-),hexafluoro-,potassium;POTASSIUM HEXAFLUOROPHOSPHATE;POTASSIUM HEXAFLUOROPHOSPHATE (V);POTASSIUM HEXFLUOROPHOSPHATE;POTASSIUM HEXAFLUOROPHOSPHATE, 99.999%;Potassium fluorophosphate;Potassium hexafluorophosphate, extra pure, 99%
• CAS NO: 17084-13-8
• Molecular Formula: F₆P*K
• Molecular Weight: 184.06
• EINECS: 241-143-0
• Product Categories: Inorganic Salts;Potassium Salts;PotassiumMetal and Ceramic Science;Salts;Synthetic Reagents;Potassium;metal fluorophosphate complex;Preservative
• Mol File: 17084-13-8.mol

Chemical Properties

• Melting Point: 575 °C(lit.)
• Boiling Point: 100.9°C at 760 mmHg
• Flash Point: 14.8°C
• Appearance: White/Powder
• Density: 2.75 g/mL at 25 °C(lit.)
• Vapor Pressure: 41.5mmHg at 25°C
• Refractive Index: 1.366
• Storage Temp.: Refrigerator
• Solubility: Methanol (Slightly), Water (Soluble)
• Water Solubility: 93 g/L (25 ºC)
• Sensitive: Hygroscopic
• Stability: Stable. Incompatible with strong acids. Thermal decomposition may generate HF, phosphorus oxides and phosphine.
• CAS DataBase Reference: Potassium hexafluorophosphate(CAS DataBase Reference)
• NIST Chemistry Reference: Potassium hexafluorophosphate(17084-13-8)
• EPA Substance Registry System: Potassium hexafluorophosphate(17084-13-8)

Safety Data

• Hazard Codes: C,Xi
• Statements: 34-20/21/22
• Safety Statements: 26-27-36/37/39-45
• RIDADR: UN 3260 8/PG 2
• WGK Germany: 1
• TSCA: T
• HazardClass: 8
• PackingGroup: III
• Hazardous Substances Data: 17084-13-8(Hazardous Substances Data)

Usage

Uses

Used in Synthesis:
Potassium hexafluorophosphate is used as a reagent in the synthesis of various compounds. Its ability to act as a catalyst or a precursor in chemical reactions makes it a valuable component in the production of different substances.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, potassium hexafluorophosphate is used in the preparation of Moxifloxacin derivatives. Moxifloxacin is a fluoroquinolone antibiotic that is effective against a broad range of bacterial infections. The use of potassium hexafluorophosphate in the synthesis of its derivatives helps improve the drug's efficacy and target specific infections more effectively.
Used in Chemical Reactions:
Potassium hexafluorophosphate is also employed in various chemical reactions due to its unique properties. It can act as a catalyst, promoting the formation of desired products, or as a reactant, participating directly in the reaction to form new compounds. Its versatility in chemical processes makes it an essential component in the synthesis of various chemicals and materials.

Hazard

Toxic by ingestion.

Purification Methods

Crystallise it from alkaline aqueous solution, using polyethylene vessels, or from 95% EtOH, and dry it in a vacuum desiccator over KOH. [Kloditz Z Anorg Allgem Chem 284 144 1956, Kwasnik in Handbook of Preparative Inorganic Chemistry (Ed. Brauer) Academic Press Vol I p 196 1963.]

InChI:InChI:1S/F6P.K/c1-7(2,3,4,5)6;/q-1;+1

Upstream product

• 584-08-7 potassium carbonate 
• 1279123-63-5 potassium hydrogenfluoride 
• 7664-39-3 hydrogen fluoride 
• 7789-23-3 potassium fluoride 
• 7647-19-0 phosphorus pentafluoride 
• 10026-13-8 phosphorus pentachloride 
• 86119-84-8 phosphoric acid 
• 7787-71-5 bromine trifluoride 
• 10025-87-3 trichlorophosphate 
• 7789-59-5 phosphorus(V) oxybromide 
• 7783-55-3 trifluorophosphane 
• 7647-19-0 phosphorus pentafluoride 
• 16919-35-0 {PCl₄}⁽¹⁺⁾*{PF₆}^(1-)={PCl₄}{PF₆} 
• 3982-91-0 trichlorothiophosphine 

Downstream Products

• 149833-45-4 3,5-diiodophenyldiazonium hexafluorophosphate 
• 168886-77-9 1-(3,5-difluorobenzyl)-2-(1:3-dioxolan-2-yl)-pyridinium hexafluorophosphate 
• 322764-15-8 4-carboxymethoxyphenyl-2',4',6'-trimethylphenyliodonium hexafluorophosphate 
• 474304-24-0 4-carboxymethoxyphenyl-2',5'-dimethylphenyliodonium hexafluorophosphate 
• 322764-23-8 4-carboxymethoxyphenyl-2',3',5',6'-tetramethylphenyliodonium hexafluorophosphate 
• 322730-85-8 4-isopropoxycarbonylmethoxyphenyl-2',4',6'-trimethylphenyliodonium hexafluorophosphate 
• 322730-96-1 4-cyclohexyloxycarbonylmethoxyphenyl-2',4',6'-trimethylphenyliodonium hexafluorophosphate 
• 322730-92-7 4-(1-ethoxycarbonylethoxy)phenyl-2',4',6'-trimethylphenyliodonium hexafluorophosphate 
• 7789-23-3 potassium fluoride 
• 7647-19-0 phosphorus pentafluoride 
• 7732-18-5 water 
• 33990-35-1 {Rh(PH(C₆H₅)2)4}⁽¹⁺⁾*PF₆^(1-)={Rh(PH(C₆H₅)2)4}PF₆ 
• 217796-07-1 (1,3-bis(diphenylphosphino)propane)(η(4)-cyclooctadiene)rhodium(I) hexafluorophosphate 
• 84433-11-4 C₅H₅(CO)((C₆H₅)3P)Fe(COCH₂CH₂NH)⁽¹⁺⁾*PF₆^(1-)=[C₅H₅(CO)((C₆H₅)3P)Fe(COCH₂CH₂NH)]PF₆ 

Relevant articles and documents

Palladium chemistry in anhydrous HF/AsF5 superacid medium

Pd metal dissolves in anhydrous HF (aHF) acidified with AsF5 in the presence of F2 at ≈298 K to give a blue-green solution from which green Pd(AsF6)2 can be isolated. The latter was also prepared by the interaction of PdF2 and AsF5 in aHF or by the reaction between PdO and F2 in aHF acidified with AsF 5. Powdered Pd(AsF6)2 slowly loses AsF 5 in a dynamic vacuum. It can therefore be isolated from solution at T 6)2 were prepared by solvothermal synthesis from a Pd/AsF5/F2/aHF mixture at 393 K. Pd(AsF6)2 is triclinic with a = 500.9(5), b = 538.3(5), c = 864.9(9) pm, α = 74.46(3), β = 89.97(4), γ = 62.47(2)° V = 0.1972(3) nm3, and Z = 1, space group P1 (No. 2). The six-coordinate Pd atoms (coordinated with fluorine) are well separated by isolated AsF6 units. In the 2-175 K temperature range Pd(AsF 6)2 follows the Curie-Weiss law with μeff = 3.53 B.M., Tn = 8 K and θp = -13 K. Because of cation-anion interactions, the AsF6- anions deviate from ideal Oh symmetry. The reduced symmetry can be seen in vibrational spectra, where splitting of the anion vibrational modes can be observed. The oxidation of Pd metal or PdO with F2 in neutral aHF yielded Pd 2F6. No reaction was observed between Pd, PdO or Pd 2F6 and AsF5 in aHF. All attempts to prepare PdFAsF6 were unsuccessful. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004.

Synthesis of small tetranuclear Cu(I) metallacycles based on bridging pseudohalogenide ions

Three new 'short' metallacycles are selectively obtained from the reaction of a bimetallic CuI 'U-shape' molecular clip with, respectively, the cyano CN-, tricyanomethanide C(CN)3-, and azido N3- pseudohalogenide ions. These supramolecular assemblies have been characterized by spectroscopic methods, single-crystal X-ray diffraction, and elemental analysis. The single-crystal X-ray structures of these complexes reveal no short contact interaction between the pseudohalogenide ions within these self-assembled structures despite the short CuI·CuI distances within the molecular clips. The formation of these discrete metallacycles is rationalized by analyzing the structural features of the CuI 'U-shape' molecular clip.

Studies of how redox chemistry influences the synthesis of transition metal phosphametallocenes: A convenient synthesis of 2,5-diester-substituted phosphametallocenes and 2,2′,5,5′-tetraester-substituted-1,1′- diphosphaferrocenes

Convenient syntheses of 2,5-diester-substituted phosphametallocenes and 2,2′,5,5′-tetraester-substituted-1,1′-diphosphaferrocenes are described. Studies of the reactivity of alkali metal 3,4-dimethylphospholide, 2-ester-3,4-dimethyl phospholide and 2,5-diester-3,4-dimethylphospholide anions towards iron(ii) centres (as [Fe(AlCl4)2] or [Fe(MeCN)6(BF4)2]) indicate that the corresponding 1,1′-diphosphaferrocenes are obtained without any complications resulting from redox chemistry at the iron centre.

New Route to Battery Grade NaPF6 for Na-Ion Batteries: Expanding the Accessible Concentration

Sodium-ion batteries represent a promising alternative to lithium-ion systems. However, the rapid growth of sodium-ion battery technology requires a sustainable and scalable synthetic route to high-grade sodium hexafluorophosphate. This work demonstrates a new multi-gram scale synthesis of NaPF6 in which the reaction of ammonium hexafluorophosphate with sodium metal in THF solvent generates the electrolyte salt with the absence of the impurities that are common in commercial material. The high purity of the electrolyte (absence of insoluble NaF) allows for concentrations up to 3 M to be obtained accurately in binary carbonate battery solvent. Electrochemical characterization shows that the degradation dynamics of sodium metal-electrolyte interface are different for more concentrated (>2 M) electrolytes, suggesting that the higher concentration regime (above the conventional 1 M concentration) may be beneficial to battery performance.

Examining Trichloroisocyanuric Acid and Oxalyl Chloride in Complementary Approaches to Fluorination of Group 15 Heteroatoms

A mild, oxidative fluorination approach to a variety of fluorinated phosphorus compounds using trichloroisocyanuric acid (TCICA) and KF was developed as a complement to a recent study on deoxygenative fluorination using oxalyl chloride. Herein, the syntheses of several fluorinated organophosphorus compounds are reported, and both TCICA/KF and oxalyl chloride/KF conditions are compared and contrasted throughout. Initial investigations of the method on other group 15 heteroatoms (i. e., As, Sb, and Bi) are also reported, with varied success. This work notably extends the known TCICA/KF reactivity series to another group of elements beyond previously studied chalcogens (S, Se, and Te) and halogens (iodine) and expands the utility of the previously reported oxalyl chloride/KF method.

PRODUCTION OF A HEXAFLUOROPHOSPHATE SALT AND OF PHOSPHOROUS PENTAFLUORIDE

A process for producing a hexafluorophosphate salt comprises neutralizing hexafluorophosphoric acid with an organic Lewis base, to obtain an organic hexafluorophosphate salt. The organic hexafluorophosphate salt is reacted with an alkali hydroxide selected from an alkali metal hydroxide (other than LiOH) and an alkaline earth metal hydroxide, in a non-aqueous suspension medium, to obtain an alkali hexafluorophosphate salt as a precipitate. A liquid phase comprising the non-aqueous suspension medium, any unreacted organic Lewis base and any water that has formed during the reaction to form the precipitate, is removed. Thereby, the alkali hexafluorophosphate salt is recovered.

ARENE RUTHENIUM (II) DERIVATIVES CONTAINING IMINOPHOSPHORANE LIGANDS AND THEIR USE IN CANCER THERAPY

A method for providing a therapeutic benefit for a subject having a cancer is provided. A compound with an arene ruthenium (II) compound with an iminophosphorane ligand is administered to the subject.

COMPOUNDS CONTAINING HYDRIDO-TRICYANO-BORATE ANIONS

The present invention relates to compounds containing hydrido-tricya-borate anions, their preparation and their use, in particular as part of electrolyte formulations for electrochemical or optoelectronic devices.

Syntheses, crystal structures and magnetic properties of three novel cobalt(ii) complexes containing imidazole derivative groups

Three Co(ii) complexes with the formulas: {[Co2(Bib) 3Cl2]Cl(CH3COO)}·CH 3OH·H2O (1), [Co2(Bib) 3Cl2]Cl2·(CH3OH) 2·H2

The Kinetics and Mechanism of Hexafluorophosphate Ion Hydrolysis in the Presence of Li(1+) Ions

The kinetics of alkaline hydrolysis of the hexafluorophosphate ion in the presence of Li(1+) ions is studied in the temperature range 423-483 K.The observed rate constants, catalysis constants, and the activation pa rameters for the hydrolysis process are calculated. It is established that, under the experimental conditions, the energy requirements for the disintegration of the hydrate shells of PF6(1-) and Li(1+) are close to the effect of the weakening of the P-F bond under the influence of Li(1+)ions.