1745-77-3

Basic information

• Product Name: 2-BENZYLQUINOLINE
• Synonyms: 2-BENZYLQUINOLINE
• CAS NO: 1745-77-3
• Molecular Formula: C₁₆H₁₃N
• Molecular Weight: 219.28
• Mol File: 1745-77-3.mol
• Article Data: 25

Chemical Properties

• Boiling Point: 352.5°Cat760mmHg
• Flash Point: 151.3°C
• Appearance: /
• Density: 1.117g/cm³
• Vapor Pressure: 7.79E-05mmHg at 25°C
• Refractive Index: 1.649
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• CAS DataBase Reference: 2-BENZYLQUINOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BENZYLQUINOLINE(1745-77-3)
• EPA Substance Registry System: 2-BENZYLQUINOLINE(1745-77-3)

Safety Data

• Hazardous Substances Data: 1745-77-3(Hazardous Substances Data)

Usage

General Description

2-BENZYLQUINOLINE is a chemical compound that belongs to the quinoline family. It is a colorless to pale yellow oil with a melting point of -19 °C. 2-BENZYLQUINOLINE has various industrial applications, serving as a building block for the synthesis of pharmaceuticals, pesticides, and dyes. 2-BENZYLQUINOLINE is also utilized in research and development for its potential therapeutic properties, including its activity as an anti-tumor agent and its ability to inhibit the growth of harmful microorganisms. Due to its versatile properties, 2-BENZYLQUINOLINE is a valuable chemical in the fields of chemistry, medicine, and agriculture.

InChI:InChI=1/C16H13N/c1-2-6-13(7-3-1)12-15-11-10-14-8-4-5-9-16(14)17-15/h1-11H,12H2

Upstream product

• 91-22-5 quinoline 
• 6921-34-2 benzylmagnesium chloride 
• 101273-59-0 2-benzyl-quinolin-4-ol 
• 7664-41-7 ammonia 
• 108-90-7 chlorobenzene 
• 612-62-4 2-Chloroquinoline 
• 53317-09-2 9-benzyl-9-borabicyclo[3.3.1]nonane 
• 122-78-1 phenylacetaldehyde 
• 14277-00-0 N-phenylacetamidine 
• 119373-39-6 1-benzylcyclopropan-1-ol 
• 62-53-3 aniline 
• 1613-37-2 Quinoline N-oxide 
• 770-09-2 benzyltrimethylsilane 
• 2005-43-8 2-bromoquinoline 

Downstream Products

• 95113-34-1 N-(2-quinolyl)-2-benzylidene-1,2-dihydroquinoline 
• 3678-74-8 2-(Diphenylmethyl)quinoline 
• 50610-82-7 1,2,3,4-tetrahydro-2-(phenylmethyl)quinoline 
• 1139921-59-7 (R)-2-benzyl-1,2,3,4-tetrahydroquinoline 
• 16576-25-3 2-benzoylquinoline 
• 23974-78-9 2-benzylquinoline 1-oxide 
• 102181-27-1 (3-[2]quinolyl-3-phenyl-propyl)-dimethyl-amine 

Relevant articles and documents

Polar Effects in Free-Radical Reactions. Selectivity and Reversibility in the Homolytic Benzylation of Protonated Heteroaromatic Bases

The homolytic benzylation of protonated 4-cyanopyridine, quinoline, 2-methyl- and 4-methylquinoline, isoquinoline, and quinoxaline is investigated.The great influence of the polar effect and of the reversibility of the addition of the benzyl radical on the reaction selectivity is discussed.It is put forward the hypothesis that the HSAB principle can be extended to free-radical reactions when the polar effect is the dominant factor.

A Metal- and Azide-free Oxidative Coupling Reaction for the Synthesis of [1,2,3]Triazolo[1,5-a]quinolines and their Application to Construct C?C and C-P Bonds, 2-Cyclopropylquinolines and Imidazo[1,5-a]quinolines

An iodine-promoted one-pot cascade oxidative annulation reaction has been developed for the synthesis of [1,2,3]triazolo[1,5-a]quinolines from methyl azaarenes and N-tosylhydrazines. The reaction has a broad substrate scope and can be easily scaled up to gram-scale. 1,2,3-Triazoles are an important skeletal structure for the construction of C?C and C?P bonds, 2-cyclopropylquinolines and imidazo[1,5-a]quinolines, for which different synthetic applications were explored. (Figure presented.).

Catalytic Selective Metal-Free Cross-Coupling of Heteroaromatic N-Oxides with Organosilanes

A metal-free, regioselective C-H functionalization of heteroaromatic N-oxides has been developed. The method enables the synthesis of various benzylated and alkynylated N-heterocycles in a transition-metal-free manner employing organosilanes as coupling partners. The unanticipated reactivity has been exploited for the synthesis of a number of symmetrical disubstituted acetylenes from ethynyltrimethylsilane via carbon-silicon bond metathesis.