17789-14-9

Basic information

• Product Name: 2-(3-BROMOPHENYL)-1,3-DIOXOLANE
• Synonyms: 1,3-Dioxolane, 2-(m-bromophenyl)-;2-(3-Bromophenyl)dioxolane;m-Bromobenzaldehyde ethylene acetal;3-BROMOBENZALDEHYDE ETHYLENE ACETAL;2-(3-BROMOPHENYL)-1,3-DIOXOLANE;1-BROMO-3-(1,3-DIOXOLAN-2-YL)BENZENE;RARECHEM AL BP 0052;2-(m-bromophenyl)-1,3-dioxolane
• CAS NO: 17789-14-9
• Molecular Formula: C₉H₉BrO₂
• Molecular Weight: 229.07
• EINECS: 241-766-8
• Product Categories: Benzaldehyde;Adehydes, Acetals & Ketones;Bromine Compounds;Dioxanes & Dioxolanes;Dioxolanes;Acetals/Ketals/Ortho Esters;Organic Building Blocks;Oxygen Compounds
• Mol File: 17789-14-9.mol
• Article Data: 24

Chemical Properties

• Boiling Point: 132-133 °C8 mm Hg(lit.)
• Flash Point: >230 °F
• Appearance: /
• Density: 1.514 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.001mmHg at 25°C
• Refractive Index: n20/D 1.563(lit.)
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• BRN: 1344030
• CAS DataBase Reference: 2-(3-BROMOPHENYL)-1,3-DIOXOLANE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-BROMOPHENYL)-1,3-DIOXOLANE(17789-14-9)
• EPA Substance Registry System: 2-(3-BROMOPHENYL)-1,3-DIOXOLANE(17789-14-9)

Safety Data

• Safety Statements: 24/25
• WGK Germany: 3
• Hazardous Substances Data: 17789-14-9(Hazardous Substances Data)

Usage

Uses

2-(3-Bromophenyl)-1,3-dioxolane was used in the synthesis of acetal by arylation of 1-benzylpiperidin-4-amine.

InChI:InChI=1/C10H11BrO2/c11-9-4-1-3-8(7-9)10-12-5-2-6-13-10/h1,3-4,7,10H,2,5-6H2

Upstream product

• 3132-99-8 m-bromobenzoic aldehyde 
• 7381-30-8 2,2,7,7-tetramethyl-3,6-dioxa-2,7-disilaoctane 
• 646-06-0 1,3-DIOXOLANE 
• 89598-96-9 (3-bromophenyl)boronic acid 
• 107-21-1 ethylene glycol 

Downstream Products

• 151055-85-5 2-<3-(1H-imidazol-1-yl)phenyl>-1,3-dioxolane 
• 936-51-6 2-phenyl-1,3-dioxolane 
• 153329-04-5 3-(1,3-dioxolan-2-yl)-benzonitrile 
• 85366-46-7 (3-(1,3-dioxolan-2-yl)phenyl)(phenyl)methanone 
• 177414-57-2 (3-[1,3]dioxolan-2-ylphenyl)phenylmethanol 
• 3132-99-8 m-bromobenzoic aldehyde 
• 201851-07-2 2-(3-(methylthio)phenyl)-1,3-dioxolane 
• 201851-04-9 2-(3-cyclopentylphenyl)-1,3-dioxolane 
• 201851-02-7 2-(3-cyclopropylphenyl)-1,3-dioxolane 
• 203510-50-3 3-[4-(3-[1,3]Dioxolan-2-yl-phenoxy)-phenyl]-propionic acid methyl ester 
• 237069-40-8 6-methoxy-2-[3-(1,3-dioxolan-2-yl)phenyl]naphthalene 
• 237069-30-6 6-methoxy-2-[3-(1,3-dioxolan-2-yl)phenyl]-3,4-dihydronaphthalene 
• 182805-28-3 1-(3-(3-(1,3-Dioxolan-2-yl)phenyl)prop-1-enyl)-1-(4-ethoxyphenyl)cyclopropane 

Relevant articles and documents

Visible-Light Mediated Oxidative Fragmentation of Ethers and Acetals by Means of Fe(III) Catalysis

A new method employing iron(III) acetylacetonate along with visible light is described to effect oxidative ring opening of cyclic ethers and acetals with unparalleled efficiency. The method allows for a photocatalytic radical chemistry approach to functionalize relatively inert cyclic ethers into useful synthetic intermediates. The methodology sheds further light on the use of underexplored iron complexes in visible-light photochemical contexts and illustrates that simple Fe(III) complexes can initiate redox processes from 4LMCT excited states.

MODULATORS OF HEMOGLOBIN FOR THE TREATMENT OF SICKLE CELL DISEASE

The present disclosure relates to compounds of the general formula (I) and pharmaceutical compositions containing them. The compounds are suitable as modulators of hemoglobin and thus useful in treating disorders mediated by hemoglobin such as sickle cell disease.

Ni-Catalyzed Site-Selective Dicarboxylation of 1,3-Dienes with CO2

A site-selective catalytic incorporation of multiple CO2 molecules into 1,3-dienes en route to adipic acids is described. This protocol is characterized by its mild conditions, excellent chemo- and regioselectivity and ease of execution under CO2 (1 atm), including the use of bulk butadiene and/or isoprene feedstocks.