191043-26-2

Basic information

• Product Name: 2-Oxazolidinethione, 4-methyl-5-phenyl-, (4S,5R)-
• CAS NO: 191043-26-2
• Molecular Formula: C10H11NOS
• Molecular Weight: 193.269
• Mol File: 191043-26-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-Oxazolidinethione, 4-methyl-5-phenyl-, (4S,5R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Oxazolidinethione, 4-methyl-5-phenyl-, (4S,5R)-(191043-26-2)
• EPA Substance Registry System: 2-Oxazolidinethione, 4-methyl-5-phenyl-, (4S,5R)-(191043-26-2)

Safety Data

• Hazardous Substances Data: 191043-26-2(Hazardous Substances Data)

Upstream product

• 492-41-1 (1R,2S)-norephedrine 
• 2131-55-7 4-Chlorophenyl isothiocyanate 
• 4430-49-3 4,4′-sulfonylbis(isothiocyanatobenzene) 
• 542-85-8 Ethyl isothiocyanate 
• 75-15-0 carbon disulfide 

Downstream Products

• 104499-13-0 (R)-3,3,3-Trifluoro-2-methoxy-1-((4R,5S)-4-methyl-5-phenyl-2-thioxo-oxazolidin-3-yl)-2-phenyl-propan-1-one 
• 130272-30-9 (E)-(4S,5R)-4-methyl-3-(3'-phenyl-2'-propenoyl)-5-phenyl-2-oxazolidinone 
• 908848-31-7 4-methyl-5-phenyl-3-vinyl-oxazolidine-2-thione 
• 16251-45-9 (4S,5R)-4-methyl-5-phenyl-oxazolidin-2-one 
• 599199-35-6 (1R,3R,4S,7R,8R,11R)-8-(4-chlorophenyl)-4-methyl-3,11-diphenyl-2,9-dioxa-10-thia-5-azatricyclo[5.2.2.0^1,5]undecan-6-one 
• 899426-22-3 (4S,5R,2'R,3'R,1''R)-3-[3'-(4-chlorophenyl)-2'-(1''-methylsulfanyl-1''-phenylmethyl)-3'-trimethylsilanyloxypropionyl]-4-methyl-5-phenyloxazolidin-2-one 
• 899426-20-1 (4S,5R,2'R,3'R,1''R)-3-[3'-(4-chlorophenyl)-3'-hydroxy-2'-(1''-methylsulfanyl-1''-phenylmethyl)propionyl]-4-methyl-5-phenyloxazolidin-2-one 
• 899426-18-7 (4S,5R,2'R,3'R,1''R)-3-[3'-(4-chlorophenyl)-3'-hydroxy-2'-(1''-sulfanyl-1''-phenylmethyl)propionyl]-4-methyl-5-phenyloxazolidin-2-one 
• 599164-43-9 (4S,5R)-4-methyl-5-phenyl-3-[(E)-phenylprop-2-enoyl]-1,3-oxazolidine-2-thione 
• 599164-42-8 (E)-1-((4S,5R)-4-Methyl-5-phenyl-2-thioxo-oxazolidin-3-yl)-but-2-en-1-one 

Relevant articles and documents

A new method for the synthesis of 5- and 6-membered 2-thioxo-1,3-O,N-heterocycles

Various 1,3-oxazolidine-2-thiones and tetrahydro-1,3-oxazine-2-thiones are prepared by reacting hydrogen peroxide with a mixture of amino alcohols, carbon disulfide and base in a water-miscible organic solvent. The yields of the heterocyclic products are

Semisynthsis of novel sulfonamides, thioureas and biphenylsulfones as a new class of anticancer agents by using L-norephedrine as strategic starting material

In continuation of our work on synthesis of novel anticancer agents, a new series of sulfonamides carrying a biologically active thiourea 3, 4, biphenylsulfones bearing thiourea 8-10 and oxazole thione 11 were designed and synthesized using L-norephedrine

(S)-4-Isopropyl-5,5-dimethyl-1,3-oxazolidinethione as chiral auxiliary for the intramolecular sulfur transfer in α,β-unsaturated N-acylimides, promoted by NbCl5

The 1,3-oxazolidinethione 4 has been synthesized from (S)-valine and used in the intramolecular sulfur transfer in its N-enoyl derivatives in the presence of NbCl5 as catalyst, which, moreover, works as an indicator of the course of the reactio