1969-74-0Relevant articles and documents
A one-step synthesis of 2-(2-pyridyl)-3H-indol-3-one N-oxide: Is it an efficient spin trap for hydroxyl radical?
Rosen, Gerald M.,Tsai, Pei,Barth, Eugene D.,Dorey, Gilbert,Casara, Patrick,Spedding, Michael,Halpern, Howard J.
, p. 4460 - 4463 (2000)
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Intermolecular Interception of α-Oxo Gold Carbenes of Nitroalkyne Cycloisomerization with 1,2-Benzo[ d]isoxazole: Synthesis of Functionalized Quinazoline 1-Oxides
Dhote, Pawan S.,Pund, Kishor A.,Ramana, Chepuri V.
, p. 10874 - 10882 (2021)
The known nitrogen-transfer reagent 1,2-benzo[d]isoxazole has been used to trap the postulated α-oxo gold carbene intermediate involved in the [Au]-catalyzed internal redox process of 2-alkynylnitrobenzenes. This process led us to develop a general conver
One-Pot Synthesis of Fused Indolin-3-Ones via a [3+3] Cycloaddition Reaction
Huang, Lang,Yao, Zhenyu,Huang, Guanghua,Ao, Yaqi,Zhu, Bin,Li, Sanshu,Cui, Xiuling
supporting information, p. 5092 - 5098 (2021/09/25)
A formal [3+3] cycloaddition reaction of azaoxyallyl cations and isatogens generated in situ from α-halo hydroxamates and o-nitroalkynes, respectively, was developed. The cycloisomerization of the o-nitroalkynes, followed by base-mediated elimination of h
C-H alkenylation/cyclization and sulfamidation of 2-phenylisatogens using: N -oxide as a directing group
Guo, Lingmei,Tang, Baolan,Nie, Ruifang,Liu, Yanzhao,Lv, Shan,Wang, Huijing,Guo, Li,Hai, Li,Wu, Yong
supporting information, p. 10623 - 10626 (2019/09/06)
The first example of transition-metal-catalyzed C-H activations of 2-phenylisatogens with alkynes and sulfonyl azides has been developed using N-oxide as the directing group. Ru(ii)-Catalyzed C-H alkenylation/cyclization and Ir(iii)-catalyzed direct C-H sulfamidation proceeded with good yields and excellent functional group tolerance. Importantly, these two transformations provided straightforward routes for the synthesis of indol-3-one derivatives and sulfamidated 2-phenylisatogens respectively, which might be of considerable bioactivities.