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19994-56-0

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19994-56-0 Usage

Description

2-Amino-3-cyano-5-methylpyrazine 1-oxide is a pyrazine derivative with the chemical formula C6H5N3O and a molecular weight of 147.12 g/mol. It is a yellow to brown solid that is primarily used as a synthetic intermediate in the production of pharmaceuticals and agrochemicals. 2-AMINO-3-CYANO-5-METHYLPYRAZINE 1-OXIDE also serves as a flavoring agent in the food industry and has been studied for its potential biological activities, such as antifungal and cytotoxic properties.

Uses

Used in Pharmaceutical Industry:
2-Amino-3-cyano-5-methylpyrazine 1-oxide is used as a synthetic intermediate for the development of various pharmaceuticals. Its unique chemical structure allows it to be a key component in the synthesis of drugs with specific therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical industry, 2-amino-3-cyano-5-methylpyrazine 1-oxide is utilized as a synthetic intermediate for the production of agrochemicals. Its incorporation into these products can contribute to the effectiveness of pesticides, herbicides, and other agricultural chemicals.
Used as a Flavoring Agent in the Food Industry:
2-Amino-3-cyano-5-methylpyrazine 1-oxide is employed as a flavoring agent in the food industry, where it imparts specific taste profiles to various food products. Its use in this capacity highlights its versatility and the broad range of applications it possesses.
Used in Biological Research:
2-Amino-3-cyano-5-methylpyrazine 1-oxide has been studied for its potential biological activities, such as antifungal and cytotoxic properties. This research is crucial for understanding the compound's potential applications in medicine and other fields, as well as for developing new treatments and therapies.

Check Digit Verification of cas no

The CAS Registry Mumber 19994-56-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,9,9 and 4 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 19994-56:
(7*1)+(6*9)+(5*9)+(4*9)+(3*4)+(2*5)+(1*6)=170
170 % 10 = 0
So 19994-56-0 is a valid CAS Registry Number.

19994-56-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-hydroxy-3-imino-6-methylpyrazine-2-carbonitrile

1.2 Other means of identification

Product number -
Other names AR2267

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:19994-56-0 SDS

19994-56-0Relevant articles and documents

Discovery of pyrazol-3-ylamino pyrazines as novel JAK2 inhibitors

Ioannidis, Stephanos,Lamb, Michelle L.,Davies, Audrey M.,Almeida, Lynsie,Su, Mei,Bebernitz, Geraldine,Ye, Minwei,Bell, Kirsten,Alimzhanov, Marat,Zinda, Michael

scheme or table, p. 6524 - 6528 (2010/05/18)

The design, synthesis and biological evaluation of a series of pyrazol-3-ylamino pyrazines as potent and selective JAK2 kinase inhibitors is reported, along with the pharmacokinetic and pharmacodynamic properties of lead compounds.

HETEROARYL UREA DERIVATIVES USEFUL FOR INHIBITING CHKl

-

Page/Page column 65, (2008/06/13)

Substituted urea compounds useful in the treatment of diseases and conditions related to DNA damage or lesions in DNA replication are disclosed. Methods of making the compounds, and their use as therapeutic agents, for example, in treating cancer and other diseases characterized by defects in DNA replication, chromosome segregation, or cell division, also are disclosed.

Pteridines. 47. Preparation and Chemistry of 2-Amino-6-carbalkoxy-3-cyano-5-substituted Pyrazine 1-Oxides: Synthesis of Pterin-6-carboxaldehyde

Taylor, Edward C.,Dumas, Donald J.

, p. 2485 - 2489 (2007/10/02)

A new procedure for the synthesis of 2-amino-3-cyano-5-substituted pyrazines 9, useful intermediates for the synthesis of pteridines, is described.Oximation of β-keto esters 2 followed by reaction with aminomalononitrile provides 2-amino-6-carbalkoxy-3-cyano-5-substituted pyrazine 1-oxides 5.Protection of the amino group as its ((dimethylamino)methylene)amino derivative 9 followed by SN2 decarbalkoxylation provides pyrazines 10 which on removal of the protecting group and deoxygenation give pyrazines 8.This method is designed to be of use in cases where the β-keto ester cannot be converted directly to the corresponding α-keto aldoxime 3.The procedure is applied to the synthesis of 2-amino-3-cyano-5-(dimethoxymethyl)pyrazine (8a), an intermediate in the synthesis of pterin-6-carboxaldehyde (1).

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