20734-67-2Relevant articles and documents
First synthesis of BU-4664L
Takahashi, Yusuke,Hirokawa, Takafumi,Watanabe, Mai,Fujita, Satomi,Ogura, Yusuke,Enomoto, Masaru,Kuwahara, Shigefumi
, p. 5670 - 5672 (2015)
The first synthesis of BU-4664L, an actinomycte-produced N-farnesylated dibenzodiazepinone with important biological activities, has been achieved in 18% overall yield from a known benzoic acid derivative by a nine-step sequence that involves an intramolecular Buchwald-Hartwig coupling of a sterically demanding bromo amine intermediate to install the unique tricyclic ring system.
Heck arylation of styrenes promoted by an air-stable phosphinito complex with palladium(II); Synthesis of resveratrol
Morales-Serna, Jose Antonio,Zuniga-Martinez, Armando,Salmon, Manuel,Gavino, Ruben,Cardenas, Jorge
experimental part, p. 446 - 452 (2012/03/11)
An air-stable phosphinito complex of palladium(II) was found to be an efficient catalyst in the Heck reaction of a variety of aryl halides and styrenes. Resveratrol was concisely synthesized in 63% overall yield; the reactions were performed under conventional and microwave heating. Georg Thieme Verlag Stuttgart New York.
Synthesis of resveratrol using a direct decarbonylative Heck approach from resorcylic acid
Andrus, Merritt B.,Liu, Jing,Meredith, Erik L.,Nartey, Edward
, p. 4819 - 4822 (2007/10/03)
The phytoalexin resveratrol has been made using a decarbonylative Heck reaction. The acid chloride derived from 3,5-dihydroxybenzoic acid was coupled with 4-acetoxystyrene in the presence of palladium acetate and N,N-bis-(2,6-diisopropylphenyl)dihydroimidazolium chloride to give the substituted stilbene in 73% yield as the key step.