208581-60-6Relevant articles and documents
Investigation of Lysine-Functionalized Dendrimers as Dichlorvos Detoxification Agents
Durán-Lara, Esteban F.,Marple, Jennifer L.,Giesen, Joseph A.,Fang, Yunlan,Jordan, Jacobs H.,Godbey, W Terrence,Marican, Adolfo,Santos, Leonardo S.,Grayson, Scott M.
, p. 3434 - 3444 (2015)
Lysine-containing polymers have seen broad application due to their amines inherent ability to bind to a range of biologically relevant molecules. The synthesis of multiple generations of polyester dendrimers bearing lysine groups on their periphery is de
Design, synthesis, and biological evaluation of a robust, biodegradable dendrimer
Van Der Poll, Derek G.,Kieler-Ferguson, Heidi M.,Floyd, William C.,Guillaudeu, Steven J.,Jerger, Katherine,Szoka, Francis C.,Fréchet, Jean M.
scheme or table, p. 764 - 773 (2011/02/25)
PEGylated dendrimers are attractive for biological applications due to their tunable pharmacokinetics and ability to carry multiple copies of bioactive molecules. The rapid and efficient synthesis of a robust and biodegradable PEGylated dendrimer based on
TUNED SYNTHETIC DENDRIMER CALIBRANTS FOR MASS SPECTROMETRY
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Page/Page column 24; 25; Sheet 5/19, (2010/08/18)
Provided are monodisperse synthetic dendrimer calibrants for mass spectrometry. The calibrants are distinguished by their relative ease and rapidity of synthesis, comparatively low cost, long shelf life, high purity, and amenability to batch synthesis as mixtures. The latter characteristic enables parallel preparation of higher molecular weight compounds displaying useful distributions of discrete molecular weights, thereby providing multi-point mass spectrometry calibration standards. Methods of making and using said calibrants are also provided.
Benzylidene protected bis-MPA: A convenient dendrimer building block
Annby, Ulf,Malmberg, Mats,Pettersson, Bo,Rehnberg, Nicola
, p. 3217 - 3220 (2007/10/03)
Benzylidene protected bis-MPA, 2,2-bis(hydroxymethyl)propanoic acid, was synthesised and evaluated as building block in the construction of dendrimers. It was found that the anhydride of benzylidene protected bis-MPA reacts with neopentylic alcohols to give high yields of acylated products. Purification is facilitated by the crystalline nature of most ester products. Deprotection by hydrogenolysis gives polyol dendrimers in good yields.