23092-75-3

Basic information

• Product Name: 1-(6-Chloropyridin-3-yl)ethanol
• Synonyms: 1-(6-Chloropyridin-3-yl)ethanol;6-Chloro-a-Methyl-3-pyridineMethanol
• CAS NO: 23092-75-3
• Molecular Formula: C₇H₈ClNO
• Molecular Weight: 157.59752
• Mol File: 23092-75-3.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 120-121 °C(Press: 0.15 Torr)
• Appearance: /
• Density: 1.253±0.06 g/cm3(Predicted)
• PKA: 13.39±0.20(Predicted)
• CAS DataBase Reference: 1-(6-Chloropyridin-3-yl)ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(6-Chloropyridin-3-yl)ethanol(23092-75-3)
• EPA Substance Registry System: 1-(6-Chloropyridin-3-yl)ethanol(23092-75-3)

Safety Data

• Hazardous Substances Data: 23092-75-3(Hazardous Substances Data)

Usage

Appearance

White to off-white solid

Solubility

Soluble in organic solvents

Synonyms

6-Chloro-3-pyridylethanol

Usage

Building block in the synthesis of pharmaceuticals and agrochemicals

Versatility

Can undergo various chemical reactions to produce a wide range of compounds

Application

Commonly used in research and development laboratories as a precursor in the synthesis of biologically active molecules

Safety

Handle with caution due to potential health risks if mishandled or used improperly

Upstream product

• 139042-59-4 1-(6-bromopyridin-3-yl)ethanone 
• 23100-12-1 6-chloronicotinylaldehyde 
• 676-58-4 methylmagnesium chloride 
• 624-28-2 2,5-dibromopyridine 
• 58757-38-3 6-Chloronicotinoyl chloride 
• 55676-22-7 3-acetyl-6-chloropyridine 

Downstream Products

• 113841-58-0 1-(6-chloropyridin-3-yl)ethyl 4-methylbenzenesulfonate 

Relevant articles and documents

Synthesis of a neonicotinoide pesticide derivative via chemoenzymatic dynamic kinetic resolution

(Chemical Equation Presented) Chemoenzymatic dynamic kinetic resolution (DKR) via combined ruthenium and enzyme catalysis was used in the key step of a synthesis of a neonicotinoid pesticide derivative (S)-3. The DKR was carried out under mild conditions

TRIAZOLYL AMINOPYRIMIDINE COMPOUNDS

The present invention provides triazolyl aminopyrimidine compounds useful in the treatment of cancer.

Enantioselective Synthesis of Optically Active Pyridine Derivatives and C2-Symmetric 2,2'-Bipyridines

Optically active pyridine derivatives 2, 15, 18, 19, 21, 26, and 27 are obtained by enantioselective reduction of the corresponding ketones 5, 7, 11-13, 24, and 25 using the chiral borane reagent chlorodiisopinocampherylborane .Nickel(0)-mediated coupling of bromopyridines 2, 15, and 31 gives C2-symmetric 2,2'-bipyridines (R,R)-32, (R,R)-33, and (S,S)-38, respectively, which form metal complexex with Co(II), Pd(II), Cu(I), and Ag(I).Aryl-substituted pyridines 26, and 39-41 are synthesized by palladium(0)-catalized cross coupling of 2 and 15 with boronic acids 42-44.Key Words: 2,2-Bipyridines / Pyridines, optically active / Chiral ligands / Asymmetric Synthesis / Catalysis, enantioselective