2571-39-3

Basic information

• Product Name: 3,4-Dimethylbenzophenone
• Synonyms: 3,4-DIMETHYLBENZOPHENONE;Benzophenone, 3,4-dimethyl-;Methanone, (3,4-dimethylphenyl)phenyl-;(3,4-Dimethylphenyl)phenyl-methanone;(3,4-Dimethylphenyl)phenyl ketone;Phenyl 3,4-xylyl ketone;3,4-Dimethylbenzophe;3,4-Dimethylb
• CAS NO: 2571-39-3
• Molecular Formula: C₁₅H₁₄O
• Molecular Weight: 210.27
• EINECS: 219-916-9
• Product Categories: Aromatic Benzophenones & Derivatives (substituted);Benzophenone;Organic Photoinitiators;Polymerization Initiators
• Mol File: 2571-39-3.mol

Chemical Properties

• Melting Point: 45-47 °C(lit.)
• Boiling Point: 335°C
• Flash Point: >230 °F
• Appearance: /
• Density: 1.0232 (rough estimate)
• Refractive Index: 1.5361 (estimate)
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: soluble in Methanol
• BRN: 1952043
• CAS DataBase Reference: 3,4-Dimethylbenzophenone(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-Dimethylbenzophenone(2571-39-3)
• EPA Substance Registry System: 3,4-Dimethylbenzophenone(2571-39-3)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39-24/25-22-36
• WGK Germany: 3
• Hazardous Substances Data: 2571-39-3(Hazardous Substances Data)

Usage

Uses

Used in Polymer Production:
3,4-Dimethylbenzophenone is utilized as a photoinitiator for the synthesis of various polymers, including acrylic resins and adhesives. It is instrumental in initiating the polymerization process when exposed to ultraviolet light, which is crucial for the manufacturing of these materials.
Used in Cosmetics Industry:
In the cosmetics industry, 3,4-Dimethylbenzophenone serves as an additive in products like sunscreen to provide ultraviolet (UV) protection. Its inclusion helps to shield the skin from harmful UV rays, thereby reducing the risk of skin damage and other related conditions.

Upstream product

• 2159-42-4 2-(3,4-dimethylbenzoyl)benzoic acid 
• 95-47-6 o-xylene 
• 98-88-4 benzoyl chloride 
• 65-85-0 benzoic acid 
• 98-07-7 Benzotrichlorid 
• 618-32-6 Benzoyl bromide 
• 58753-23-4 4-benzoyl-1,2-dimethyl-1-cyclohexene 
• 93-58-3 benzoic acid methyl ester 
• 93-97-0 benzoic acid anhydride 
• 774-65-2 benzoic acid tert-butyl ester 
• 21900-23-2 3,4-dimethylbenzoyl chloride 
• 71-43-2 benzene 
• 14189-53-8 3,4-dimethylbenzhydrol 
• 100-52-7 benzaldehyde 

Downstream Products

• 14189-53-8 3,4-dimethylbenzhydrol 
• 13540-56-2 4-benzyl-1,2-dimethylbenzene 
• 93765-37-8 (3,4-Dimethyl-phenyl)-phenyl-pyrimidin-5-yl-methanol 
• 107369-26-6 3,4-bis(dibromomethyl)benzophenone 
• 99393-15-4 3,4-dimethyldiphenylitaconic acid 
• 99405-58-0 3,4-dimethyldiphenylitaconic acid 
• 54588-82-8 3,4-Dimethyl-thiobenzophenon 
• 4072-14-4 (4,5-dimethyl-2-hydroxyphenyl)(phenyl)methanone 
• 3885-88-9 4-benzoyl-phthalic acid 
• 38736-42-4 3.4-dimethyl-benzophenone-[(2.4-dinitro-phenyl)-seqtrans-hydrazone] 
• 5580-33-6 3,4-dimethylbenzamide 
• 55-21-0 benzamide 
• 107369-33-5 7-benzoylbenzobiphenylene 
• 34877-58-2 Methyl-<2-hydroxy-2-phenyl-2-(3,4-dimethylphenyl)>-sulfon 

Relevant articles and documents

Fe-S Catalyst Generated in Situ from Fe(III)- And S3?--Promoted Aerobic Oxidation of Terminal Alkenes

An iron-sulfur complex formed by the simple mixture of FeCl3 with S3?- generated in situ from K2S is developed and applied to selective aerobic oxidation of terminal alkenes. The reaction was carried out under an atmosphere of O2 (balloon) and could proceed on a gram scale, expanding the application of S3?- in organic synthesis. This study also encourages us to explore the application of an Fe-S catalyst in organic reactions.

Photo-induced oxidative cleavage of C-C double bonds for the synthesis of biaryl methanoneviaCeCl3catalysis

A Ce-catalyzed strategy is developed to produce biaryl methanonesviaphotooxidative cleavage of C-C double bonds at room temperature. This reaction is performed under air and demonstrates high activity as well as functional group tolerance. A synergistic Ce/ROH catalytic mechanism is also proposed based on the experimental observations. This protocol should be the first successful Ce-catalyzed photooxidation reaction of olefins with air as the oxidant, which would provide inspiration for the development of novel Ce-catalyzed photochemical synthesis processes.

Decatungstate-mediated solar photooxidative cleavage of CC bonds using air as an oxidant in water

With the increasing attention for green chemistry and sustainable development, there has been much interest in searching for greener methods and sources in organic synthesis. However, toxic additives or solvents are inevitably involved in most organic transformations. Herein, we first report the combination of direct utilization of solar energy, air as the oxidant and water as the solvent for the selective cleavage of CC double bonds in aryl olefins. Various α-methyl styrenes, diaryl alkenes as well as terminal styrenes are well tolerated in this green and sustainable strategy and furnished the desired carbonyl products in satisfactory yields. Like heterogeneous catalysis, this homogeneous catalytic system could also be reused and it retains good activity even after repeating three times. Mechanism investigations indicated that both O2- and 1O2 were involved in the reaction. Based on these results, two possible mechanisms, including the electron transfer pathway and the energy transfer pathway, were proposed.

A sodium trifluoromethanesulfinate-mediated photocatalytic strategy for aerobic oxidation of alcohols

A sodium trifluoromethanesulfinate-mediated photocatalytic strategy for the aerobic oxidation of alcohols has been developed for the first time, and the photoredox aerobic oxidation of secondary and primary alcohols provided the corresponding ketones and carboxylic acids, respectively, in high to excellent yields.

Preparation method of aromatic ketone

The invention discloses a preparation method of aromatic ketone. Under the effects of a palladium catalyst and a nitrogen-containing ligand, nitrile compounds and arylsulfonylhydrazide take desulfurization addition reaction in an organic solvent; after the reaction is completed, post treatment is performed to obtain aromatic ketone. The reaction is applicable to aromatic nitrile compounds, and isalso applicable to aliphatic nitrile compounds; the reaction realizes the wide substrate applicability and functional group tolerance; the potential application value is realized in the aspect of aryl-carbonyl building.

Method for preparing aromatic ketone in aqueous phase

The invention discloses a method for preparing aromatic ketone in an aqueous phase, comprising the following steps: enabling aryl formyl potassium formate and aryl potassium fluoborate to generate decarboxylation acylation reaction in water under the actions of a silver catalyst and an oxidizing agent, and performing treatment after reaction is ended to obtain the disclosed aromatic ketone. According to the preparation method, the silver catalyst replaces a noble metal catalyst, water is taken as a solvent, an aromatic ketone product is obtained with relatively high yield, the adopted catalystis low in cost and easy to obtain, reaction conditions are mild, and meanwhile, the product is good in university, and therefore, the method has good application potential.

Pd(II)-Catalyzed Denitrogenative and Desulfinative Addition of Arylsulfonyl Hydrazides with Nitriles

A Pd(II)-catalyzed denitrogenative and desulfinative addition of arylsulfonyl hydrazides with nitriles has been successfully achieved under mild conditions. This transformation is a new method for the addition reaction to nitriles with arylsulfonyl hydrazides as arylating agent, thus providing an alternative synthesis of aryl ketones. The reported addition reaction is tolerant to many common functional groups, and works well in the presence of electron-donating and electron-withdrawing substituents. Notably, the reported denitrogenative and desulfinative addition was also appropriate for alkyl nitriles, making this newly developed transformation attractive.

A kind of alkali to promote self-oxidation of diaryl alkane preparation diarylketones method (by machine translation)

The invention discloses a kind of alkali to promote self-oxidation of diaryl alkane preparation diarylketones method. The method is that the diaryl paraffins compound is dissolved in an organic solvent in the drying of, the addition of a base, in the 25 - 80o C reaction under air or oxygen atmosphere for 0.5 - 5 hours, to obtain diarylketones; said two aryl paraffins compound and alkali molar ratio of 1:1 - 1:3. The method overcomes the need in the prior art strong acid or expensive metal reagent or a strong oxidizing agent and the like, has the following advantages: 1) to oxygen as the oxidizing agent, avoids the use of strong or expensive chemical oxidizing agent; 2) transition metal-free catalyst, avoids the heavy metal ion in the product; 3) the process is simple, low cost, wide range of the substrate, friendly to the environment. The synthesis method disclosed in this invention in the preparation of diarylketones industrialization of the play an important role in the production. (by machine translation)

P -Selective (sp2)-C-H functionalization for an acylation/alkylation reaction using organic photoredox catalysis

p-Selective (sp2)-C-H functionalization of electron rich arenes has been achieved for acylation and alkylation reactions, respectively, with acyl/alkylselenides by organic photoredox catalysis involving an interesting mechanistic pathway.

T-BuONa-Mediated Transition-Metal-Free Autoxidation of Diarylmethanes to Ketones

Autoxidative sp3 C-H transformation of diarylmethanes has been demonstrated using O2-mediation by t-BuONa. This protocol enables an alternative route for the access to diaryl ketones from benzyl derivatives in good to excellent yields under mild reaction conditions, without transition metal catalysts or additional chemical oxidants.