258506-68-2

Basic information

• Product Name: 3-Chloro-6-trifluoromethyl-pyridazine
• Synonyms: 3-Chloro-6-(trifluoromethyl)pyridazine;3-Chloro-6-(trifluoromethyl)-1,2-diazine;Pyridazine, 3-chloro-6-(trifluoroMethyl)-
• CAS NO: 258506-68-2
• Molecular Formula: C₅H₂ClF₃N₂
• Molecular Weight: 182.53
• Product Categories: Halides;Pyrazines, Pyrimidines & Pyridazines;Pyrazines, Pyrimidines & Pyridazines;Building Blocks;Pyridazine
• Mol File: 258506-68-2.mol
• Article Data: 14

Chemical Properties

• Melting Point: 55-59°C
• Boiling Point: 233.343 °C at 760 mmHg
• Flash Point: 95℃
• Appearance: /
• Density: 1.504
• Vapor Pressure: 0.086mmHg at 25°C
• Refractive Index: 1.445
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: -1.53±0.10(Predicted)
• CAS DataBase Reference: 3-Chloro-6-trifluoromethyl-pyridazine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Chloro-6-trifluoromethyl-pyridazine(258506-68-2)
• EPA Substance Registry System: 3-Chloro-6-trifluoromethyl-pyridazine(258506-68-2)

Safety Data

• Hazard Codes: T
• Statements: 25-36/38
• Safety Statements: 26-45-24/25
• RIDADR: 2811
• WGK Germany: 3
• HazardClass: 6.1
• PackingGroup: Ⅲ
• Hazardous Substances Data: 258506-68-2(Hazardous Substances Data)

Usage

Uses

3-Chloro-6-(trifluoromethyl)pyridazine is a general reagent for use in the repositioning of antitubercular oxazoles for certain neglected tropical diseases.

Chemical Properties

White crystalline powder

InChI:InChI=1/C5H2ClF3N2/c6-4-2-1-3(10-11-4)5(7,8)9/h1-2H

Upstream product

• 135034-10-5 3-chloro-6-iodopyridazine 
• 628332-15-0 6-(trifluoromethyl)-4,5-dihydropyridazin-3(2H)-one 
• 81290-20-2 (trifluoromethyl)trimethylsilane 
• 174607-36-4 6-(trifluoromethyl)pyridazin-3-ol 
• 147531-11-1 trifluoromethanesulfonic acid diphenyl(trifluoromethyl)sulfonium salt 
• 174607-36-4 6-(trifluoromethyl)pyridazin-3(2H)-one 
• 1514-87-0 metyhyl chlorodifluoroacetate 

Downstream Products

• 1048685-30-8 4-(6-trifluoromethyl-pyridazin-3-yl)-piperazine-1-carboxylic acid tert-butyl ester 
• 103317-44-8 1-[3-Chloro-4-(6-trifluoromethyl-pyridazin-3-yloxy)-phenyl]-3-(2-nitro-benzoyl)-urea 
• 1073525-71-9 3,4-dibromo-6-trifluoromethyl-pyridazine 

Relevant articles and documents

COMPOUNDS AND COMPOSITIONS FOR USE IN TREATING SKIN DISORDERS

Provided herein is a compound of formula (XXXII) or a pharmaceutically acceptable salt, solvate, hydrate, stereoisomer thereof or a physiologically functional derivative thereof, wherein R1, R2, R3, G, A, E, n, p, and q are defined herein. Also provided herein are compositions comprising a compound of formula (XXXII), and methods of using a compound of formula (XXXII), e.g., in the treatment or prevention of skin disorders.

PESTICIDALLY ACTIVE TETRACYCLIC HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS

Compounds of formula (I), wherein the substituents are as defined in claim 1, and the agrochemically acceptable salts salts, stereoisomers, enantiomers, tautomers and N-oxides of those compounds, can be used as insecticides and can be prepared in a manner known per se.

PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS

Polycyclic derivatives of formula (I), wherein the substituents are as defined in claim 1, and the agrochemically acceptable salts salts, stereoisomers, enantiomers, tautomers and N-oxides of those compounds, can be used as insecticides and can be prepared in a manner known per se.