292050-43-2

Basic information

• Product Name: 2'-DEOXYXANTHOSINE CEP
• Synonyms: 2'-DEOXYXANTHOSINE CEP;DX CEP
• CAS NO: 292050-43-2
• Molecular Formula: C56H61N8O12P
• Molecular Weight: 1069.12
• Mol File: 292050-43-2.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2'-DEOXYXANTHOSINE CEP(CAS DataBase Reference)
• NIST Chemistry Reference: 2'-DEOXYXANTHOSINE CEP(292050-43-2)
• EPA Substance Registry System: 2'-DEOXYXANTHOSINE CEP(292050-43-2)

Safety Data

• Hazardous Substances Data: 292050-43-2(Hazardous Substances Data)

Upstream product

• 124482-92-4 2-cyanoethyl-N,N-(diisopropylamino)chlorophosphine 
• 292050-45-4 2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-O²,O⁶-bis-[2-(4-nitrophenyl)ethyl]xanthosine 
• 20264-96-4 2-(4-nitrophenyl)ethyl iodide 
• 292050-44-3 3',5'-di-O-acetyl-2'-deoxy-O²,O⁶-bis-[2-(4-nitrophenyl)ethyl]xanthosine 
• 123107-74-4 2'-deoxy-O²,O⁶-bis-[2-(4-nitrophenyl)ethyl]xanthosine 
• 108310-93-6 3',5'-di-O-acetyl-2'-deoxy-O⁶-[2-(4-nitrophenyl)ethyl]xanthosine 
• 108310-92-5 2-amino-6-(2-(p-nitrophenyl)ethyloxy)-9-[2'-deoxy-β-D-erythropentofuranosyl]purine diacetate 

Relevant articles and documents

Synthesis and characterization of oligonucleotides containing 2'- deoxyxanthosine using phosphoramidite chemistry

Oligodeoxynucleotides containing 2'-deoxyxanthosine (X(d)) were synthesized in good yield from a O2,O6-bis[2-(4-nitrophenyl)ethyl](NPE)- protected phosphoramidite of X(d). Attempts to synthesize a O6-monoNPE- protected phosphoramidite resulted in formation of a major by-product. The NPE protecting groups were removed by treatment with oximate ion after, other protecting groups were removed with aqueous NH4OH solution. The composition of the synthetic oligonucleotides was verified by enzymatic degradation and MALDI-TOF mass spectrometry. The efficacy of this procedure allowed isolation of oligodeoxynucleotides containing multiple X(d) residues.