29540-84-9

Basic information

• Product Name: 4-CHLOROPHENYL TRIFLUOROMETHANESULFONATE
• Synonyms: 4-CHLOROPHENYL TRIFLUOROMETHANESULFONATE;4-CHLOROPHENYL TRIFLUOROMETHANESULPHONATE;4-Chlorophenyl trifluoromethanesulphonate 97%;4-Chlorophenyltrifluoromethanesulphonate97%;4-Chlorophenyl triflate
• CAS NO: 29540-84-9
• Molecular Formula: C₇H₄ClF₃O₃S
• Molecular Weight: 260.62
• Mol File: 29540-84-9.mol
• Article Data: 38

Chemical Properties

• Boiling Point: 270.6°Cat760mmHg
• Flash Point: 117.4°C
• Appearance: /
• Density: 1.6g/cm³
• Vapor Pressure: 0.0113mmHg at 25°C
• Refractive Index: 1.49
• CAS DataBase Reference: 4-CHLOROPHENYL TRIFLUOROMETHANESULFONATE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-CHLOROPHENYL TRIFLUOROMETHANESULFONATE(29540-84-9)
• EPA Substance Registry System: 4-CHLOROPHENYL TRIFLUOROMETHANESULFONATE(29540-84-9)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 29540-84-9(Hazardous Substances Data)

Usage

General Description

4-Chlorophenyl trifluoromethanesulfonate, also known as Trifluoromethanesulfonyl chloride, is a chemical compound with the formula C7H4ClF3O2S. It is an organofluorine compound that is often used as a reagent in organic synthesis for the introduction of the trifluoromethanesulfonyl (Tf) group. 4-CHLOROPHENYL TRIFLUOROMETHANESULFONATE is a colorless to light yellow liquid with a pungent odor, and it is highly reactive and can act as a powerful electrophile in various reactions. It is also used in the production of pharmaceuticals, agrochemicals, and materials science, making it an important chemical in the field of organic chemistry.

InChI:InChI=1/C7H4ClF3O3S/c8-5-1-3-6(4-2-5)14-15(12,13)7(9,10)11/h1-4H

Upstream product

• 335-05-7 Trifluoromethanesulfonyl fluoride 
• 17005-59-3 4-chlorophenoxytrimethylsilane 
• 1493-13-6 trifluorormethanesulfonic acid 
• 673-41-6 p-chlorobenzenediazonium tetrafluoroborate 
• 358-23-6 trifluoromethylsulfonic anhydride 
• 106-48-9 4-chloro-phenol 
• 1679-18-1 4-Chlorophenylboronic acid 
• 2926-30-9 sodium triflate 
• 421-83-0 trifluoromethane sulfonyl chloride 
• 288-32-4 1H-imidazole 
• 29540-81-6 1-(trifluoromethylsulfonyl)-1H-imidazole 
• 66107-30-0 4-bromophenyl trifluoromethanesulfonate 
• 17763-67-6 Phenyl triflate 
• 109586-39-2 4-iodophenyl trifluoromethanesulfonate 

Downstream Products

• 5076-63-1 (4-chlorophenyl)diethyl phosphate 
• 106-48-9 4-chloro-phenol 
• 623-03-0 4-Cyanochlorobenzene 
• 623-26-7 terephthalonitrile 
• 142074-93-9 1-(methoxycarbonyl)-5-(4-chlorophenyl)-3-pyrroline 
• 142074-92-8 (R)-(+)-1-(methoxycarbonyl)-5-(4-chlorophenyl)-2-pyrroline 
• 142074-92-8 (S)-(-)-1-(methoxycarbonyl)-5-(4-chlorophenyl)-2-pyrroline 
• 142074-95-1 1-(ethoxycarbonyl)-5-(4-chlorophenyl)-3-pyrroline 
• 142074-94-0 (R)-(+)-1-(ethoxycarbonyl)-5-(4-chlorophenyl)-2-pyrroline 
• 142074-94-0 (S)-(-)-1-(ethoxycarbonyl)-5-(4-chlorophenyl)-2-pyrroline 
• 142074-97-3 1-(phenoxycarbonyl)-5-(4-chlorophenyl)-3-pyrroline 
• 142074-96-2 (R)-(+)-1-(phenoxycarbonyl)-4-(4-chlorophenyl)-2-pyrroline 
• 142074-96-2 (S)-(-)-1-(phenoxycarbonyl)-4-(4-chlorophenyl)-2-pyrroline 
• 33155-59-8 tert-butyl 2-(4-chlorophenyl)acetate 

Relevant articles and documents

Palladium-mediated carboxylation of aryl halides (triflates) or benzyl halides using [13C]/[11C]carbon monoxide with tetrabutylammonium hydroxide or trimethylphenylammonium hydroxide

[Carbonyl-11C]carboxylic acids were synthesised using palladium-mediated reaction of [11C]carbon monoxide with aryl halides/triflates and benzyl halides in combination with either tetrabutylammonium hydroxide or trimethylphenylammoni

Palladium-Catalyzed Reductive Carbonylation of (Hetero) Aryl Halides and Triflates Using Cobalt Carbonyl as CO Source

An efficient protocol for the reductive carbonylation of (hetero) aryl halides and triflates under CO gas-free conditions using Pd/Co2(CO)8 and triethylsilane has been developed. The mild reaction conditions, enhanced chemoselectivity and, easy access to heterocyclic and vinyl carboxaldehydes highlights its importance in organic synthesis.

Base-promoted selective O-phosphorylation of aryl triflates with P(O)-H compounds

Compared to previous transition metal-catalyzed C-phosphorylation reactions for constructing C–P bonds, in the absence of transition metal catalysts and ligands, a direct O-phosphorylation of aryl triflates selectively occurred with P(O)-H compounds in the presence of a base via the construction of O–P bonds. This transformation proceeds under simple and mild conditions, and provides a new method for the preparation of valuable organophosphoryl compounds from readily available P(O)-H compounds and triflates.