30189-51-6Relevant articles and documents
Enhancement of the small intestinal uptake of phenylalanylglycine via a H+/oligopeptide transport system by chemical modification with fatty acids
Fujita, Takuya,Morishita, Yutaka,Ito, Hitomi,Kuribayashi, Daisuke,Yamamoto, Akira,Muranishi, Shozo
, p. 2455 - 2465 (1997)
The transport characteristics of chemically modified phenylalanylglycine (PheGly) with butyric acid (C4-Phe-Gly) and caproic acid (C6-Phe-Gly) were examined using rabbit intestinal brush-border membrane vesicles (BBMVs). In the prese
Synthesis of fully Protected Peptides on a Tetraethyleneglycol Diacrylate (TTEGDA)-Crosslinked Polystyrene support with a Photolytically Detachable 2-Nitrobenzyl Anchoring group
Renil, M.,Pillai, V. N. Rajasekharan
, p. 3809 - 3812 (1994)
1-Chloromethyl-2-nitro tetraethyleneglycol diacrylate (TTEGDA)-crosslinked polystyrene resin was prepared by nitration of chloromethyl (4percent) TTEGDA-crosslinked polystyrene resin and used as a photosensitive solid support for the preparation of fully
Synthesis and conformational characterization of diketopiperazines bearing a benzyl moiety
Nakao, Michiyasu,Toriuchi, Yuriko,Fukayama, Shintaro,Sano, Shigeki
, p. 340 - 342 (2014/03/21)
Diketopiperazines bearing a benzyl moiety with different para-substituents were synthesized and analyzed by 1HNMR spectroscopy. All of these diketopiperazines were found to adopt a folded conformation according to the upfield chemical shift of the cis-proton (cis to the benzyl moiety) due to a shielding effect in the 1HNMR spectra. An intramolecular CH-π interaction appears to be an important factor for the folded conformation due to the effects of para-substituents on the benzyl group.
Phosphorus oxychloride as an efficient coupling reagent for the synthesis of esters, amides and peptides under mild conditions
Chen, Hu,Xu, Xunfu,Liu, Liu,Tang, Guo,Zhao, Yufen
, p. 16247 - 16250 (2013/09/23)
A mild method is described for the conversion of carboxylic acids into esters, amides, as well as peptides without racemization through carboxyl activation by the reagent combination of POCl3 and DMAP. Long chain alcohols could be converted to the corresponding ester in good yields. 31P NMR spectrum was used to detect phosphorus-containing intermediates in ongoing reactions directly, and a possible mechanism has been proposed based on these results. The Royal Society of Chemistry 2013.