33184-20-2Relevant articles and documents
Synthesis of benzofurans from the cyclodehydration of α-phenoxy ketones mediated by Eaton’s reagent
Ma, Lin,Ma, Zhanwei,Zhang, Min,Zhou, Min
, p. 426 - 436 (2020/03/23)
Cyclodehydration of α-phenoxy ketones promoted by Eaton’s reagent (phosphorus pentoxide–methanesulfonic acid) is used to prepare 3-substituted or 2,3-disubstituted benzofurans with moderate to excellent yields under mild conditions. The method provides a facile access to benzofurans from readily available starting materials such as phenols and α-bromo ketones. The reaction is highly efficient, which is attributed to the good reactivity and fluidity of Eaton’s reagent. The reaction can be applied to prepare naphthofurans, furanocoumarins, benzothiophenes, and benzopyrans.
Metal-Free Synthesis of Furocoumarins: An Approach via Iodine-Promoted One-Pot Cyclization between 4-Hydroxycoumarins and Acetophenones
Pham, Phuc H.,Nguyen, Que T. D.,Tran, Nhu K. Q.,Nguyen, Vu H. H.,Doan, Son. H.,Ha, Hiep Q.,Truong, Thanh,Phan, Nam T. S.
, p. 4431 - 4435 (2018/09/11)
A transition metal-free approach was developed to achieve substituted furocoumarins via an iodine-promoted one-pot cyclization between 4-hydroxycoumarins and acetophenones. High yields of furocoumarins were achieved in the presence of NH4OAc as
Copper-catalyzed radical/radical cross-coupling of ketoxime carboxylates with 4-hydroxycoumarins: A novel synthesis of furo[3,2-c]-coumarins
He, Mingchuang,Yan, Zhaohua,Wang, Wangyang,Zhu, Fuyuan,Lin, Sen
, p. 3706 - 3712 (2018/09/12)
A novel and efficient strategy for the synthesis of furo[3,2-c]coumarins has been developed via copper-catalyzed radical/radical cross-coupling of ketoxime carboxylates with 4-hydroxycoumarins. This redox-neutral reaction allows smooth and selective synthesis of 2-substituted, 3-substituted, 2,3-disubstituted and 2,3-fused polycyclic furo[3,2-c]coumarins.
