7257-94-5Relevant articles and documents
Novel preparation and reactivity of poly[4-hydroxy(tosyloxy)iodo]styrenes
Abe,Sakuratani,Togo
, p. 22 - 24 (2001)
Poly[4-hydroxy(tosyloxy)iodo]styrene (high M.W.) and poly{α-methyl[4-hydroxy(tosyloxy)iodo]styrene} (low M.W.) were prepared from polystyrene (average M.W. = 45,000) and poly(α-methylstyrene) (average M.W. = 6,200), respectively, and their reactivities fo
Iridium(III)-Catalyzed Tandem Annulation of Pyridine-Substituted Anilines and α-Cl Ketones for Obtaining 2-Arylindoles
Cui, Xin-Feng,Qiao, Xin,Wang, He-Song,Huang, Guo-Sheng
, p. 13517 - 13528 (2020/12/15)
A facile and expeditious protocol for the synthesis of 2-arylindole compounds from readily available N-(2-pyridyl)anilines and commercially available α-Cl ketones through iridium-catalyzed C-H activation and cyclization is reported here. As a complementary approach to the conventional strategies for indole synthesis, the transformation exhibits powerful reactivity, tolerates a large number of functional groups, and proceeds with good to excellent yields under mild conditions, providing a straightforward method to obtain structurally diverse and valuable indole scaffolds. Furthermore, the reaction could be easily scaled up to gram scale.
Continuous-Flow Electrochemical Generator of Hypervalent Iodine Reagents: Synthetic Applications
Elsherbini, Mohamed,Winterson, Bethan,Alharbi, Haifa,Folgueiras-Amador, Ana A.,Génot, Célina,Wirth, Thomas
supporting information, p. 9811 - 9815 (2019/06/24)
An efficient and reliable electrochemical generator of hypervalent iodine reagents has been developed. In the anodic oxidation of iodoarenes to hypervalent iodine reagents under flow conditions, the use of electricity replaces hazardous and costly chemical oxidants. Unstable hypervalent iodine reagents can be prepared easily and coupled with different substrates to achieve oxidative transformations in high yields. The unstable, electrochemically generated reagents can also easily be transformed into classic bench-stable hypervalent iodine reagents through ligand exchange. The combination of electrochemical and flow-chemistry advantages largely improves the ecological footprint of the overall process compared to conventional approaches.