3409-96-9

Basic information

• Product Name: Benzamide, N-methyl-N-(phenylsulfonyl)-
• Synonyms: benzenesulfonyl-benzoyl-methyl-amine;Benzolsulfonyl-benzoyl-methyl-amin;N-Methyl-N-benzoyl-benzolsulfamid;N-Benzolsulfonyl-N'-isopropyl-harnstoff;N-benzenesulfonyl-N'-isopropyl-urea;N-Benzolsulfonyl-N-methyl-benzamid
• CAS NO: 3409-96-9
• Molecular Formula: C14H13NO3S
• Molecular Weight: 275.328
• Mol File: 3409-96-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzamide, N-methyl-N-(phenylsulfonyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, N-methyl-N-(phenylsulfonyl)-(3409-96-9)
• EPA Substance Registry System: Benzamide, N-methyl-N-(phenylsulfonyl)-(3409-96-9)

Safety Data

• Hazardous Substances Data: 3409-96-9(Hazardous Substances Data)

Upstream product

• 3559-04-4 N-benzoyl-benzenesulfonamide 
• 74-88-4 methyl iodide 
• 5183-78-8 methyl(phenylsulfonyl)amide 
• 98-88-4 benzoyl chloride 

Downstream Products

• 92-52-4 biphenyl 
• 29019-38-3 N,N'-dimethylbenzoamidine 
• 93-98-1 N-phenyl benzoyl amide 
• 5183-78-8 methyl(phenylsulfonyl)amide 
• 2397-29-7 N-methyl-N′-phenylbenzimidamide 
• 936-49-2 2-phenyl-2-imidazoline 
• 34028-17-6 N-methylbenzamidine 
• 21010-63-9 N,N'-dibenzyl-benzamidine 
• 85522-27-6 N-ethyl-N'-methyl-benzamidine 
• 25092-88-0 N¹,N²,N³-trimethylbenzamidine 
• 1775-72-0 1-(N-methyl-benzimidoyl)-piperidine 

Relevant articles and documents

N-Aroylsulfonamide-Photofragmentation (ASAP)-A Versatile Route to Biaryls

The photochemical fragmentation of N-aroylsulfonamides 9 (ASAP) is a powerful method for the preparation of various biaryls. Compounds 9 are easily accessible in two steps from amines by treatment with arenesulfonyl chlorides and aroyl chlorides. Many of these compounds were prepared for the first time. The irradiation takes place in a previously developed continuous-flow reactor using inexpensive UVB or UVC fluorescent lamps. Isocyanates and sulphur dioxide are formed as the only by-products. The ASAP tolerates a variety of functional groups and is even suited for the preparation of phenylnaphthalenes and terphenyls. The ASAP mechanism was elucidated by interaction of photophysical and quantum chemical (DFT) methods and revealed a spirocyclic biradical as key intermediate.

β-Keto sulfones as inhibitors of 11β-hydroxysteroid dehydrogenase type I and the mechanism of action

The design, synthesis, and biological evaluation of β-keto sulfones as 11β-HSD1 inhibitors and the mechanism of inhibition are described here. This class of compounds is not active against 11β-HSD2 and therefore may have therapeutic potential for metabolic syndrome and type 2 diabetes.