3522-98-3

Basic information

• Product Name: 4-Methylenepiperidine hydrobroMide
• Synonyms: 4-Methylenepiperidine hydrobroMide;4-METHYLENEPIPERIDINE HBR
• CAS NO: 3522-98-3
• Molecular Formula: C6H12BrN
• Molecular Weight: 178.07018
• EINECS: -0
• Mol File: 3522-98-3.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-Methylenepiperidine hydrobroMide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Methylenepiperidine hydrobroMide(3522-98-3)
• EPA Substance Registry System: 4-Methylenepiperidine hydrobroMide(3522-98-3)

Safety Data

• Hazardous Substances Data: 3522-98-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
4-Methylenepiperidine hydrobromide is used as a key intermediate in the synthesis of various drugs for its versatile chemical properties. It contributes to the production of local anesthetics, muscle relaxants, and antihistamines, enhancing their therapeutic effects and improving patient outcomes.
Used in Agrochemical Industry:
4-Methylenepiperidine hydrobromide is used as a building block in the creation of pesticides and herbicides, providing a foundation for developing effective and targeted agricultural chemicals. Its role in this industry helps to increase crop yields and protect plants from pests and diseases.
Used in Organic Synthesis:
4-Methylenepiperidine hydrobromide is used as a valuable intermediate in organic synthesis, allowing for the development of new compounds and materials with diverse applications across various industries. Its versatility and reactivity make it an essential component in the synthesis of complex organic molecules.

Upstream product

• 159635-49-1 tert-butyl 4-methylidenepiperidine-1-carboxylate 
• 3592-25-4 1,5-dichloropentan-3-one 
• 140200-76-6 α,α'-dibromopentan-3-one 
• 148133-82-8 4-methylene piperidine 

Relevant articles and documents

Preparation method of 4-methylpiperidine salt

The invention relates to a preparation method of 4-methylpiperidine salt. According to the invention, 1,5-dihalide-3-pentanone is used as an initial raw material, through a wittig reaction, halogenated amine hydrolysis, salt forming with acid, the 4-methylpiperidine salt is obtained with high efficiency. The preparation method has the beneficial effects that the raw material source is wide, cost is low, operation is simple, a solvent is recycled and reused, the waste liquid discharge capacity is less, the product recovery rate is high, and industrialization is easily realized.

Method for preparation of Efinaconazole

The invention provides a method for preparation of Efinaconazole. The method comprises the following step: in the presence of iodide or its hydrate, in a reaction solvent and alkali, a compound as shown in the formula 2 is contacted with a compound as sho

PROCESS FOR PRODUCING 1-TRIAZOLE-2-BUTANOL DERIVATIVES

An object is to provide a process for producing the compound of formula 1 in higher yield by the ring-opening addition reaction of epoxytriazole with amine under mild conditions without using a large excess of 4-methylenepiperidine. The process for producing (2R,3R)-2-(2,4-difluorophenyl)-3-(4-methylenepiperidin-1-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol or an acid addition salt thereof comprises reacting (2R,3S)-2-(2,4-difluorophenyl)-3-methyl-2-[(1H-1,2,4-triazol-1-yl)methyl]oxirane with an acid addition salt of 4-methylenepiperidine in a reaction solvent in the presence of a hydroxide of an alkali metal or an alkaline earth metal selected from the group consisting of lithium, sodium, calcium, and strontium, or a hydrate thereof.