39939-07-6

Basic information

• Product Name: 5-(benzyloxymethyl)cyclopentadiene
• Synonyms: 5-(benzyloxymethyl)cyclopentadiene
• CAS NO: 39939-07-6
• Molecular Weight: 186.254
• Mol File: 39939-07-6.mol
• Article Data: 20

Chemical Properties

• Boiling Point: 271.9±9.0 °C(Predicted)
• Density: 1.035±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 5-(benzyloxymethyl)cyclopentadiene(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(benzyloxymethyl)cyclopentadiene(39939-07-6)
• EPA Substance Registry System: 5-(benzyloxymethyl)cyclopentadiene(39939-07-6)

Safety Data

• Hazardous Substances Data: 39939-07-6(Hazardous Substances Data)

Upstream product

• 100-51-6 benzyl alcohol 
• 542-92-7 cyclopenta-1,3-diene 
• 3587-60-8 Benzyloxymethyl chloride 
• 34822-90-7 cyclopentadienylthallium 

Downstream Products

• 147420-88-0 1-<(benzyloxy)methyl>-2-azabicyclo<2.2.1>hept-5-en-3-one 
• 140440-31-9 7-anti-<(benzyloxy)methyl>-2-azabicyclo<2.2.1>hept-5-en-3-one 
• 140440-30-8 7-syn-<(benzyloxy)methyl>-2-azabicyclo<2.2.1>hept-5-en-3-one 
• 121809-01-6 (-)-3-(7'-Benzyloxymethyl-bicyclo<2.2.1>hept-5'-ene-2'-carbonyl)-1,3-oxazolin-2-one 
• 121809-01-6 3-((1S,2R,4R,7S)-7-Benzyloxymethyl-bicyclo[2.2.1]hept-5-ene-2-carbonyl)-oxazolidin-2-one 
• 54347-95-4 4-Benzyloxymethyl-5-chlor-5-cyano-2-norbornen 
• 188399-48-6 (1R,2S)-2-((benzyloxy)methyl)cyclopent-3-en-1-ol 
• 207516-06-1 (S)-N-((1R,4S,5R)-5-Benzyloxymethyl-4-hydroxy-cyclopent-2-enyl)-2-hydroxy-2-phenyl-acetamide 
• 160868-00-8 (3aR,4R,5S,6R,6aS)-4-Hydroxymethyl-2-((2S,3R,4S,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-ylamino)-4,5,6,6a-tetrahydro-3aH-cyclopentaoxazole-4,5,6-triol 
• 160401-04-7 1-((1R,2R,3S,4S,5S)-2,3,4,5-Tetrahydroxy-2-hydroxymethyl-cyclopentyl)-3-((2S,3R,4S,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl)-thiourea 
• 207516-57-2 (1S,4R,5R)-4-Amino-5-benzyloxymethyl-cyclopent-2-enol 
• 207516-59-4 N-((1R,4S,5R)-5-Benzyloxymethyl-4-hydroxy-cyclopent-2-enyl)-2,2,2-trichloro-acetamide 
• 207516-60-7 N-((1S,2S,3R,4R,5R)-3-Benzyloxymethyl-4-hydroxy-6-oxa-bicyclo[3.1.0]hex-2-yl)-2,2,2-trichloro-acetamide 
• 207516-46-9 Acetic acid (1S,2S,3R,5S)-3-acetoxy-2-bromo-4-methylene-5-phenylacetylamino-cyclopentyl ester 

Relevant articles and documents

PCSK9 INHIBITORS AND METHODS OF USE THEREOF

The invention relates to a novel inhibitor pharmacophore of PCSK9 and heteroaryl compounds that bind the PCSK9 protein.

Novel spirocyclic systems via multicomponent aza-Diels-Alder reaction

Here we present a two-step diastereoselective methodology building on a multicomponent aza-Diels-Alder reaction. Using previously unexplored cyclic ketones, heterocyclic amines and cyclopentadiene derivatives, we obtained novel spiro-heterocyclic frameworks at the interphase between drug-like molecules and natural products.

Cis,cis,cis,cis-1,2,3,4,5-Pentakis(hydroxymethyl)cyclopentane

All-cis pentamethanolcyclopentane has been obtained in six steps by Diels-Alder condensation of maleic anhydride with (benzyloxymethyl)cyclopenta-2, 4-diene, reduction of the anhydride to a diol that was protected as the acetonide. Then, ozonolysis of the double bond, followed by reduction led to a cis-diol. Then successive deprotections of the three other methanol groups gave the cis,cis,cis,cis-1,2,3,4,5-pentakis(hydroxymethyl)cyclopentane.