110567-21-0Relevant articles and documents
PCSK9 INHIBITORS AND METHODS OF USE THEREOF
-
Page/Page column 146-147, (2020/07/31)
The invention relates to a novel inhibitor pharmacophore of PCSK9 and heteroaryl compounds that bind the PCSK9 protein.
STING MODULATOR COMPOUNDS, AND METHODS OF MAKING AND USING
-
, (2019/05/30)
The present disclosure provides STING modulators/agonists, and methods of synthesis and methods for using for the prophylaxis or treatment of cancer and other STING-related diseases. The present disclosure relates to a compound represented by the Formula (I): wherein each symbol is as defined in the description, or a pharmaceutically acceptable salt thereof.
The synthesis of possible transition state analogue inhibitors of thymidine phosphorylase
Evans, Gary B.,Gainsford, Graeme J.,Schramm, Vern L.,Tyler, Peter C.
, p. 406 - 409 (2015/04/27)
The synthetically challenging SN2 transition state mimic for thymidine phosphorylase, along with its phosphonate analogue, were synthesised via a modified Corey-Link reaction in good overall yields and ensuring the correct stereochemical outcome.