4190-14-1

Basic information

• Product Name: N-(2-OXO-2-PHENYLETHYL)BENZAMIDE
• Synonyms: N-(2-OXO-2-PHENYLETHYL)BENZAMIDE;N-Phenacylbenzamide;N-(2-keto-2-phenyl-ethyl)benzamide
• CAS NO: 4190-14-1
• Molecular Formula: C₁₅H₁₃NO₂
• Molecular Weight: 239.26922
• Mol File: 4190-14-1.mol
• Article Data: 22

Chemical Properties

• Melting Point: 125 °C
• Boiling Point: 478.9 °C at 760 mmHg
• Flash Point: 197.2 °C
• Appearance: /
• Density: 1.163 g/cm³
• Vapor Pressure: 2.48E-09mmHg at 25°C
• Refractive Index: 1.59
• PKA: 13.10±0.46(Predicted)
• CAS DataBase Reference: N-(2-OXO-2-PHENYLETHYL)BENZAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-OXO-2-PHENYLETHYL)BENZAMIDE(4190-14-1)
• EPA Substance Registry System: N-(2-OXO-2-PHENYLETHYL)BENZAMIDE(4190-14-1)

Safety Data

• Hazardous Substances Data: 4190-14-1(Hazardous Substances Data)

Usage

General Description

N-(2-oxo-2-phenylethyl)benzamide is a chemical compound with the molecular formula C15H13NO2. It is a benzamide derivative that contains a phenylethyl group linked to a benzene ring. N-(2-OXO-2-PHENYLETHYL)BENZAMIDE is used in various research and laboratory settings as a reagent and intermediate in the synthesis of pharmaceuticals and other organic compounds. It has also been studied for its potential pharmacological properties, including its ability to interact with biological targets and its potential as a drug candidate. The compound's specific applications and properties may vary depending on the context in which it is used.

InChI:InChI=1/C15H13NO2/c17-14(12-7-3-1-4-8-12)11-16-15(18)13-9-5-2-6-10-13/h1-10H,11H2,(H,16,18)

Upstream product

• 34119-82-9 2-(benzoylamino)-1-phenylethanol 
• 1816-88-2 2-azido-1-phenylethan-1-one 
• 14850-88-5 benzoylhydrazone of benzaldehyde 
• 70-11-1 α-bromoacetophenone 
• 16717-64-9 1-azidostyrene 
• 65-85-0 benzoic acid 
• 495-69-2 Hippuric Acid 
• 64-04-0 phenethylamine 
• 98-88-4 benzoyl chloride 
• 613-89-8 2-Aminoacetophenone 
• 7568-93-6 2-Amino-1-phenylethanol 
• 774559-32-9 C₂₂H₁₈N₂O₂ 
• 536-38-9 4-chlorobenzoylmethyl bromide 
• 26086-60-2 2-azido-4'-chloroacetophenone 

Downstream Products

• 151255-57-1 3-(2-oxo-2-phenyl-ethyl)-benzo[e][1,3]oxazine-2,4-dione 
• 41542-84-1 N-(1-hydroxymethyl-2-oxo-2-phenyl-ethyl)-benzamide 
• 111059-46-2 (-)-N-benzoyl-2-hydroxy-2-phenylethylamine 
• 1239496-79-7 4-benzyl-2,5-diphenylthiazole 
• 30057-74-0 N-(1-oxo-1,3-diphenylpropan-2-yl)benzamide 
• 1448154-38-8 N-(5-methyl-2-phenyl-1H-pyrrol-3-yl)benzamide 
• 1448154-41-3 N-(2,5-diphenyl-1H-pyrrol-3-yl)benzamide 
• 1448154-36-6 N-(2-phenyl-1H-pyrrol-3-yl)benzamide 

Relevant articles and documents

Muricatisine - A new alkaloid from two species of Oxytropis

The new alkaloid muricatisine has been isolated from the epigeal parts of the plants Oxytropis muricata (Pall.) DC. (Mongolia) and O. puberula Boriss. (Kazakhstan), which belong to the Fabaceae family, and its structure has been established on the basis of spectral characteristics as N-benzoyl-2-oxo-2-phenylethylamine and has been confirmed by a partial synthesis.

Synthesis of α-Amidoketones through the Cascade Reaction of Carboxylic Acids with Vinyl Azides under Catalyst-Free Conditions

An efficient synthesis of α-amidoketone derivatives through the cascade reactions of carboxylic acids with vinyl azides is presented. Compared with literature protocols, notable features of this new method include catalyst-free conditions, broad substrate scope, good tolerance of a wide range of functional groups, and high efficiency. In addition, the synthetic potential of this method as a tool for late-stage modification was convincingly manifested by its application in the structural elaborations of a number of carboxylic acid drug molecules.

Remote C(sp3)-H Oxygenation of Protonated Aliphatic Amines with Potassium Persulfate

This letter describes the development of a method for selective remote C(sp3)-H oxygenation of protonated aliphatic amines using aqueous potassium persulfate. Protonation serves to deactivate the proximal C(sp3)-H bonds of the amine substrates and also renders the amines soluble in the aqueous medium. These reactions proceed under relatively mild conditions (within 2 h at 80 °C with amine as limiting reagent) and do not require a transition metal catalyst. This method is applicable to a variety of types of C(sp3)-H bonds, including 3°, 2°, and benzylic C-H sites in primary, secondary, and tertiary amine substrates.