420107-66-0Relevant articles and documents
The first synthesis of kaitocephalin based on the structure revision
Watanabe, Hidenori,Okue, Masayuki,Kobayashi, Hiroyuki,Kitahara, Takeshi
, p. 861 - 864 (2007/10/03)
A total synthesis of kaitocephalin (2), a glutamate receptor antagonist, was accomplished employing a novel stereoselective C-C bond forming reaction of a nitrone (8) and a halide (11) with zinc in aqueous solvent under sonication as a key step. The absolute configuration of kaitocephalin was confirmed to be 2R,3S,4R,7R,9S.