4341-34-8

Basic information

• Product Name: 2-(2-Thiophenylmethyl)thiophene
• Synonyms: 2,2'-METHYLENEDITHIOPHENE;2-(2-Thienylmethyl)thiophene;Bis(2-thienyl)methane;Di-2-Thienylmethane;Thiophene, 2,2'-methylenebis-;Thiophene, 2,2'-methylenedi-;2-(2-thiophenylmethyl)thiophene;2,2'-Dithienylmethane
• CAS NO: 4341-34-8
• Molecular Formula: C₉H₈S₂
• Molecular Weight: 180.29
• Mol File: 4341-34-8.mol

Chemical Properties

• Melting Point: 44.0 to 48.0 °C
• Boiling Point: 267°C(lit.)
• Flash Point: 81.3°C
• Appearance: /
• Density: 1.219g/cm³
• Vapor Pressure: 0.0185mmHg at 25°C
• Refractive Index: 1.626
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-(2-Thiophenylmethyl)thiophene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-Thiophenylmethyl)thiophene(4341-34-8)
• EPA Substance Registry System: 2-(2-Thiophenylmethyl)thiophene(4341-34-8)

Safety Data

• Hazardous Substances Data: 4341-34-8(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
2-(2-Thiophenylmethyl)thiophene is utilized as a key intermediate in the synthesis of complex organic molecules, contributing to the development of novel chemical entities with potential applications in various fields.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, 2-(2-Thiophenylmethyl)thiophene serves as a crucial component in the formulation of new drugs. Its unique structural features allow it to be incorporated into medicinal compounds, potentially enhancing their therapeutic effects and selectivity.
Used in Agrochemical Industry:
2-(2-Thiophenylmethyl)thiophene is also employed in the agrochemical industry, where it is used to develop new pesticides and other crop protection agents. Its chemical properties make it a valuable asset in the design of effective and environmentally friendly agrochemicals.
Used in Optoelectronic Devices:
Recognized for its potential in the field of optoelectronics, 2-(2-Thiophenylmethyl)thiophene is explored for its application in organic light-emitting diodes (OLEDs) and organic photovoltaic devices. Its electronic properties make it a promising candidate for improving the performance and efficiency of these devices.

InChI:InChI=1/C9H8S2/c1-3-8(10-5-1)7-9-4-2-6-11-9/h1-6H,7H2

Upstream product

• 110-88-3 1,3,5-Trioxan 
• 188290-36-0 thiophene 
• 765-50-4 2-Chloromethylthiophene 
• 50-00-0 formaldehyd 
• 109-87-5 Dimethoxymethane 
• 704-38-1 di(thiophen-2-yl)methanone 
• 636-72-6 2-thiophenemethanol 
• 5271-67-0 2-Thiophenecarbonyl chloride 

Downstream Products

• 35250-77-2 5-(2-thienylmethyl)-thiophene-2-carbaldehyde 
• 4408-82-6 2,2-di(thiophen-2-yl)acetic acid 
• 106181-18-4 2-Benzyl-5-thenylthiophene 
• 106181-25-3 2,2'-(2-phenylethane-1,1-diyl)dithiophene 
• 19629-78-8 16-phenyl-hexadecanoic acid 
• 106181-23-1 16-phenylhexadecanoic acid methyl ester 
• 106181-20-8 6-(5-(5-Benzyl-2-thenyl)-2-thienyl)hexanoic Acid 
• 106181-19-5 5-(5-(5-Benzyl-2-thenyl)-2-thienoyl)pentanoic Acid 
• 6250-70-0 1,19-nonadecanedioic acid 
• 364328-98-3 2-triphenylstannyl-5-[(5-triphenylstannylthien-2-yl)methyl]thiophen 
• 1228246-25-0 1,1,6,6-tetra(thiophen-2-yl)hexane 
• 1228246-22-7 1-(3,4-dimethoxyphenyl)-2,2-di(thiophen-2-yl)ethanol 

Relevant articles and documents

Solid-state photoreaction in two-component molecular crystals of thienylacetic acids and aza aromatic compounds

A series of two-component molecular crystals of 2-thienylacetic acid (1) or bis(2-thienyl)acetic acid (2) with aza aromatic compounds such as acridine (a) and phenanthridine (b) were prepared by crystallization from the solutions of both components. Irradiation of the crystals caused photodecarboxylation and radical intermediates which give decarboxylated and condensation products. The relationship between the crystal structures and the reaction paths are discussed. (C) 2000 Elsevier Science Ltd.

AZA-PYRIDONE COMPOUNDS AND USES THEREOF

Disclosed herein are aza-pyridone compounds, pharmaceutical compositions that include one or more aza-pyridone compounds, and methods of synthesizing the same. Also disclosed herein are methods of ameliorating and/or treating a disease and/or a condition, including an orthomyxovirus infection, with an aza-pyridone compound. Examples of an orthomyxovirus viral infection include an influenza infection.

Melamine trisulfonic acid: A new efficient catalyst for the synthesis of aryldithienylmethanes

An efficient method has been developed for the synthesis of dithienylmethanes via bisarylation of aldehydes with thiophene in the presence of melamine trisulfonic acid as a catalyst under solvent-free conditions.

Efficient synthesis of triarylmethanes via bisarylation of aryl aldehydes with arenes catalyzed by silica gel-supported sodium hydrogen sulfate

An efficient synthesis of triarylmethanes has been developed via bisarylation of aryl aldehydes with arenes catalyzed by silica gel-supported sodium hydrogen sulfate in a solvent-free system. The new method features high yield, mild reaction conditions, a

Conjugated Macrocycles Related to the Porphyrins. Part 3. Acid Catalyzed Condensations of Thiophenecarboxaldehydes with a Dipyrrylmethane

McDonald condensation of a dipyrrylmethanedicarboxylic acid 3b with 2,2'-dithienylmethane-5,5'-dicarboxaldehyde (2b) failed to give the expected dithiophene porphyrin analog 1b.However, oxidation of the reaction mixtures with DDQ gave trace amounts of porphyrin-like materials.Model studies indicate that these fractions are meso-dithienylporphyrins.The synthesis of three related α,γ-disubstituted porphyrins is described.

Photochemical reactions of Thienyl-, Bithienyl-, Terthienyl- and Thienylaroyl-methanols

Photochemical reactions of some thienyl-, bithienyl-, terthienyl- and thienylaroyl-methanols were studied in the neat state as well as in solvents like methanol and benzene.The terthienylmethanols were found to be susceptible to photo-sensitized oxidation which was inhibited by singlet oxygen quenchers.The photoproducts were isolated, characterised by spectroscopic methods and in some cases by synthesis.

SYNTHESIS OF 16-(4-IODOPHENYL)HEXADECANOIC ACID

16-(4-Iodophenyl)hexadecanoic acid was prepared in six steps by two methods: from 6-(2-thienyl)hexanoic acid and 6-phenylhexanoyl chloride or by alkylation, or acylation, of 2-thienylthiophene.Mass and 1H NMR spectra of some prepared compounds are discussed.The synthesis is suitable for preparation of radioactively labelled acids used as myocardial imaging agents.

BASE CLEAVAGE OF SUBSTITUTED - AND -TRIMETHYLSILANE. STABILIZATION OF CARBANIONIC CENTRES BY 2-THIENYL AND 2-FURYL GROUPS

Rates of cleavage by NaOMe-MeOH at 25 deg C have been determined for (2-thienyl)2CHSiMe3 and for the compounds Ph(2-thienyl)CHSiMe3 and Ph(2-furyl)CHSiMe3 and some of their derivatives with a substituent in the m- or p-position of the phenyl group or the