460-25-3

Basic information

• Product Name: 1,3-DIBROMO-1,1-DIFLUOROPROPANE
• Synonyms: 1,3-DIBROMO-1,1-DIFLUOROPROPANE;1,3-Dibromo-1,1-difluoropropane 98%;1,3-Dibromo-1,1-difluoropropane98%;Dibromodifluoropropane
• CAS NO: 460-25-3
• Molecular Formula: C₃H₄Br₂F₂
• Molecular Weight: 237.87
• Mol File: 460-25-3.mol

Chemical Properties

• Boiling Point: 62°C 86mm
• Flash Point: 32.2 °C
• Appearance: /
• Density: 2.037
• Vapor Pressure: 12.3mmHg at 25°C
• Refractive Index: 1.4492
• CAS DataBase Reference: 1,3-DIBROMO-1,1-DIFLUOROPROPANE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-DIBROMO-1,1-DIFLUOROPROPANE(460-25-3)
• EPA Substance Registry System: 1,3-DIBROMO-1,1-DIFLUOROPROPANE(460-25-3)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 460-25-3(Hazardous Substances Data)

Usage

Synthesis Reference(s)

The Journal of Organic Chemistry, 45, p. 2273, 1980 DOI: 10.1021/jo01299a055

InChI:InChI=1/C3H4Br2F2/c4-2-1-3(5,6)7/h1-2H2

Upstream product

• 74-85-1 ethene 
• 75-61-6 dibromodifluoromethane 
• 430-85-3 1,1-dibromo-2,2-difluoroethylene 

Downstream Products

• 460-32-2 3-bromo-1,1,1-trifluoropropane 
• 420-90-6 3-bromo-3,3-difluropropene 
• 60917-29-5 1,1-difluoro-3-bromo-1-propene 
• 73557-48-9 1-(1,1-difluoro-2-propenyl)cyclohexanol 
• 73557-49-0 3,3-Difluoro-2-phenyl-pent-4-en-2-ol 
• 64545-26-2 3,3-difluoro-3-(dimethylphenylsilyl)propene 
• 1309089-27-7 C₁₃H₁₃F₂NO₄ 
• 1309089-28-8 C₁₆H₁₅F₄NO₄ 

Relevant articles and documents

Method of synthesizing fluorinated diene alcohols

Disclosed are fluorinated diene alcohols perferably having a fluorine content of at least about 45 weight percent and having a plurality of moieties of the formula CFx and a plurality of moieties of the formula CHx, where each x is independently 1, 2 or 3 and where each CFx moiety is not directly bonded to another CFx moiety. Methods of synthesizing fluorinated diene alcohol compounds are also disclosed comprising reacting at least one C2-C3 alkene halide with at least one reactant of the formula (II): where Z is OH, OR6, OC(O)R7, or a halogen, R6 is a C1-C6 branched or straight chain alkyl, and R7 is a C1-C6 branched or straight chain alkyl or fluoroalkyl,

Copper salt-catalysed reaction of perfluoroalkyl halides with olefins

Perfluoroalkyl halides react with olefins in the presence of copper acetate and hydrazine to give 1,2-addition products.

gem-(DIFLUOROALLYL)LITHIUM: PREPARATION BY LITHIUM-HALOGEN EXCHANGE AND UTILIZATION IN ORGANOSILICON AND ORGANIC SYNTHESIS.

gem-(Difluoroallyl)lithium may be generated by lithium-bromine exchange between n-butyllithium and CH//2 equals CHCF//2Br at minus 95 degree C by using an in situ procedure. When this preparation is carried out in the presence of chlorosilanes, aldehydes, ketones, and esters, products are formed, often in good yield. The factors determining the regioselectivity in addition to C equals O of unsymmetrically substituted allylic lithium reagents are discussed.

gem-Difluoroallyllithium: Improved Synthesis Brings Improved Applicability

The action of n-butyllithium in hexane on CF2BrCH=CH2/CF2=CHCH2Br (5:2 to 20:1 mixture) in 5:1:1 THF/Et2O/pentane at -95 deg C generates gem-difluoroallyllithium which may be trapped, generally in good yield, by an in situ procedure using triorganochlorosilanes (R3SiCF2CH=CH2) and aldehydes and ketones (RR'C(OH)CF2CH=CH2).