4879-95-2

Basic information

• Product Name: beta-Isovalerolactam
• Synonyms: beta-Isovalerolactam;4,4-Dimethyl-2-azetidinone;2-Azetidinone, 4,4-diMethyl-;4,4-DIMETHYLAZETIDIN-2-ONE
• CAS NO: 4879-95-2
• Molecular Formula: C₅H₉NO
• Molecular Weight: 99.13106
• Mol File: 4879-95-2.mol

Chemical Properties

• Melting Point: 166-172 °C
• Boiling Point: 212.1 °C at 760 mmHg
• Flash Point: 107.8 °C
• Appearance: /
• Density: 0.972 g/cm³
• Storage Temp.: Sealed in dry,Store in freezer, under -20°C
• PKA: 15.99±0.40(Predicted)
• CAS DataBase Reference: beta-Isovalerolactam(CAS DataBase Reference)
• NIST Chemistry Reference: beta-Isovalerolactam(4879-95-2)
• EPA Substance Registry System: beta-Isovalerolactam(4879-95-2)

Safety Data

• Hazardous Substances Data: 4879-95-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
Beta-Isovalerolactam is utilized as a precursor in the synthesis of various pharmaceuticals and agrochemicals, contributing to the development of new drugs and pesticides. Its unique chemical structure allows it to be a key component in creating molecules with specific therapeutic or pesticidal properties.
Used in Polymer Production:
As an intermediate in the production of polymers, Beta-Isovalerolactam plays a crucial role in the manufacturing process of materials like nylon. Its involvement in polymer chemistry aids in the creation of versatile and durable polymers used in a wide range of applications, from textiles to engineering plastics.
Used in Organic Chemistry Research:
Beta-Isovalerolactam has been studied for its potential as a chiral catalyst in organic chemistry reactions. Its unique properties make it a promising candidate for enhancing the selectivity and efficiency of various chemical processes, leading to advancements in the synthesis of enantiomerically pure compounds.

Upstream product

• 715-27-5 1-benzoyl-4,4-dimethyl-azetidin-2-one 
• 625-05-8 3-amino-3-methylbutanoic acid 

Downstream Products

• 80541-89-5 (+/-)-3-azido-1-t-butyldiphenylsilyl-4,4-dimethyl-2-azetidinone 
• 145455-23-8 L-158432 
• 1026422-80-9 3-<(tert-butoxycarbonyl)amino>-3-methyl-N-<2,3,4,5-tetrahydro-2-oxo-1-<<2'-<1,1'-biphenyl>-4-yl>methyl>-1H-1-benzazepin-3(R)-yl>butanamide 
• 1059656-14-2 (1,1-Dimethyl-2-{2-oxo-1-[2'-(1-trityl-1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-1,2,3,4,5,6-hexahydro-benzo[b]azocin-3-ylcarbamoyl}-ethyl)-carbamic acid tert-butyl ester 
• 1062320-30-2 (1,1-Dimethyl-2-{2-oxo-1-[2'-(1-trityl-1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-1,2,3,4-tetrahydro-quinolin-3-ylcarbamoyl}-ethyl)-carbamic acid tert-butyl ester 
• 145485-79-6 tert-butyl 4'-<<3-<(3-tert-butoxycarbonyl)amino>-3-methyl-1-oxobutyl>amino>-<<2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepin-1-yl>methyl><1,1'-biphenyl>-2-carboxylate 
• 80541-88-4 (+/-)-1-butyldiphenylsilyl-4,4-dimethyl-2-azetidinone 
• 2658-24-4 2,2-dimethylaziridine 
• 187737-37-7 propene 
• 74-84-0 ethane 
• 75-28-5 Isobutane 
• 201230-82-2 carbon monoxide 
• 115-11-7 isobutene 
• 625-05-8 3-amino-3-methylbutanoic acid 

Relevant articles and documents

NEW METHODS FOR β-LACTAM FORMATION FROM β-AMINO ACIDS USING (C6H5)3/CCl4 AND (C6H5)3P/NBS

Triphenylphosphine/carbon tetrachloride and triphenylphosphine/N-bromosuccinimide were found to be very effective for β-lactam formation from β-amino acids in acetonitrile.

A NEW CONVENIENT METHOD FOR β-LACTAM FORMATION FROM β-AMINO ACIDS USING BIS(5'-NITRO-2'-PYRIDYL) 2,2,2-TRICHLOROETHYL PHOSPHATE

Bis(5'-nitro-2'-pyridyl) 2,2,2-trichloroethyl phosphate is found to be a new efficient condensing agent for β-lactam formation from β-amino acids in acetonitrile.

Selective Hydrogenation of 4,5-Dihydro-1,3-oxazin-6-ones to Carbaldehyde Derivatives; Chemical Differentiation between Acylazetidin-2-ones and the Corresponding Isomeric Oxazin-6-ones

Catalytic hydrogenation of optically active and non-active dihydro-oxazin-6-ones unexpectedly led to preferential reduction of the carbonyl group with ring-opening yielding carbaldehyde derivatives.This reaction resolved a structural problem by leading to