145485-79-6

Basic information

• Product Name: tert-butyl 4'-<<3-<(3-tert-butoxycarbonyl)amino>-3-methyl-1-oxobutyl>amino>-<<2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepin-1-yl>methyl><1,1'-biphenyl>-2-carboxylate
• Synonyms: tert-butyl 4'-<<3-<(3-tert-butoxycarbonyl)amino>-3-methyl-1-oxobutyl>amino>-<<2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepin-1-yl>methyl><1,1'-biphenyl>-2-carboxylate
• CAS NO: 145485-79-6
• Molecular Weight: 641.808
• Mol File: 145485-79-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: tert-butyl 4'-<<3-<(3-tert-butoxycarbonyl)amino>-3-methyl-1-oxobutyl>amino>-<<2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepin-1-yl>methyl><1,1'-biphenyl>-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 4'-<<3-<(3-tert-butoxycarbonyl)amino>-3-methyl-1-oxobutyl>amino>-<<2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepin-1-yl>methyl><1,1'-biphenyl>-2-carboxylate(145485-79-6)
• EPA Substance Registry System: tert-butyl 4'-<<3-<(3-tert-butoxycarbonyl)amino>-3-methyl-1-oxobutyl>amino>-<<2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepin-1-yl>methyl><1,1'-biphenyl>-2-carboxylate(145485-79-6)

Safety Data

• Hazardous Substances Data: 145485-79-6(Hazardous Substances Data)

Upstream product

• 114772-36-0 tert-butyl 4'-methyl-2-biphenylcarboxylate 
• 88-65-3 2-bromobenzoic-acid 
• 86499-35-6 3-amino-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one 
• 155300-46-2 N-(tert-butoxycarbonyl)-4,4-dimethylazetidin-2-one 
• 129765-95-3 3-[(tert-butoxycarbonyl)amino]-3-methylbutanoic acid 
• 55666-42-7 tert-butyl 2-bromobenzoate 
• 24424-99-5 di-tert-butyl dicarbonate 
• 4879-95-2 4,4-dimethyl-azetidin-2-one 
• 97278-68-7 3-azido-2,3,4,5-tetrahydro-2-oxo-1 H-1-benzazepine 
• 5720-05-8 4-methylphenylboronic acid 

Relevant articles and documents

A novel 3-substituted benzazepinone growth hormone secretagogue (L- 692,429)

The 3-substituted benzazepinone, L-692,429 (compound 1), is the prototype compound of a novel class of compounds that stimulate release of growth hormone (GH). The molecule evolved from efforts to identify a non-peptide mimic of the growth hormone-releasing hexapeptide, GHRP-6. Compound 1 is prepared by sequential attachment of dimethyl-β-alanine and 2'- biphenylyltetrazole side chains to a chiral 3-aminobenzolactam nucleus. Comparison of the biological activity of 1 with the corresponding six- and eight-membered lactam analogs shows the seven-membered benzazepinone skeleton to be preferred. Molecular modeling of the structurally diverse GH secretagogues, L-692,429 and GHRP-6, was performed.