5297-17-6

Basic information

• Product Name: Succinylmonocholine Chloride (125 mg)
• Synonyms: Succinylmonocholine chloride;Succinylmonocholine Chloride (125 mg);2-(3-Carboxy-1-oxopropoxy)-N,N,N-trimethylethanaminium chloride
• CAS NO: 5297-17-6
• Molecular Formula: C9H18ClNO4
• Molecular Weight: 239.69652
• Mol File: 5297-17-6.mol

Chemical Properties

• Melting Point: 150-151 °C(Solv: ethanol (64-17-5))
• Appearance: /
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: Succinylmonocholine Chloride (125 mg)(CAS DataBase Reference)
• NIST Chemistry Reference: Succinylmonocholine Chloride (125 mg)(5297-17-6)
• EPA Substance Registry System: Succinylmonocholine Chloride (125 mg)(5297-17-6)

Safety Data

• Hazardous Substances Data: 5297-17-6(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
Succinylmonocholine Chloride (125 mg) is used as a neuromuscular blocking agent for facilitating endotracheal intubation and providing muscle relaxation during surgical procedures. It is particularly useful in emergency situations where rapid sequence intubation is required, as well as in elective surgeries that necessitate controlled muscle relaxation.
Used in Research Applications:
In the field of scientific research, Succinylmonocholine Chloride (125 mg) is utilized as a tool to study the neuromuscular blocking action in various animal models, such as rats. This helps researchers understand the mechanisms of muscle paralysis and develop new therapeutic strategies for conditions that involve muscle dysfunction or excessive muscle contractions.
Used in Anesthesia:
Succinylmonocholine Chloride (125 mg) is used as an adjunct to general anesthesia, providing muscle relaxation and facilitating the administration of anesthesia. This allows anesthesiologists to maintain a stable and controlled anesthetic state during surgery, ensuring the patient's comfort and safety.

InChI:InChI=1/C9H17NO4/c1-10(2,3)6-7-14-9(13)5-4-8(11)12/h4-7H2,1-3H3/p+1

Upstream product

• 110-15-6 succinic acid 
• 67-48-1 choline chloride 
• 108-30-5 succinic acid anhydride 

Relevant articles and documents

Degradation properties and pH-responsive guest-release of cyclophanes having four ester side chains with terminal choline residues

Water-soluble cationic cyclophane 1 having four ester side chains with terminal choline residues was synthesized as a pH-responsive degradable host. Alkaline hydrolysis of the ester bonds of 1 gave the corresponding tetraanionic cyclophane 2, which exhibited guest-binding affinities that led to release of the entrapped anionic guest molecules into the bulk aqueous phase.

Analysis and stability of suxamethonium chloride. 1. Detection and quantitative determination of the intact active agent with its degradation products

The authors developed methods permitting to follow the course of degradation in injectable solutions of suxamethonium chloride. The qualitative detection of the active agent in the presence of degradation products is achieved by thin-layer chromatography and spraying with Dragendorff's reagent and bromocresol green indicator solution. The same separation technique may be used for determining with sufficient accuracy the intact agent in the eluate, using the method of Okken and Haas. Furthermore, a modified Draganic procedure (which is based on the spectrophotometric determination of the hydrolysis products succinic acid monocholine chloride and succinic acid as a Cu-benzidine complex) is suited for estimating the degree of degradation. No previous separation is required because the molar extinction efficients of the monoester and of the acid are in agreement, so that the degree of degradation can be calculated from the sum of the molar concentrations. The value of these methods is demonstrated by analyzing experimental mixtures of the intact agent and degradation products.