54885-10-8Relevant articles and documents
Solid sodium hydroxide - THF, convenient system for synthesis esters of glycidic acids by darzens condensation
Gadaj,Kowalkowska,Jonczyk
, p. 577 - 584 (2008/09/19)
Isopropyl- and tert-butylchloroacetate react with carbonyl compounds in the presence of powdered sodium hydroxide in THF, without a catalyst, giving substituted glycidates. The process is applied for preparation of glycidates from ketones, hitherto unavailable by phase-transfer catalyzed Darzens condensation.
Synthesis of enantiomerically pure forms of trans-3-phenylglycidic acid.
Plucinska, Krystyna,Kasprzykowski, Franciszek,Kozian, Elzbieta
, p. 861 - 864 (2007/10/03)
Trans-(2R,3S)- and (2S,3R)-3-phenylglycidic acids were obtained as pure crystals. The optical properties and chemical stability were characterized. The absolute configuration of the trans(+)- and trans-(-) isomers was established by means of chemical correlation.