129939-53-3

Basic information

• Product Name: Methyl (2R,3R)-3-phenyl-1H-aziridine-2-carboxylate
• Synonyms: Methyl (2R,3R)-3-phenyl-1H-aziridine-2-carboxylate
• CAS NO: 129939-53-3
• Molecular Weight: 177.203
• Mol File: 129939-53-3.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Methyl (2R,3R)-3-phenyl-1H-aziridine-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl (2R,3R)-3-phenyl-1H-aziridine-2-carboxylate(129939-53-3)
• EPA Substance Registry System: Methyl (2R,3R)-3-phenyl-1H-aziridine-2-carboxylate(129939-53-3)

Safety Data

• Hazardous Substances Data: 129939-53-3(Hazardous Substances Data)

Upstream product

• 124994-14-5 cis-N-(p-tolylsulfonyl)-2-carbomethoxy-3-phenylaziridine 
• 2272-55-1 ethyl trans-3-phenyl-1-oxirane-2-carboxylate 
• 129939-43-1 Sodium (+)-(2S,3S)-Z-3-phenyl oxirane-2-carboxylate 
• 54885-10-8 sodium (E)-3-phenylglycidate 
• 121-39-1 ethyl cis-3-phenylglycidate 
• 119628-74-9 trans-(4S,5R)-2,2,2,4-Tetraphenyl-5-methoxycarbonyl-1,3,2-oxazaphospholidine 
• 100-52-7 benzaldehyde 
• 19190-80-8 methyl trans-3-phenylglycidate 
• 6362-58-9 methyl phenylpyruvate 
• 500130-99-4 methyl (Z)-3-phenyl-2-trifluoromethylsulfonyloxy propenoate 
• 21770-48-9 methyl 2,3-dibromo-3-phenylpropanoate 
• 140429-60-3 methyl 1-chloro-trans-3-phenylaziridine-2-carboxylate 
• 119628-74-9 cis-(4S^*,5S^*)-2,2,2,4-Tetraphenyl-5-methoxycarbonyl-1,3,2-oxazaphospholidine 
• 25957-39-5 Sodium Z-3-phenyl oxirane-2-carboxylate 

Downstream Products

• 129867-24-9 (2S,3R)-1-(Biphenyl-4-carbonyl)-3-phenyl-aziridine-2-carboxylic acid methyl ester 
• 19185-82-1 Methyl (2R^*,3R^*)-2-(acetylamino)-3-hydroxy-3-phenylpropanoate 
• 141241-05-6 Methyl (2R^*,3S^*)-3-chloro-3-phenyl-2-(tosylamino)propanoate 
• 141241-04-5 Methyl 1-(benzyloxycarbonyl)-trans-3-phenylaziridine-2-carboxylate 
• 19185-82-1 Methyl (2R^*,3S^*)-2-(acetylamino)-3-hydroxy-3-phenylpropanoate 
• 141241-03-4 Methyl 1-acetyl-trans-3-phenylaziridine-2-carboxylate 
• 141241-06-7 Methyl (4R^*,5S^*)-2-methyl-5-phenyloxazoline-4-carboxylate 
• 142619-26-9 trans-3-phenylaziridine-2-carboxylic acid 
• 141240-93-9 (2S,3S)-3-Amino-2-chloro-3-phenyl-propionic acid methyl ester; hydrochloride 
• 140429-64-7 methyl 1-bromo-trans-3-phenylaziridine-2-carboxylate 
• 140429-60-3 methyl 1-chloro-trans-3-phenylaziridine-2-carboxylate 
• 80612-97-1 (Z)-methyl 2-amino-3-phenylacrylate 
• 129866-73-5 (2R,3R)-3-Phenyl-1-(3,3,3-trifluoro-2-methoxy-2-phenyl-propionyl)-aziridine-2-carboxylic acid methyl ester 
• 141241-00-1 Methyl (2R^*,3S^*)-2-amino-3-(indol-3-yl)-3-phenylpropanoat 

Relevant articles and documents

Regiospecific reductive cleavage of the C(2)-N bond of aziridines substituted with an electron acceptor mediated by Mg/MeOH

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Reaction of vinyl triflates of α-keto esters with primary amines: Efficient synthesis of aziridine carboxylates

Vinyl triflates of α-keto esters react smoothly with primary amines to provide aziridine carboxylates in good yields. In all cases, little or no stereoselectivity was observed. A mechanistic study has shown that aziridine carboxylates are strictly formed

A convenient synthesis of aziridine-2-carboxylic esters

Optically active oxirane-2-carboxylic esters, prepared from allylic alcohols employing the Sharpless epoxidation, were treated with sodium azide.The azido alcohols obtained were subsequently converted into aziridine-2-carboxylic esters by reaction with triphenylphosphine, in good yields and with high optical purity.Various racemic oxirane-2-carboxylic esters were subjected to the same sequence of reactions.