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5542-60-9

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5542-60-9 Usage

Description

2-(4-CHLOROPHENOXY)-2-METHYLPROPANOYL CHLORIDE is a chlorinated acyl chloride with the chemical formula C10H11ClO2. It is a key intermediate in the synthesis of pharmaceuticals and agrochemicals, known for its strong acylating properties and versatile reactivity in research and development.

Uses

Used in Pharmaceutical Synthesis:
2-(4-CHLOROPHENOXY)-2-METHYLPROPANOYL CHLORIDE is used as a key intermediate for the production of various pharmaceuticals. Its strong acylating properties allow for the modification of organic molecules, contributing to the development of new drug compounds.
Used in Agrochemical Production:
In the agrochemical industry, 2-(4-CHLOROPHENOXY)-2-METHYLPROPANOYL CHLORIDE is utilized in the production of herbicides and pesticides. Its reactivity enables the creation of effective compounds for controlling weeds and pests in agricultural settings.
Used in Research and Development:
2-(4-CHLOROPHENOXY)-2-METHYLPROPANOYL CHLORIDE is employed in research and development due to its versatile reactivity. It serves as a valuable tool for scientists to explore new chemical reactions and synthesize novel compounds with potential applications in various fields.

Check Digit Verification of cas no

The CAS Registry Mumber 5542-60-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,5,4 and 2 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 5542-60:
(6*5)+(5*5)+(4*4)+(3*2)+(2*6)+(1*0)=89
89 % 10 = 9
So 5542-60-9 is a valid CAS Registry Number.

5542-60-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(4-Chlorophenoxy)-2-methylpropanoyl chloride

1.2 Other means of identification

Product number -
Other names 2-(4-CHLOROPHENOXY)-2-METHYLPROPANOYL CHLORIDE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:5542-60-9 SDS

5542-60-9Relevant articles and documents

The cisplatin-based Pt(iv)-diclorofibrato multi-action anticancer prodrug exhibits excellent performances also under hypoxic conditions

Gabano, Elisabetta,Ravera, Mauro,Trivero, Francesca,Tinello, Stefano,Gallina, Andrea,Zanellato, Ilaria,Gariboldi, Marzia B.,Monti, Elena,Osella, Domenico

, p. 8268 - 8282 (2018)

Multi-action cisplatin-based mono- (1) and di-clofibric acid (2) Pt(iv) "combo" derivatives were synthesized via both traditional and microwave assisted procedures. The two complexes offered very good performances (IC50 values in a nanomolar ra

Discovery of AdipoRon analogues as novel AMPK activators without inhibiting mitochondrial complex I

Chen, Caiping,Cheng, Keguang,Cheng, Yalong,Dai, Liang,Li, Haobin,Qian, Ming,Sun, Geng,Wang, Pengfei,Wen, Xiaoan,Xu, Qing-Long,You, Yanping,Yuan, Haoliang,Zhou, Xinyu

supporting information, (2020/06/08)

Activation of AMPK emerges as a potential therapeutic approach to metabolic diseases. AdipoRon is claimed to be an adiponectin receptor agonist that activates AMPK through adiponectin receptor 1 (AdipoR1). However, AdipoRon also exhibits moderate inhibition of mitochondrial complex I, leading to increased risk of lactic acidosis. In order to find novel AdipoRon analogues that activate AMPK without inhibition of complex I, 27 analogues of AdipoRon were designed, synthesized and biologically evaluated. As results, benzyloxy arylamide B10 was identified as a potent AMPK activator without inhibition of complex I. B10 dose-dependently improved glucose tolerance in normal mice, and significantly lowered fasting blood glucose level and ameliorated insulin resistance in db/db diabetic mice. More importantly, unlike the pan-AMPK activator MK-8722, B10 did not cause cardiac hypertrophy, probably owing to its selective activation of AMPK in the muscle tissue but not in the heart tissue. Together, B10 represents a novel class of AMPK activators with promising therapeutic potential against metabolic disease.

Acetophenone compounds, preparation methods thereof and application thereof in regulating blood lipid

-

Paragraph 0074; 0075; 0076, (2018/09/08)

The invention discloses a compound as shown in formula I or pharmaceutically acceptable salt and a preparation method thereof as well as application thereof in the preparation of drugs for regulatingblood lipid.

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