55832-20-7

Basic information

• Product Name: a-D-Galactopyranoside,3,4-di-O-acetyl-1,6-dichloro-1,6-dideoxy-b-D-fructofuranosyl 4-chloro-4-deoxy-, 2,3,6-triacetate
• Synonyms: a-D-Galactopyranoside,3,4-di-O-acetyl-1,6-dichloro-1,6-dideoxy-b-D-fructofuranosyl 4-chloro-4-deoxy-, triacetate(9CI); 4,1',6'-Trichloro-4,1',6'-trideoxygalactosucrose pentaacetate; Sucralosepentaacetate
• CAS NO: 55832-20-7
• Molecular Formula: C22H29 Cl3 O13
• Molecular Weight: 607.823
• Mol File: 55832-20-7.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: a-D-Galactopyranoside,3,4-di-O-acetyl-1,6-dichloro-1,6-dideoxy-b-D-fructofuranosyl 4-chloro-4-deoxy-, 2,3,6-triacetate(CAS DataBase Reference)
• NIST Chemistry Reference: a-D-Galactopyranoside,3,4-di-O-acetyl-1,6-dichloro-1,6-dideoxy-b-D-fructofuranosyl 4-chloro-4-deoxy-, 2,3,6-triacetate(55832-20-7)
• EPA Substance Registry System: a-D-Galactopyranoside,3,4-di-O-acetyl-1,6-dichloro-1,6-dideoxy-b-D-fructofuranosyl 4-chloro-4-deoxy-, 2,3,6-triacetate(55832-20-7)

Safety Data

• Hazardous Substances Data: 55832-20-7(Hazardous Substances Data)

Upstream product

• 105066-21-5 sucralose-6-acetate 
• 108-24-7 acetic anhydride 
• 56038-13-2 Sucralose 
• 35867-25-5 2,3,6,3',4'-pentaacetyl sucrose (6-PAS) 
• 63648-81-7 6-O-acetyl sucrose 

Downstream Products

• 56038-13-2 Sucralose 

Relevant articles and documents

THERAPEUTIC AGENTS AND METHODS OF PRODUCING SAME

The present invention relates generally to the field of glycanics and its application to the generation of glycoconjugates for therapeutic use. The present invention also relates to process for the preparation of glycoconjugates.

Process for purification of sucralose

The present invention relates to a process for the purification of Sucralose of formula (I) which comprises acetylation of substantially impure Sucralose to its penultimate intermediate 4,1′,6′-trichloro-4,1′,6′-trideoxy galactosucrose penta-acetate (TOPSA) of formula (VI) followed by purification of TOPSA and then deacetylation of purified TOPSA.

PROCESS FOR THE PREPARATION OF SUCROSE-6-ESTER BY ESTERIFICATION IN THE PRESENCE OF SOLID SUPERACID CATALYST

One embodiment of the present invention is a process of making sucrose-6-ester from sucrose by transesterification in the presence of a solid super acid catalyst such as SO42?—TiO2/Al2O3 or SO42?—TiO2. The sucrose-6-acetate is then chlorinated to afford sucralose-6-acetate, using BTC or thionyl chloride. Sucralose-6-acetate is converted into TPSGA for the purpose of purification. TPSGA is de-esterified by sodium methoxide/methanol or sodium ethoxide/ethanol to give sucralose.