57294-38-9

Basic information

• Product Name: BOC-GAMMA-ABU-OH
• Synonyms: NALPHA-tert-Butoxycarbonyl-4-aminobutyric acid;N-t-Butyloxycarbonyl-gamma-aminobutyric acid, Boc-4-Abu-OH;Boc--aminobutyric acid (Boc-GABA);N-Boc-γ-aminobutyric acid, 98+%;Butanoic acid,4-[[(1,1-dimethylethoxy)carbonyl]amino]-;4-(Boc-amino)butyric acid, Boc-GABA;γ-(Boc-amino)butyric acid, 4-(tert-Butoxycarbonylamino)butyric acid, Boc-GABA;4-[(tert-Butyloxycarbonyl)amino]butanoic acid
• CAS NO: 57294-38-9
• Molecular Formula: C₉H₁₇NO₄
• Molecular Weight: 203.24
• EINECS: 1533716-785-6
• Product Categories: Amino Acids;Boc-Amino Acids and Derivative;Unusual Amino Acids
• Mol File: 57294-38-9.mol

Chemical Properties

• Melting Point: 55-59 °C
• Boiling Point: 78-82 °C0.2 mm Hg(lit.)
• Flash Point: >230 °F
• Appearance: White to off-white/Powder
• Density: 1.1886 (rough estimate)
• Vapor Pressure: 4.4E-06mmHg at 25°C
• Refractive Index: 1.4315 (estimate)
• Storage Temp.: 2-8°C
• Solubility: soluble in Methanol
• PKA: 4.70±0.10(Predicted)
• BRN: 1869578
• CAS DataBase Reference: BOC-GAMMA-ABU-OH(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-GAMMA-ABU-OH(57294-38-9)
• EPA Substance Registry System: BOC-GAMMA-ABU-OH(57294-38-9)

Safety Data

• Hazard Codes: Xi
• Statements: 44-36/37/38-22
• Safety Statements: 37/39-26-24/25
• WGK Germany: 3
• F: 10-21
• HazardClass: IRRITANT
• Hazardous Substances Data: 57294-38-9(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
BOC-GAMMA-ABU-OH is used as an intermediate compound for the synthesis of isopropyl-methylcyclohexyl aminobutyrate, a potential anticonvulsant. This application is based on its role in the development of new drugs to treat seizure disorders and other related conditions.
BOC-GAMMA-ABU-OH is used as a chemical building block for the creation of various pharmaceutical compounds, leveraging its unique properties to enhance the effectiveness and safety of medications in the pharmaceutical industry.

InChI:InChI=1/C9H17NO4/c1-9(2,3)14-8(13)10-6-4-5-7(11)12/h4-6H2,1-3H3,(H,10,13)(H,11,12)/p-1

Upstream product

• 1355024-10-0 t-butyl 3-(((perylen-3-yl)methoxy)carbonyl)propylcarbamate 
• 86953-79-9 tert-butyl pyrrolidine-1-carboxylate 

Downstream Products

• 158690-75-6 4-tert-Butoxycarbonylamino-butyric acid tert-butoxycarbonyl-(2-nitro-phenyl)-methyl ester 
• 1026967-39-4 (S)-2-{(S)-2-[(S)-2-(4-tert-Butoxycarbonylamino-butyrylamino)-3-phenyl-propionylamino]-4-methyl-pentanoylamino}-3-phenyl-propionic acid methyl ester 
• 124-38-9 carbon dioxide 
• 220178-26-7 C₆₂H₈₀N₂O₁₇Si 
• 259531-12-9 [3-(2-sulfamoyl-phenylcarbamoyl)-propyl]-carbamic acid tert-butyl ester 
• 276681-97-1 4-(tert-butyloxycarbonylamino)-N-[3-(2,3-dimethylphenylaminosulphonyl)phenyl]butyric acid amide 
• 710282-49-8 2-[2-(4-tert-butoxycarbonylamino-butyrylamino)-3-(1H-indol-3-yl)-propionylamino]-3-phenyl-propionic acid tert-butyl ester 
• 195144-89-9 Boc-4-aminobutyryl p-nitrophenyl ester 
• 618068-92-1 N-Boc-4-aminobutyric acid 1-methyl-2-[2-(2-methyl-[1,3]dioxolan-2-yl)-phenyl]-ethyl ester 
• 620598-25-6 7-phenoxy-3,4-dihydro-1-[4-(tert-butoxycarbonylamino)butyryl]-2H-quinoline-4-spiro-5'-1'-methyl-3'-(1-tert-butoxycarbonyl-1H-indol-3-ylmethyl)-imidazolidine-2',4'-dione 
• 753483-19-1 [3-(3-{[1-(4-methoxy-phenyl)-methylidene]amino}pyridin-4-ylcarbamoyl)propyl]carbamic acid tert-butyl ester 
• 266000-49-1 1,4,7,10,13-pentakis(γ-aminobutylcarbonyl)-1,4,7,10,13-pentaaza-cyclopentadecane 
• 431881-59-3 N-[2-[3-benzoyl-4-[(4-methylphenyl)acetylamino]phenyl]]-N^γ-tert-butyloxycarbonyl-γ-aminobutyric acid amide 

Relevant articles and documents

PHOTOLYTIC COMPOUNDS AND TRIPLET-TRIPLET ANNIHILATION MEDIATED PHOTOLYSIS

The invention provides novel photolytic compounds and prodrugs, nanoparticles and compositions thereof, and methods of conducting photolysis mediated by triplet-triplet annihilation.

Ruthenium tetroxide oxidation of cyclic N-acylamines by a single layer method: formation of ω-amino acids

The ruthenium tetroxide oxidation of cyclic N-acyl amines by a 10% NaIO4 aqueous solution containing tert-butanol as a single layer system resulted in the endo-cyclic C-N bond cleavage to afford the ω-amino acids as almost sole products in good yields, while a similar oxidation under the double layer using a NaIO4 aqueous solution, and ethyl acetate gave the N-acyl lactams.