61040-81-1

Basic information

• Product Name: 3,5-DIMETHOXY-4-METHYLBENZOIC ACID
• Synonyms: LABOTEST-BB LT00455447;3,5-DIMETHOXY-P-TOLUIC ACID;3,5-DIMETHOXY-4-METHYLBENZOIC ACID;5-DiMethoxy-4-Methylbenzoic acid
• CAS NO: 61040-81-1
• Molecular Formula: C₁₀H₁₂O₄
• Molecular Weight: 196.2
• Product Categories: Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Acids & Esters;Anisoles, Alkyloxy Compounds & Phenylacetates
• Mol File: 61040-81-1.mol

Chemical Properties

• Melting Point: 210-216°C
• Boiling Point: 347.7 °C at 760 mmHg
• Flash Point: 137.8 °C
• Appearance: /
• Density: 1.18g/cm³
• Vapor Pressure: 1.99E-05mmHg at 25°C
• Refractive Index: 1.53
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: Soluble in liquid ammonia.
• PKA: 4.13±0.10(Predicted)
• BRN: 2695238
• CAS DataBase Reference: 3,5-DIMETHOXY-4-METHYLBENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-DIMETHOXY-4-METHYLBENZOIC ACID(61040-81-1)
• EPA Substance Registry System: 3,5-DIMETHOXY-4-METHYLBENZOIC ACID(61040-81-1)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-37
• Hazardous Substances Data: 61040-81-1(Hazardous Substances Data)

Usage

Uses

Used in Chemical Synthesis:
3,5-Dimethoxy-4-methylbenzoic acid is used as a starting material for the synthesis of various organic compounds. It can undergo reduction in the presence of sodium in ethanol to prepare 1,4-dihydro-3,5-dimethoxy-4-methylbenzoic acid, which can be further used in the production of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 3,5-dimethoxy-4-methylbenzoic acid is used as an intermediate for the synthesis of various drugs and drug candidates. Its unique chemical structure allows for the development of new compounds with potential therapeutic applications.
Used in Agrochemical Industry:
3,5-Dimethoxy-4-methylbenzoic acid is also used in the agrochemical industry for the synthesis of pesticides and other crop protection agents. Its chemical properties make it a valuable building block for the development of new and effective agrochemical products.
Used in Specialty Chemicals:
In the specialty chemicals sector, 3,5-dimethoxy-4-methylbenzoic acid is used as a key component in the production of various specialty chemicals, such as dyes, pigments, and fragrances. Its versatility in chemical reactions enables the creation of a wide range of products with unique properties and applications.

InChI:InChI=1/C10H12O4/c1-6-8(13-2)4-7(10(11)12)5-9(6)14-3/h4-5H,1-3H3,(H,11,12)

Upstream product

• 21390-25-0 1,3-dimethoxy-2,5-dimethylbenzene 
• 874514-68-8 (4-carboxy-2,6-dimethoxy-phenyl)-acetic acid 
• 108-24-7 acetic anhydride 
• 28026-96-2 3,5-dihydroxy-4-methylbenzoic acid 
• 77-78-1 dimethyl sulfate 
• 1132-21-4 3,5-dimethoxybenzoic acid 
• 74-88-4 methyl iodide 
• 91-22-5 quinoline 
• 99-75-2 4-methyl-benzoic acid methyl ester 
• 74896-66-5 Methyl 3,5-Dibromo-4-methylbenzoate 
• 60441-79-4 methyl 3,5-dimethoxy-4-methylbenzoate 

Downstream Products

• 60441-79-4 methyl 3,5-dimethoxy-4-methylbenzoate 
• 34523-76-7 3,5-dimethoxy-4-methylbenzoyl chloride 
• 159429-49-9 N,N-diisopropyl-3,5-dimethoxy-4-methylbenzamide 
• 676541-51-8 2-formyl-N,N-diisopropyl-3,5-dimethoxy-4-methylbenzamide 
• 676541-52-9 2-[(2-hydroxy-ethylamino)-methyl]-N,N-diisopropyl-3,5-dimethoxy-4-methyl-benzamide 
• 91012-99-6 3,5-dimethoxy-4-methyl-benzoic acid amide 
• 724771-83-9 3-(3,5-dimethoxy-4-methyl-phenyl)-3-oxo-propionic acid ethyl ester 
• 875817-66-6 2-(3,5-dimethoxy-4-methyl-benzoyl)-3-oxo-butyric acid ethyl ester 
• 21466-46-6 ω-Diazo-3,5-dimethoxy-4-methyl-acetophenon 

Relevant articles and documents

Preparation method of 3,5-dimethoxy-4-methyl benzoic acid

The invention discloses a preparation method of 3,5-dimethoxy-4-methyl benzoic acid, which comprises the following steps: adding methyl 4-methyl benzoate in a first organic solvent, adding bromine, and carrying out bromination reaction to obtain methyl 3,

Selective para metalation of unprotected 3-methoxy and 3,5-dimethoxy benzoic acids with n-butyl lithium-potassium tert-butoxide (LIC-KOR): Synthesis of 3,5-dimethoxy-4-methyl benzoic acid

The potassium salt of 3-methoxy and 3,5-dimethoxy benzoic acids undergoes deprotonation at the position para to the carboxylate group selectively when treated with LIC-KOR in THF at -78°C and it has been extended to the synthesis of 3,5-dimethoxy-4-methyl benzoic acid. (C) 2000 Elsevier Science Ltd.

Process for aromatic ethers

A process for the preparation of aromatic ethers by the bromination of a compound of the formula STR1 wherein R1, independently, is hydrogen, hydroxy, lower alkoxy, lower alkyl; m is an integer from 1-4, and A is --CHO, --COOR3 or lower alkyl, and subsequently treating the reaction product of the bromination step with an alkali metal alkoxide in the presence of cuprous halide or oxide, is described.