Welcome to LookChem.com Sign In|Join Free

CAS

  • or

6118-51-0

Post Buying Request

6118-51-0 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier
  • Exo-3, 6-Epoxy-1, 2, 3, 6-Tetrahydrophthalic Anhydride

    Cas No: 6118-51-0

  • No Data

  • 1 Metric Ton

  • 1 million Metric Ton/Year

  • COLORCOM LTD.
  • Contact Supplier

6118-51-0 Usage

Uses

Intermediate in a useful synthesis of 4,4-dialkyl-2-butenolides, based on reaction with two moles of Grignard reagent, followed by cycloreversion (elimination of furan) to release the double bond.

Check Digit Verification of cas no

The CAS Registry Mumber 6118-51-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,1,1 and 8 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 6118-51:
(6*6)+(5*1)+(4*1)+(3*8)+(2*5)+(1*1)=80
80 % 10 = 0
So 6118-51-0 is a valid CAS Registry Number.
InChI:InChI=1/C8H6O4/c9-7-5-3-1-2-4(11-3)6(5)8(10)12-7/h1-6H/t3-,4+,5-,6+

6118-51-0 Well-known Company Product Price

  • Brand
  • (Code)Product description
  • CAS number
  • Packaging
  • Price
  • Detail
  • Alfa Aesar

  • (L03620)  exo-7-Oxabicyclo[2.2.1]hept-5-ene-2,3-dicarboxylic anhydride, 98+%   

  • 6118-51-0

  • 5g

  • 158.0CNY

  • Detail
  • Alfa Aesar

  • (L03620)  exo-7-Oxabicyclo[2.2.1]hept-5-ene-2,3-dicarboxylic anhydride, 98+%   

  • 6118-51-0

  • 25g

  • 290.0CNY

  • Detail
  • Alfa Aesar

  • (L03620)  exo-7-Oxabicyclo[2.2.1]hept-5-ene-2,3-dicarboxylic anhydride, 98+%   

  • 6118-51-0

  • 100g

  • 870.0CNY

  • Detail
  • Aldrich

  • (330736)  exo-3,6-Epoxy-1,2,3,6-tetrahydrophthalicanhydride  

  • 6118-51-0

  • 330736-25G

  • 709.02CNY

  • Detail
  • Aldrich

  • (330736)  exo-3,6-Epoxy-1,2,3,6-tetrahydrophthalicanhydride  

  • 6118-51-0

  • 330736-100G

  • 1,946.88CNY

  • Detail

6118-51-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name exo-3,6-Epoxy-1,2,3,6-tetrahydrophthalic anhydride

1.2 Other means of identification

Product number -
Other names anhydride of rel-(1R,2S,3R,4S)-7-oxabicyclo[2.2.1]hept-5-ene-2,3-dicarboxylic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:6118-51-0 SDS

6118-51-0Synthetic route

furan
110-00-9

furan

maleic anhydride
108-31-6

maleic anhydride

exo-3,6-epoxy-1,2,3,6-tetrahydrophthalic anhydride
6118-51-0

exo-3,6-epoxy-1,2,3,6-tetrahydrophthalic anhydride

Conditions
ConditionsYield
In neat (no solvent, solid phase) for 1h; Diels-Alder Cycloaddition; Milling;100%
In toluene at 110℃; for 24h; Diels-Alder Cycloaddition; Reflux; stereospecific reaction;100%
at 25℃; for 16h; Diels-Alder reaction;98%
furan
110-00-9

furan

maleic anhydride
108-31-6

maleic anhydride

A

exo-3,6-epoxy-1,2,3,6-tetrahydrophthalic anhydride
6118-51-0

exo-3,6-epoxy-1,2,3,6-tetrahydrophthalic anhydride

B

endo, cis-7-oxabicyclo<2.2.1>hept-5-ene-2,3-dicarboxylic acid
51112-81-3

endo, cis-7-oxabicyclo<2.2.1>hept-5-ene-2,3-dicarboxylic acid

Conditions
ConditionsYield
With trans-1,2-bis(4-pyridyl)ethylene In neat (no solvent, solid phase) for 25h; Milling;A 93%
B 7%
With trans-1,2-bis(4-pyridyl)ethylene In neat (no solvent, solid phase) for 25h; Milling; UV-irradiation;A 35%
B 65%
furan
110-00-9

furan

maleic anhydride
108-31-6

maleic anhydride

diethyl ether
60-29-7

diethyl ether

exo-3,6-epoxy-1,2,3,6-tetrahydrophthalic anhydride
6118-51-0

exo-3,6-epoxy-1,2,3,6-tetrahydrophthalic anhydride

Conditions
ConditionsYield
In diethyl ether at 38℃; for 1h;85.75%
furan
110-00-9

furan

maleic anhydride
108-31-6

maleic anhydride

A

exo-3,6-epoxy-1,2,3,6-tetrahydrophthalic anhydride
6118-51-0

exo-3,6-epoxy-1,2,3,6-tetrahydrophthalic anhydride

B

7-oxabicyclo<2.2.1>heptene-exo-2,3-dicarboxylic anhydride
6766-44-5

7-oxabicyclo<2.2.1>heptene-exo-2,3-dicarboxylic anhydride

Conditions
ConditionsYield
In acetone at 20℃; under 760 Torr; for 282h; Kinetics; Product distribution; effect of high pressure: different pressures and times; rate constants; 40 deg C, deuteroacetonitrile;
In acetone at 20℃; under 735059 Torr; Thermodynamic data; Kinetics; Rate constant; other pressure, ΔV(excit);
With K10 montmorillonite at 0℃; for 3h; Yield given; Yields of byproduct given. Title compound not separated from byproducts;
In ethyl acetate at 20℃; Kinetics; Diels-Alder reaction;
In ethyl acetate at 20℃; Diels-Alder reaction;
furan
110-00-9

furan

maleic anhydride
108-31-6

maleic anhydride

diethyl ether
60-29-7

diethyl ether

A

exo-3,6-epoxy-1,2,3,6-tetrahydrophthalic anhydride
6118-51-0

exo-3,6-epoxy-1,2,3,6-tetrahydrophthalic anhydride

B

7-oxa-norborn-5-ene-2endo,3endo-dicarboxylic acid-anhydride

7-oxa-norborn-5-ene-2endo,3endo-dicarboxylic acid-anhydride

furan
110-00-9

furan

maleic anhydride
108-31-6

maleic anhydride

water
7732-18-5

water

A

exo-3,6-epoxy-1,2,3,6-tetrahydrophthalic anhydride
6118-51-0

exo-3,6-epoxy-1,2,3,6-tetrahydrophthalic anhydride

B

7-oxa-norborn-5-ene-2endo,3endo-dicarboxylic acid-anhydride

7-oxa-norborn-5-ene-2endo,3endo-dicarboxylic acid-anhydride

Conditions
ConditionsYield
Product distribution; Einfluss der Reaktionsdauer auf die Ausbeute;
furan
110-00-9

furan

maleic anhydride
108-31-6

maleic anhydride

A

exo-3,6-epoxy-1,2,3,6-tetrahydrophthalic anhydride
6118-51-0

exo-3,6-epoxy-1,2,3,6-tetrahydrophthalic anhydride

B

maleic acid
110-16-7

maleic acid

Conditions
ConditionsYield
With water for 1h; Diels-Alder Cycloaddition; Inert atmosphere; Darkness;A 68 %Spectr.
B n/a
furan
110-00-9

furan

succinic acid anhydride
108-30-5

succinic acid anhydride

exo-3,6-epoxy-1,2,3,6-tetrahydrophthalic anhydride
6118-51-0

exo-3,6-epoxy-1,2,3,6-tetrahydrophthalic anhydride

Conditions
ConditionsYield
In ethyl acetate at 20℃;

6118-51-0Relevant articles and documents

EFFECT OF HIGH PRESSURE ON THE RATE CONSTANT OF THE DIELS-ALDER REACTION BETWEEN FURAN AND MALEIC ANHYDRIDE

Zhulin, V. M.,Kel'tseva, M. V.,Bogdanov, V. S.,Koreshkov, Yu. D.,Kabotyanskaya, E. B.

, p. 456 - 459 (1990)

The effect of high pressure (up to 700 MPa) on the rate of the Diels-alder reaction between furan and maleic anhydride has been investigated in deuterated acetone at 20 deg C.The volume effect of the reaction at atmospheric pressure is found to be ΔV

Antimicrobial activities of phosphonium containing polynorbornenes

Süer, N. Ceren,Demir, Ceren,ünübol, Nihan A.,Yal?in, ?zlem,Kocag?z, Tanil,Eren, Tarik

, p. 86151 - 86157 (2016)

In this study, amphiphilic polyoxanorbornene with different alkyl and aromatic phosphonium side chains was synthesized. The biological activities of these polymers were determined by the minimal inhibitory concentration (MIC) against E. coli, S. aureus, M. tuberculosis and the yeast C. albicans, and cytotoxicity studies on red blood cells were performed. A series of polymers with different alkyl and aromatic substituents (methyl, ethyl, tripropyl, tert-butyl, phenyl, and tris 4-methoxyphenyl) and two types different molecular weight, 3000 g mol-1 and 10 000 g mol-1, were prepared. It was observed that the biological activity of the polymers with aromatic group substituents had an MIC of 16, 8, 64 and 128 μg mL-1 against E. coli, S. aureus, M. tuberculosis and C. albicans, respectively, while those with non-aromatic carbons had a higher MIC compared to those with aromatic carbons. The aromaticity of the repeat unit had impressive effects on hemolytic activities as well. Zeta potential measurements of E. coli incubated with active and inactive polymer concentration revealed a relationship between the MIC and membrane surface charge density. Polymers bearing aromatic groups killed the bacteria with widespread damage after the polymers, holding the threshold concentration, were added to the bacteria.

Hierarchical preferences of hydroxylated oxanorbornane-based achiral amphiphiles

Janni, D. Sirisha,Manheri, Muraleedharan K.

, p. 15182 - 15190 (2013)

Achiral amphiphiles with hydroxylated oxanorbornane headgroups showed specific morphological characteristics and hierarchical preferences depending upon the nature of lipophilic units. Detailed scanning electron microscopic (SEM) studies showed that twist

Cyclohexanedicarboxylic acid derivative with bridge ring and pharmaceutical composition and application thereof

-

Paragraph 0081-0085, (2021/11/10)

The invention discloses a cyclohexane dicarboxylic acid derivative with a bridged ring represented by general formula (I). The application of the stereoisomers and the pharmaceutically acceptable salts in the preparation of antitumor drugs has obvious inhibition effects on leukemia, liver cancer, lung cancer, gastric cancer and ovarian cancer. The compound disclosed by the invention has high anti-tumor activity, wide anti-tumor spectrum and low toxicity, and is suitable for preparing anti-cancer drugs.

Synthesis of l-ascorbic acid-amino acid-norcantharidin conjugates and their biological activity evaluation in vitro

Wang, Xianheng,Wu, Caoyuan,Zhang, Jidong,Zhao, Changkuo,Zhou, Yiqi

, (2022/01/06)

Three components of L-ascorbic acid, amino acid and functionalized norcantharidins were constructed together in several steps to form 42 norcantharidin derivatives in a high yield. The structure of these synthesized l-ascorbic acid-amino acid-norcantharidin conjugates are determined by 1HNMR, 13CNMR and MS spectrum. The results showed that compounds 6e, 6g, 6j, 6l, 6m, 6b, 6e, 6i, and 6n showed high cytotoxicity to HepG2 and compounds 6b, 6e-g, 6l, 6n, 7b, 7d, 7h, 7i, 7n, 8g, 8i exhibited high cytotoxicity to SW480; Meanwhile, besides 6b, 6e, 6g, and 6k, the other compounds showed less toxic to LO2 at a concentration of 50 μg/mg after 72 h. Compound 6g can induce Mφ-type macrophages derived from mouse bone marrow to polarize to M1-type macrophages.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 6118-51-0