6125-63-9 Usage
Description
(E)-3-(2-furyl)acrylonitrile, with the molecular formula C7H5NO, is a yellow liquid chemical compound characterized by a strong, sweet, and nutty odor. It is known for its versatile applications in various industries, including the production of perfumes, pharmaceuticals, and other organic chemicals. Additionally, it serves as a precursor in organic synthesis reactions, particularly in the formation of heterocyclic compounds. However, it is considered a hazardous chemical, necessitating careful handling and storage to prevent irritation to the skin, eyes, and respiratory system.
Uses
Used in Perfume Industry:
(E)-3-(2-furyl)acrylonitrile is used as a fragrance ingredient for its strong, sweet, and nutty odor, contributing to the creation of various perfumes and scented products.
Used in Pharmaceutical Industry:
(E)-3-(2-furyl)acrylonitrile is used as a building block in the synthesis of pharmaceutical compounds, playing a crucial role in the development of new drugs and medications.
Used in Organic Chemicals Production:
(E)-3-(2-furyl)acrylonitrile is used as a raw material in the production of various organic chemicals, contributing to the synthesis of a wide range of chemical products.
Used in Organic Synthesis Reactions:
(E)-3-(2-furyl)acrylonitrile is used as a precursor in organic synthesis reactions, particularly in the formation of heterocyclic compounds, which are important in the development of new chemical entities and materials.
Safety Precautions:
Due to its hazardous nature, (E)-3-(2-furyl)acrylonitrile requires careful handling and storage to minimize exposure and potential health risks. It is essential to follow safety regulations and guidelines to ensure the well-being of individuals working with this compound.
Check Digit Verification of cas no
The CAS Registry Mumber 6125-63-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,1,2 and 5 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 6125-63:
(6*6)+(5*1)+(4*2)+(3*5)+(2*6)+(1*3)=79
79 % 10 = 9
So 6125-63-9 is a valid CAS Registry Number.
6125-63-9Relevant articles and documents
Preparation method of nitrile compound
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Paragraph 0072-0074, (2022/01/08)
The present invention belongs to the field of organic synthesis technology, specifically relates to a method for preparing a nitrile compound, aldehyde oxime derivatives as raw materials, adding DPPA and DBU, reacting in an organic solvent, one step to pr
One-Pot Synthesis of α,β-Unsaturated Esters, Ketones, and Nitriles from Alcohols and Phosphonium Salts
Ding, Weijie,Hu, Juan,Jin, Huile,Yu, Xiaochun,Wang, Shun
, p. 107 - 118 (2017/09/28)
A general method for the synthesis of α,β-unsaturated esters, ketones, and nitriles is successfully achieved by a one-pot copper-catalyzed oxidation with O 2 in air as oxidant. The solvent mixture of acetonitrile and formamide (1:1) is optimized to ensure the oxidation of alcohols, deprotonation of phosphonium salt, and Wittig reaction occur efficiently in one pot. A broad range of substrates has been explored for this process, including three electron-withdrawing group (CO 2 Et, COPh, CN) functionalized phosphonium salts. They reacted not only with benzylic and heteroaromatic alcohols, but also with aliphatic alcohols, forming the corresponding α,β-unsaturated esters, ketones, and nitriles in moderate to excellent yields.
Selective and facile synthesis of α,β-unsaturated nitriles and amides with N-hydroxyphthalimide as the nitrogen source
Yan, Yiyan,Xu, Xiaohe,Jie, Xiaokang,Cheng, Jingya,Bai, Renren,Shuai, Qi,Xie, Yuanyuan
supporting information, p. 2793 - 2796 (2018/06/25)
The direct conversion of α,β-unsaturated aldehydes to corresponding nitriles promoted by Pd(OAc)2 and phthalic acid which was hydrolyzed from N-hydroxyphthalimide (NHPI) has been disclosed. Additionally, it was found that when water was used as the solvent, α,β-unsaturated amides was obtained as the main products in good to excellent yields. It was first reported that NHPI was utilized as the nitrogen source to synthesize α,β-unsaturated nitriles and amides from aldehydes. Control experiment demonstrated that aldehydes undergo a process of oximation and dehydration to form nitriles and amides.