6196-94-7Relevant articles and documents
Continuous synthesis of organozinc halides coupled to Negishi reactions
Alonso, Nerea,Miller, L. Zane,De M. Muoz, Juan,Alczar, Jesus,McQuade, D. Tyler
supporting information, p. 3737 - 3741 (2015/01/16)
The Negishi cross-coupling is a powerful C-C bond forming reaction. The method is less commonly used relative to other cross-coupling methods in part due to lack of availability of organozinc species. While organozinc species can be prepared, problems wit
Selective one-pot synthesis of various phenols from diarylethanes
Nakamura, Ryota,Obora, Yasushi,Ishii, Yasutaka
supporting information; experimental part, p. 3417 - 3419 (2009/02/05)
Various substituted phenols were selectively synthesized by a one-pot reaction through the NHPI-catalyzed aerobic oxidation of 1,1-diarylethanes followed by treatment with dilute sulfuric acid. The Royal Society of Chemistry.
Selective arylation of exocyclic N-position of 2-pyrimidylnitrenium ion photolytically generated from tetrazolo[1,5-a]pyrimidine in the presence of trifluoroacetic acid
Takeuchi, Hiroshi,Watanabe, Keiichi
, p. 478 - 484 (2007/10/03)
Photo-reactions of tetrazolo[1,5-a]pyrimidine (1) with benzene (2a) and substituted benzenes (2b-f) in the presence of trifluoroacetic acid (TFA) gave 2-(2-, 3- and 4-substituted anilino)pyrimidines (3-5) together with 2-aminopyridine (6) and biphenyl (7) or diarylmethanes (8b, 8c and 8e). From the effect of heavy-atom solvent on the reactions, it is reasonable to assume that 3-5 are formed via a singlet species, but 6-8 via a triplet species. The intermediacy of 2-pyrimidylnitrenium ion is consistent with the evidence derived by the above effect, by a Hammett plot with p = -2.9 and by effects of solvent nucleophilicity and counter-anions. The selective exocyclic N-arylation giving 3-5 is discussed.