62761-89-1Relevant articles and documents
Regioselective C-H activation and sequential C-C and C-O bond formation reactions of aryl ketones promoted by an yttrium carbene
Mills, David P.,Soutar, Lyndsay,Lewis, William,Blake, Alexander J.,Liddle, Stephen T.
supporting information; experimental part, p. 14379 - 14381 (2010/12/25)
Rare earth carbenes exclusively exhibit Wittig-type reactivity with carbonyl compounds to afford alkenes. Here, we report that yttrium carbenes can effect regioselective ortho-C-H activation and sequential C-C and C-O bond formation reactions of aryl ketones to give iso-benzofurans and hydroxymethylbenzophenones. With MeCOPh, cyclotetramerization occurs giving a substituted cyclohexene. This demonstrates new rare earth carbene reactivity which complements existing Wittig-type reactivity.