65236-40-0Relevant articles and documents
Visible-Light-Mediated Late-Stage Sulfonylation of Anilines with Sulfonamides
Chu, Man-Hei,Du, Xian,Li, Yi-Hui,Luo, Yong,Xu, Xiao-Hong,Yuan, Han,Zhen, Jing-Song
, p. 853 - 858 (2022/02/05)
A visible-light-mediated late-stage sulfonylation of anilines with sulfonamides under simple reaction conditions is presented. Various primary or secondary sulfonamides including several pharmaceuticals were incorporated successfully via N–S bond activati
An efficient method for the synthesis of N-acylsulfonamides: One-pot sulfonylation and acylation of primary arylamines under solvent-free conditions
Massah, Ahmad R.,Azadi, Davood,Aliyan, Hamid,Momeni, Ahmad R.,Naghash, Hamid Javaherian,Kazemi, Foad
experimental part, p. 233 - 240 (2009/05/26)
The preparation of N-acylsulfonamides is described using primary amines, arylsulfonyl chlorides and acyl chlorides. Reaction of primary aryl amines with arylsulfonyl chlorides in the presence of NaHCO3 produced N-arylsulfonamides, which reacted in situ with benzoyl chloride furnishing the corresponding N-benzoyl-N-arylsulfonamides in 72-96% yields. Accordingly, 4-nitrobenzoyl chloride and 3,5-dinitrobenzoyl chloride were used as acylating agents. All the reactions were carried out under solvent-free conditions at room temperature and the products were isolated after simple work-up in high yields and purity.
